Methodological aspects of ensuring and improving diagnostic effectiveness of quantitative immunochemiluminescent studies. Model of ‘clinical uncertainty’ as part of laboratory modules of clinical recommendations and educational programs
https://doi.org/10.33667/2078-5631-2022-6-30-34
Abstract
Technological capabilities make it possible to increase the diagnostic efficiency of quantitative immunochemiluminescent studies but require expanding the glossary of the clinical and laboratory consultation, taking into account metrological approaches to quality assurance. The variants of quantitative assessment of the “clinical uncertainty of assessing the patient’s condition based on a laboratory test”, formed taking into account the models of analytical quality requirements, are proposed. The clinical significance of the introduction of metrological approaches to ensuring and expressing accuracy in the practice of quantitative immunochemiluminescent studies in order to reduce risks and improve the safety of medical activities is demonstrated.
About the Authors
N. A. Kovyazina
All-Russian Centre for Emergency and Radiation Medicine n.a. A.M. Nikiforov
Russian Federation
Russian Federation
Kovyazina Nadezhda A., PhD Med, head of the Laboratory for Serological Research and Allergy Diagnostics, Dept of Laboratory Diagnostics
Saint Petersburg
S. S. Aleksanin
All-Russian Centre for Emergency and Radiation Medicine n.a. A.M. Nikiforov
Russian Federation
Russian Federation
Aleksanin Sergey Sergeevich, DM Sci (habil.), pofessor, Corresponding Member of RAS, director
Saint Petersburg
A. G. Chunovkina
All-Russian Scientific Research Institute for Metrology n.a. D. I. Mendeleev;Interregional Public Association ‘Metrological Academy
Russian Federation
Russian Federation
Chunovkina A.G., DTech. Sic, head of the Research Laboratory
Saint Petersburg
V. L. Emanuel
Interregional Public Association ‘Metrological Academy; First Saint Petersburg State Medical University n.a. academician I.P. Pavlov
Russian Federation
Russian Federation
Emanuel Vladimir L.2,4, DM Sci (habil.), professor, head of Dept of Clinical Laboratory Diagnostics with a Course in Molecular Medicine, director of Scientific and Methodological Center for Molecular Medicine, academician of Metrological Academy
Saint Petersburg
References
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Review
For citations:
Kovyazina N.A., Aleksanin S.S., Chunovkina A.G., Emanuel V.L. Methodological aspects of ensuring and improving diagnostic effectiveness of quantitative immunochemiluminescent studies. Model of ‘clinical uncertainty’ as part of laboratory modules of clinical recommendations and educational programs. Medical alphabet. 2022;1(6):30-34. (In Russ.) https://doi.org/10.33667/2078-5631-2022-6-30-34
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