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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-632</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Рационализация адъювантной химиотерапии рака ободочной кишки</article-title><trans-title-group xml:lang="en"><trans-title>Rationalization of adjuvant chemotherapy for colon cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Доброва</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dobrova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisova</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуторов</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Gutorov</surname><given-names>S. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>Л. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>L. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии имени Н. Н. Блохина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Oncology named after N. N. Blokhin</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>16</day><month>05</month><year>2018</year></pub-date><volume>1</volume><issue>15</issue><issue-title>Диагностика и онкотерапия</issue-title><fpage>12</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Доброва Н.В., Борисова Е.И., Гуторов С.Л., Жукова Л.Г., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Доброва Н.В., Борисова Е.И., Гуторов С.Л., Жукова Л.Г.</copyright-holder><copyright-holder xml:lang="en">Dobrova N.V., Borisova E.I., Gutorov S.L., Zhukova L.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/632">https://www.med-alphabet.com/jour/article/view/632</self-uri><abstract><p>На основании новых данных клинических исследований рассматриваются вопросы о рациональной длительности адъювантной терапии рака ободочной кишки в зависимости от стадии и молекулярных характеристик опухоли. Представленные результаты потенциально влияют на клиническое решение при выборе режима и оптимального срока адъювантного лечения.</p></abstract><trans-abstract xml:lang="en"><p>Basing on new clinical trials data, the optimal duration of colon cancer adjuvant therapy is considered depending on molecular characteristics and pathologic tumor staging. The presented results potentially influence the clinical decision on chemotherapy regimen choice and optimal duration of adjuvant treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак ободочной кишки</kwd><kwd>адъювантная химиотерапия</kwd><kwd>длительность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colon cancer</kwd><kwd>adjuvant chemotherapy</kwd><kwd>duration</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Andre T., Boni C., Navarro M., et al. 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