<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2026-20-153-157</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-5262</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Исследование динамики уровня потери клинического прикрепления у пациентов с хроническим пародонтитом после консервативной терапии</article-title><trans-title-group xml:lang="en"><trans-title>Investigation of the dynamics of the level of clinical attachment loss in patients with chronic periodontitis after conservative therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-5660-9276</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шастин</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shastin</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шастин Евгений Николаевич – к.м.н., главный врач.</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Evgeny N. Shastin – PhD in Medical Sciences, Chief Physician.</p><p>Krasnodar</p></bio><email xlink:type="simple">bracet@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2938-3063</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зюлькина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ziulkina</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зюлькина Лариса Алексеевна – д.м.н., доцент, декан факультета стоматологии, заведующий кафедрой стоматологии Медицинского института.</p><p>Пенза</p></bio><bio xml:lang="en"><p>Larisa A. Ziulkina – Doctor of Medical Sciences, Associate Professor, Dean of the Faculty of Dentistry, Head of the Department of Dentistry, Medical Institute.</p><p>Penza</p></bio><email xlink:type="simple">larisastom@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5678-1104</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефремова Анастасия Владимировна – к.м.н., доцент кафедры стоматологии Медицинского института.</p><p>Пенза</p></bio><bio xml:lang="en"><p>Anastasia V. Efremova – PhD in Medical Sciences, Associate Professor of the Department of Dentistry, Medical Institute.</p><p>Penza</p></bio><email xlink:type="simple">nastasya.efremova.87@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-2392-9478</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макбол</surname><given-names>А. А.О.</given-names></name><name name-style="western" xml:lang="en"><surname>Makbol</surname><given-names>A. A.O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Макбол Адел Али Омар – ассистент кафедры стоматологии Медицинского института.</p><p>Пенза</p></bio><bio xml:lang="en"><p>Adel A.O. Makbol – Assistant of the Department of Dentistry, Medical Institute.</p><p>Penza</p></bio><email xlink:type="simple">adel_makboul@hotmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8440-6598</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левашова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Levashova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Левашова Ольга Анатольевна – к.б.н., доцент кафедры медицинской микробиологии и лабораторной медицины.</p><p>Пенза</p></bio><bio xml:lang="en"><p>Olga A. Levashova – PhD in Biological Sciences, Associate Professor of the Department of Medical Microbiology and Laboratory Medicine.</p><p>Penza</p></bio><email xlink:type="simple">olga.lewashowa@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Стоматологическая клиника «БАЛЬДАР»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>BALDAR Dental Clinic</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Пензенский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Пензенский институт усовершенствования врачей – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza Institute for Further Training of Physicians – Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuous Professional Education»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>11</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>20</issue><issue-title>Стоматология (3)</issue-title><fpage>153</fpage><lpage>157</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шастин Е.Н., Зюлькина Л.А., Ефремова А.В., Макбол А.А., Левашова О.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Шастин Е.Н., Зюлькина Л.А., Ефремова А.В., Макбол А.А., Левашова О.А.