Role of magnetic resonance imaging in prediction of chondrosarcoma of bone grade
https://doi.org/10.33667/2078-5631-2020-38-21-24
Abstract
Purpose. Determining the diagnostic value of magnetic resonance imaging in the accurate definition of chondrosarcoma of bone grade at the pre-surgery examination. Material and methods. We analyzed examination data (magnetic resonance imaging with no contrast enhancement) of 70 patients with chondrosarcoma (35 patients with low-grade chondrosarcoma and 35 patients with high grade chondrosarcoma). Informative weighted coefficients were determined separately for ‘learning’ and ‘examination’ samples. On the basis of weighted coefficients, the decisive rule was created for differentiation between low-grade and high-grade chondrosarcoma. Results. The sensitivity of the method was 87.0%, specificity was 95.6%, total correct classification was 91.03%. Conclusion. Magnetic resonance imaging is a highly informative method for prediction of chondrosarcoma grade at the pre-surgery examination.
About the Authors
A. V. Fedorova
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow
Russian Federation
Moscow
N. V. Kochergina
National Medical Research Centre of Oncology n.a. N.N. Blokhin; Russian Medical Academy of Continuous Professional Education
Russian Federation
Moscow
Russian Federation
Moscow
A. B. Bludov
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow
Russian Federation
Moscow
I. V. Boulycheva
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow
Russian Federation
Moscow
E. A. Sushentsov
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow
Russian Federation
Moscow
O. G. Spirina
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow
Russian Federation
Moscow
Ya. A. Shchipakhina
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow
Russian Federation
Moscow
A. S. Nered
Medscan Co.
Russian Federation
Moscow
Russian Federation
Moscow
References
1. Douis H. The imaging of cartilaginous bone tumours. II. Chondrosarcoma. H. Douis, A. Saifuddin. Skeletal Radiol. 2013. Vol. 42 (5). P. 611–626.
2. Fletcher C, Bridge J, Hogendoorn P, Mertens F, eds.: WHO Classification of Tumors of Soft Tissue and Bone, 4th edn. Lyon: IARC; 2013.
3. Geirnaerdt M.J. Cartilaginous tumors: correlation of gadolinium-enhanced MR imaging and histopathologic findings. M.J. Geirnaerdt, J.L. Bloem, F. Eulderink et al. Radiology. 1993. Vol. 186 (3). P. 813.–817.
4. Gelderblom H. The clinical approach towards chondrosarcoma. H. Gelderblom, P. C. Hogendoorn, S.D. Dijkstra et al. Oncologist. 2008. Vol. 13 (3). P. 320.–329.
5. Janzen L. Intramedullary chondroid tumors of bone: correlation of abnormal peritumoral marrow and soft-tissue MRI signal with tumor type. L. Janzen, P.M. Logan, J.X. O’Connell et al. Skeletal Radiol. 1997. Vol. 26 (2). P. 100–106.
6. Konishi E. Primary central chondrosarcoma of long bone, limb girdle and trunk: Analysis of 174 cases by numerical scoring on histology. E. Konishi, Y. Nakashima, M. Mano et al. Pathol. Int. 2015. Vol. 65 (9). P. 468–475.
7. Varma D.G. Chondrosarcoma: MR imaging with pathologic correlation. D.G. Varma, A.G. Ayala, C.H. Carrasco et al. Radiographics. 1992. Vol. 12 (4). P. 687–704.
8. Yoo H. J. Differentiating high-grade from lowgrade chondrosarcoma with MR imaging. H.J. Yoo, S. H. Hong, J. Y. Choi et al. Eur. Radiol. 2009. Vol. 19 (12). P. 3008–3014. DOI: 10.1007/s00330–009–1493–4.
9. Нейштадт Э. Л. Опухоли и опухолеподобные заболевания костей. Э.Л. Нейштадт, А.Б. Маркочев. М.: Фолиант, 2007. 344 с.
Review
For citations:
Fedorova A.V., Kochergina N.V., Bludov A.B., Boulycheva I.V., Sushentsov E.A., Spirina O.G., Shchipakhina Ya.A., Nered A.S. Role of magnetic resonance imaging in prediction of chondrosarcoma of bone grade. Medical alphabet. 2020;(38):21-24. (In Russ.) https://doi.org/10.33667/2078-5631-2020-38-21-24
Views:
392
Email this article 