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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-762</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Физико-дозиметрическое планирование в стереотаксической лучевой терапии рака поджелудочной железы</article-title><trans-title-group xml:lang="en"><trans-title>Physico-dosimetric planning in stereotactic radiation therapy for pancreatic cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Назаренко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nazarenko</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Знаткова</surname><given-names>Я. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Znatkova</surname><given-names>Ya. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ллиева</surname><given-names>С. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Aliyeva</surname><given-names>S. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачев</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkachyov</surname><given-names>S. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ клинической и экспериментальной радиологии ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre of Oncology n.a. N. N. Blokhin</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>19</day><month>09</month><year>2018</year></pub-date><volume>2</volume><issue>29</issue><issue-title>Диагностика и онкотерапия</issue-title><fpage>49</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Назаренко А.В., Знаткова Я.Р., Ллиева С.Б., Ткачев С.И., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Назаренко А.В., Знаткова Я.Р., Ллиева С.Б., Ткачев С.И.</copyright-holder><copyright-holder xml:lang="en">Nazarenko A.V., Znatkova Y.R., Aliyeva S.B., Tkachyov S.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/762">https://www.med-alphabet.com/jour/article/view/762</self-uri><abstract><p>Стереотаксическая лучевая терапия представляет собой относительно новую разработку в области лучевой терапии. Дозиметрическое планирование такого вида лучевого лечения имеет свою специфику. Специализированное трехмерное планирование ЛТ позволяет достичь высокой дозы внутри мишени и высокого градиента дозы за пределами мишени. Представлены результаты сравнения двух методик физико-дозиметрического планирования сеансов лучевой терапии с модуляцией интенсивности пучка фотонов пациентов с раком поджелудочной железы.</p></abstract><trans-abstract xml:lang="en"><p>Stereotactic radiotherapy is a relatively new development in the field of radiation therapy. Dosimetric planning of this type of radiation treatment has its own specifics. Specialized three-dimensional planning of RT allows achieving a high dose inside the target and a high dose gradient outside the target. The results of a comparison of two methods for physico-dosimetric planning of radiotherapy sessions with modulation of the intensity of the photon beam of patients with pancreatic cancer are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стереотаксическая лучевая терапия</kwd><kwd>физико-дозиметрическое планирование</kwd><kwd>метод Монте-Карло</kwd></kwd-group><kwd-group xml:lang="en"><kwd>IMRT</kwd><kwd>VMAT</kwd><kwd>stereotactic radiation therapy</kwd><kwd>IMRT</kwd><kwd>VMAT</kwd><kwd>physico-dosimetric planning</kwd><kwd>Monte Carlo method</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cheung M. R., Tucker S. L., Dong L., de Crevoisier R., et al. Investigation of bladder dose and volume factors influencing lateurinary toxicity after external beam radiotherapy for prostate cancer. //Int. J. Radiat. Oncol. Biol. 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