</copyright-holder><copyright-holder xml:lang="en">Shastin E.N., Ziulkina L.A., Efremova A.V., Makbol A.A., Levashova O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/5262">https://www.med-alphabet.com/jour/article/view/5262</self-uri><abstract><p>Цель. Определить эффективность нехирургического пародонтологического лечения в зависимости от локализации участков потери клинического прикрепления у пациентов с хроническим генерализованным пародонтитом средней степени тяжести. Материалы и методы. Выполнено обследование и лечение 30 пациентов со средней степенью тяжести хронического генерализованного пародонтита в возрасте от 44 до 59 лет. Пациентам проводили санацию полости рта, консервативное пародонтологическое лечение. В соответствии с целью исследования, основной задачей являлось измерение степени потери клинического прикрепления (ПКП) до лечения и через 1 год после начала терапии. Уровень ПКП определяли пародонтальным зондом в шести точках около каждого зуба: в дистально-щечной (Т1), щечной (Т2), медиально-щечной (Т3), медиально-небной/язычной (Т4), небной/язычной (Т5), дистально-небной/язычной (Т6) точках. Всего в динамике было обследовано 5052 точек. Результаты. Через 1 год наихудшие результаты при проведении консервативного пародонтологического лечения у пациентов с хроническим генерализованным пародонтитом (средняя степень тяжести) получены в дистальных отделах (дистально-небные и дистально-язычные точки) моляров верхней и нижней челюстей. В области премоляров и фронтальных зубов консервативное лечение в большинстве случаев приводит к стабилизации уровня клинического прикрепления и улучшению состояния тканей пародонтального комплекса. Выводы. Неблагоприятный прогноз для дистальных отделов моляров обусловлен, по всей вероятности, совокупностью анатомических предпосылок (сложная морфология корней и фуркаций) и физических барьеров (низкая эргономичность доступа как для врача, так и для пациента, несимметричностью гигиенических мероприятий с правой и левой сторон), что в итоге приводит к невозможности полной элиминации микробной биопленки и создает условия для рецидива воспаления. Полученные результаты следует учитывать при планировании пародонтологического лечения и во избежание неблагоприятных исходов терапии включать хирургические методы в комплекс лечебных мероприятий. Неблагоприятную локализацию очагов пародонтального поражения (дистально-небные и дистально-язычные точки моляров верхней и нижней челюстей) целесообразно считать одним из предикторов прогрессирования заболевания.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To determine the effectiveness of non-surgical periodontal treatment depending on the localization of areas of loss of clinical attachment in patients with chronic generalized periodontitis of moderate severity. Materials and methods. 30 patients with moderate severity of chronic generalized periodontitis aged from 44 to 59 years were examined and treated. The patients underwent oral sanitation and conservative periodontal treatment. In accordance with the purpose of the study, the main task was to measure the degree of loss of clinical attachment (PKP) before treatment and 1 year after the start of therapy. The level of PKP was determined with a periodontal probe at six points near each tooth: distal-buccal (T1), buccal (T2), medial-buccal (T3), medial-palatine/lingual (T4), palatine/lingual (T5), distal-palatine/lingual (T6) points. A total of 5,052 points were examined in dynamics. Results. After 1 year, the worst results in conservative periodontal treatment in patients with chronic generalized periodontitis (moderate severity) were obtained in the distal sections (distal palatine and distal lingual points) of the molars of the upper and lower jaws. In the area of premolars and frontal teeth, conservative treatment in most cases leads to stabilization of the level of clinical attachment and improvement of the condition of the periodontal complex tissues. Conclusions. The unfavorable prognosis for the distal molars is most likely due to a combination of anatomical prerequisites (complex morphology of roots and furcations) and physical barriers (low ergonomics of access for both the doctor and the patient, asymmetry of hygiene measures on the right and left sides), which ultimately leads to the impossibility of complete elimination of microbial biofilm and creates conditions for recurrence of inflammation. The results obtained should be taken into account when planning periodontal treatment and, in order to avoid adverse treatment outcomes, include surgical methods in the complex of therapeutic measures. Unfavorable localization of periodontal lesions (distal palatine and distal lingual points of the molars of the upper and lower jaws) should be considered one of the predictors of disease progression.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический пародонтит</kwd><kwd>пародонтальные карманы</kwd><kwd>пародонтологическое лечение</kwd><kwd>потеря клинического прикрепления</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic periodontitis</kwd><kwd>periodontal pockets</kwd><kwd>periodontal treatment</kwd><kwd>loss of clinical attachment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ghezzi C., Ferrantino L., Donghi C., Vaghi S., Viganò V., Costa D., Mandaglio M., Pispero A., Lodi G. Clinical Audit of Minimally Invasive Nonsurgical Techniques in Active Periodontal Therapy. J Contemp Dent Pract. 