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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-676</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Профилактическая терапия мигрени: от клинических рекомендаций к клинической практике</article-title><trans-title-group xml:lang="en"><trans-title>Preventive migraine therapy: from clinical recommendations to clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филатова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Filatova</surname><given-names>E. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Латышева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Latysheva</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет имени И. М. Сеченова (Сеченовский университет)» Минздрава России; ООО «Цефалголог» - Клиника головной боли и вегетативных расстройств имени академика А. Вейна</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Moscow State Medical University n.a. I. M. Sechenov; Clinic of headache and vegetative disorders named after academician A. Vein</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>03</day><month>06</month><year>2018</year></pub-date><volume>2</volume><issue>17</issue><issue-title>Неврология и психиатрия</issue-title><fpage>43</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Филатова Е.Г., Латышева Н.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Филатова Е.Г., Латышева Н.В.</copyright-holder><copyright-holder xml:lang="en">Filatova E.G., Latysheva N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/676">https://www.med-alphabet.com/jour/article/view/676</self-uri><abstract><p>В статье обсуждаются показания и основные принципы профилактической терапии мигрени. Показано, что выбор средства для медикаментозной профилактики основан на знании результатов РКИ, а также особенностей действия назначаемых препаратов, возможных побочных эффектах и возможностях их преодоления и наличии тех или иных комобидных мигрени заболеваний. Приоритет имеет профилактическая монотерапия, направленная на урежение дней с головной болью и лечение коморбидного расстройства.</p></abstract><trans-abstract xml:lang="en"><p>The article reviews indications and basic principles of migraine preventive treatment. Preventative drug selection should be based on the evidence from randomized clinical trials, the drug's mode of action and potential adverse events, as well as migraine comorbidities. Monotherapy is preferable and should be aimed at reducing headache frequency and treatment of comorbid conditions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мигрень</kwd><kwd>профилактика мигрени</kwd><kwd>лечение мигрени</kwd></kwd-group><kwd-group xml:lang="en"><kwd>migraine</kwd><kwd>prevention of migraine</kwd><kwd>treatment of migraine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Артеменко А. Р., Куренков А. А., Антипова О. С. «Диагностика и лечение хронической мигрени». Москва. Горячая линия - Телеком, 2014, 206 с.</mixed-citation><mixed-citation xml:lang="en">Артеменко А. Р., Куренков А. А., Антипова О. С. «Диагностика и лечение хронической мигрени». Москва. 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