Importance of herpes simplex virus in development of infertility in married couples
https://doi.org/10.33667/2078-5631-2021-32-16-19
Abstract
The article considers the role of herpes simplex viruses of 1st, 2nd types in the development of reproductive disorders in married couples. The clinical example shows the difficulties of diagnosis, possible errors in treatment approaches, and the lack of results from the use of artificial insemination methods in the presence of persistent herpetic infection. Prolonged antiviral therapy led to the onset of pregnancy and the birth of a child.
About the Authors
E. K. ShushakovaRussian Federation
Shushakova Ekaterina K., junior researcher at Clinical Dept of Infectious Pathology
Moscow
N. A. Meshkova
Russian Federation
Meshkova Natalia A., student of 3th year of Faculty ‘Clinical Institute of Children's Health n. a. N. F. Filatov
Moscow
D. A. Khavkina
Russian Federation
Khavkina Daria А., junior researcher at Clinical Dept, physician of Clinical and Diagnostic Centre
Moscow
P. V. Chukhliaev
Russian Federation
Chukhliaev Pavel V., junior researcher at Scientific Clinical and Diagnostic Dept, physician of Clinical and Diagnostic Centre
Moscow
T. A. Ruzhentsova
Russian Federation
Ruzhentsova Tatiana A., DM Sci (habil.), professor, deputy director for clinical work, head of Dept of Internal Medicine
Moscow
References
1. Pascar S. S. Epidemiological aspects of infertile marriage (literature review). S. S. Pascar, K. Yu. Boyarsky. Reproduction Problems. 2017. No. 23 (5). S. 23–26.
2. Mardanly S. G., Simonova E. G., Simonov V. V. Herpesvirus infections: etiology and pathogenesis, clinical picture and laboratory diagnostics, epidemiology and prevention. Orekhovo-Zuevo: State Technical University, 2020; 316 s.
3. Medvedev B. I., Teplova S. N., Zainetdinova L. F. Diagnosis of genital herpesvirus infection in women with tuboperitoneal infertility. Journal of Microbiology, Epidemiology and Immunology. 2009; 2: 80–5.
4. Kushch A. A., Kisteneva L. B., Klimova R. R., Cheshik S. G. The role of herpes viruses in the development of diseases of the urogenital tract and infertility in women. Virology Issues. 2020; 65 (6): 317–325.
5. Tata S., Johnston C., Huang M. L. et al. Overlapping reactivations of herpes simplex virus type 2 in the genital and perianal mucosa. J Infect Dis. 2010; 201 (4): 499–504.
6. Abdulmedzhidova A. G., Rog K. V., Zavalishina L. E., Kushch A. A. Intrafollicular herpes simplex virus infection of mammalian and human oocytes. Virology Issues. 2014; T. 59 (1). S. 42–46.
7. Shushakova E. K., Ruzhentsova T. A., Nikolaeva S. V. The mechanisms of influence of herpes simplex viruses in non-developing pregnancies. Infectious Diseases. 2019.Vol. 17. No. 3. P. 15–19.
8. Naumenko V. A. Detection of herpes simplex virus and cytomegalovirus in male germ cells during experimental infection in vitro and in the ejaculate of men with impaired fertility: abstract of thesis. … candidate of medical sciences: 03.00.06. Naumenko Viktor Alekseevich [Place of defense: Research Institute of Virology n. a. D. I. Ivanovsky of RAMS]. Virology. Moscow, 2009. 26 p.
9. Bocharova E. N., Kurilo L. F., Shileiko L. V., Bragina E. E., Yurov Yu.B., Vorsanova S. G. and other Analysis of the population of germ cells in the ejaculate of men infected with the herpes simplex virus. Ontogenesis. 2008; 39 (1): 47–57.
10. Tyulenev Yu. A. The effect of herpes simplex virus and cytomegalovirus on male germ cells and spermatogenesis in experimental infection in vitro and in vivo: abstract of thesis. … candidate of biological sciences: 03.01.03. Tyulenev Yuri Alexandrovich [Place of defense: Scientific research. Research Institute of Virology n. a. D. I. Ivanovsky of RAMS]. Moscow, 2012. 25 p.
11. Sergeev O. V., Boshyan R. E., Barinsky I. F., Highly productive sequencing in the diagnosis and prevention of herpes simplex infection. Virology Issues. 2020; 65 (3): 126–131.
12. Ahmed R, Kiani IG, Shah F, et al. Herpes simplex encephalitis presenting with normal csf analysis. J Coll Physicians Surg Pak. Nov; 23 (10): 815–7. DOI: 11.2013/JCPSP.
Review
For citations:
Shushakova E.K., Meshkova N.A., Khavkina D.A., Chukhliaev P.V., Ruzhentsova T.A. Importance of herpes simplex virus in development of infertility in married couples. Medical alphabet. 2021;(32):16-19. (In Russ.) https://doi.org/10.33667/2078-5631-2021-32-16-19