2020;21(4):431–437.</mixed-citation><mixed-citation xml:lang="en">Ghezzi C., Ferrantino L., Donghi C., Vaghi S., Viganò V., Costa D., Mandaglio M., Pispero A., Lodi G. Clinical Audit of Minimally Invasive Nonsurgical Techniques in Active Periodontal Therapy. J Contemp Dent Pract. 2020;21(4):431–437.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Fernandez M.D.S., Martins T.M., Meza-Mauricio J., Ribeiro M.C., Silva F.H., Casarin M., Muniz F.W.M.G. Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review. Eur J Oral Sci. 2025;133(2):e70002. https://doi.org/10.1111/eos.70002.</mixed-citation><mixed-citation xml:lang="en">Fernandez M.D.S., Martins T.M., Meza-Mauricio J., Ribeiro M.C., Silva F.H., Casarin M., Muniz F.W.M.G. Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review. Eur J Oral Sci. 2025;133(2):e70002. https://doi.org/10.1111/eos.70002.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Castro Dos Santos N., Westphal M.R., Retamal-Valdes B., Duarte P.M., Figueiredo L.C., Faveri M., Shibli J., Soares G., Miranda T., Fermiano D., Borges I., Goncalves C., Tanaka C.J., Teles F., Goodson M., Hasturk H., Van Dyke T., Ehmke B., Eickholz P., Nickles K., Schlagenhauf U., Meyle J., Kocher T., Kim T.S., Doyle H., Feres M. Influence of gender on periodontal outcomes: A retrospective analysis of eight randomized clinical trials. J Periodontal Res. 2024;59(6):1175–1183. https://doi.org/10.1111/jre.13272.</mixed-citation><mixed-citation xml:lang="en">Castro Dos Santos N., Westphal M.R., Retamal-Valdes B., Duarte P.M., Figueiredo L.C., Faveri M., Shibli J., Soares G., Miranda T., Fermiano D., Borges I., Goncalves C., Tanaka C.J., Teles F., Goodson M., Hasturk H., Van Dyke T., Ehmke B., Eickholz P., Nickles K., Schlagenhauf U., Meyle J., Kocher T., Kim T.S., Doyle H., Feres M. Influence of gender on periodontal outcomes: A retrospective analysis of eight randomized clinical trials. J Periodontal Res. 2024;59(6):1175–1183. https://doi.org/10.1111/jre.13272.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Xu Y.J., Zhao L., Wu Y.F., Duan D.Y. Clinical study of periodontal endoscope-assisted subgingival scaling in the treatment of residual pocket. Hua Xi Kou Qiang Yi Xue Za Zhi. 2021;39(4):441–446. https://doi.org/10.7518/hxkq.2021.04.010.</mixed-citation><mixed-citation xml:lang="en">Xu Y.J., Zhao L., Wu Y.F., Duan D.Y. Clinical study of periodontal endoscope-assisted subgingival scaling in the treatment of residual pocket. Hua Xi Kou Qiang Yi Xue Za Zhi. 2021;39(4):441–446. https://doi.org/10.7518/hxkq.2021.04.010.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Herrera D., Sanz M., Kebschull M., Jepsen S., Sculean A., Berglundh T., Papapanou P.N., Chapple I., Tonetti M.S. EFP Workshop Participants and Methodological Consultant. Treatment of stage IV periodontitis: The EFP S3 level clinical practice guideline. J Clin Periodontol. 2022;49(24):4–71. https://doi.org/10.1111/jcpe.13639.</mixed-citation><mixed-citation xml:lang="en">Herrera D., Sanz M., Kebschull M., Jepsen S., Sculean A., Berglundh T., Papapanou P.N., Chapple I., Tonetti M.S. EFP Workshop Participants and Methodological Consultant. Treatment of stage IV periodontitis: The EFP S3 level clinical practice guideline. J Clin Periodontol. 2022;49(24):4–71. https://doi.org/10.1111/jcpe.13639.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Галиева А.С., Давидович Н.В., Оправин А.С., Башилова Е.Н., Рюмин К.Р., Бажукова Т.А. Результаты комплексной пародонтальной терапии с применением комбинации бактериофага и пробиотического препарата. Пародонтология. 2024;29(1):92–101. https://doi.org/10.33925/1683-3759-2024-821</mixed-citation><mixed-citation xml:lang="en">Galieva A.S., Davidovich N.V., Opravin A.S., Bashilova E.N., Ryumin K.R., Bazhukova T.A. The efficacy of bacteriophage/probiotic combination therapy in periodontal treatment. Parodontologiya. 2024;29(1):92–101. (In Russ.) https://doi.org/10.33925/1683-3759-2024-821.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Кейцлер М.И., Слажнева Е.С., Островская И.Г., Атрушкевич В.Г. Роль взаимодействия микробиоты и эпителиального барьера в патогенезе воспалительных заболеваний пародонта: систематический обзор. Пародонтология.2024;29(4):366–377.</mixed-citation><mixed-citation xml:lang="en">Keitsler M.I., Slazhneva E.S., Ostrovskaya I.G., Atrushkevich V.G. The role of microbiota and epithelial barrier interaction in the pathogenesis of periodontal diseases: a systematic review. Parodontologiya. 2024;29(4):366–377. (In Russ.) https://doi.org/10.33925/1683-3759-2024-1013</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Булгакова А.И., Солдатова Е.С., Кувардина Ю.О. Оптимизация комплексного лечения хронического пародонтита. Пародонтология. 2023;28(4):431–436. https://doi.org/10.33925/1683-3759-2023-840</mixed-citation><mixed-citation xml:lang="en">Bulgakov A.I., Soldatova E.S., Kuvardina Y.O. Optimization of chronic periodontitis comprehensive treatment. Parodontologiya. 2023;28(4):431–436. (In Russ.) https://doi.org/10.33925/1683-3759-2023-840</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Петров А.А. Изучение воздействия употребления кофе и курения сигарет на полость рта и ткани пародонта. Пародонтология. 2021;26(3):245–250. https://doi.org/10.33925/1683-3759-2021-26-3-245-250.</mixed-citation><mixed-citation xml:lang="en">Petrov A.A. Investigating the impact of coffee consumption and cigarette smoking in the oral cavity and periodontal tissues. Parodontologiya. 2021;26(3):245–250. (In Russ.) https://doi.org/10.33925/1683-3759-2021-26-3-245-250.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bartha V., Mohr J., Krumm B., Herz M.M., Wolff D., Petsos H. Minimal periodontal basic care – no surgery, no antibiotics, low adherence. What can be expected? A retrospective data analysis. Quintessence Int. 2022;53(8):666–675. https://doi.org/10.3290/j.qi.b3149423.</mixed-citation><mixed-citation xml:lang="en">Bartha V., Mohr J., Krumm B., Herz M.M., Wolff D., Petsos H. Minimal periodontal basic care – no surgery, no antibiotics, low adherence. What can be expected? A retrospective data analysis. Quintessence Int. 2022;53(8):666–675. https://doi.org/10.3290/j.qi.b3149423.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Saminsky M., Halperin-Sternfeld M., Machtei E.E., Horwitz J. Variables affecting tooth survival and changes in probing depth: a long-term follow-up of periodontitis patients. J Clin Periodontol. 2015;42(6):513-9. https://doi.org/10.1111/jcpe.12419.</mixed-citation><mixed-citation xml:lang="en">Saminsky M., Halperin-Sternfeld M., Machtei E.E., Horwitz J. Variables affecting tooth survival and changes in probing depth: a long-term follow-up of periodontitis patients. J Clin Periodontol. 2015;42(6):513-9. https://doi.org/10.1111/jcpe.12419.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Herz M.M., Hoffmann N., Braun S., Lachmann S., Bartha V., Petsos H. Periodontal pockets: Predictors for site-related worsening after non-surgical therapy-A long-term retrospective cohort study. J Clin Periodontol. 2024;51(6):680–690. https://doi.org/10.1111/jcpe.13957.</mixed-citation><mixed-citation xml:lang="en">Herz M.M., Hoffmann N., Braun S., Lachmann S., Bartha V., Petsos H. Periodontal pockets: Predictors for site-related worsening after non-surgical therapy-A long-term retrospective cohort study. J Clin Periodontol. 2024;51(6):680–690. https://doi.org/10.1111/jcpe.13957.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Bumm C.V., Gaenesch S., Nagler F., Frasheri I., Schwendicke F., Pitchika V, Ern C., Heym R., Wetzel C., Folwaczny M., Werner N. Endpoints of Periodontal Therapy in Elderly Patients With Stage III/IV Periodontitis and Their Oral Health-Related Quality of Life Following 2610 Years of Supportive Periodontal Therapy. J Clin Periodontol. 2025;52(10):1398–1409. https://doi.org/10.1111/jcpe.14198.</mixed-citation><mixed-citation xml:lang="en">Bumm C.V., Gaenesch S., Nagler F., Frasheri I., Schwendicke F., Pitchika V, Ern C., Heym R., Wetzel C., Folwaczny M., Werner N. Endpoints of Periodontal Therapy in Elderly Patients With Stage III/IV Periodontitis and Their Oral Health-Related Quality of Life Following 2610 Years of Supportive Periodontal Therapy. J Clin Periodontol. 2025;52(10):1398–1409. https://doi.org/10.1111/jcpe.14198.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Mensi M., Sordillo A., Marchetti S., Calza S., Scotti E. Clinical Comparison of Guided Biofilm Therapy and Scaling and Root Planing in the Active Phase of Periodontitis Management. Eur J Dent. 2025;19(2):482–492. https://doi.org/10.1055/s-0044-1791221.</mixed-citation><mixed-citation xml:lang="en">Mensi M., Sordillo A., Marchetti S., Calza S., Scotti E. Clinical Comparison of Guided Biofilm Therapy and Scaling and Root Planing in the Active Phase of Periodontitis Management. Eur J Dent. 2025;19(2):482–492. https://doi.org/10.1055/s-0044-1791221.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Бебарс А., Романо Ф., Джирауди М., Орту В., Секка И., Массано Е., Мариани Г.М., Айметти М. Влияние стресса на клинические исходы безоперационной пародонтальной терапии у пациентов с тяжелым генерализованным пародонтитом. Пародонтология. 2021;26(1):28–32. https://doi.org/10.33925/1683-3759-2021-26-1-28-32.</mixed-citation><mixed-citation xml:lang="en">Bebars A., Romano F., Giraudi M., Ortu V., Sekka I., Massano E, Mariani G.M., Aimetti M. Impact of stress on clinical outcomes of non-surgical periodontal therapy in patients with severe generalized periodontitis. Parodontologiya. 2021;26(1):28–32. (In Russ.) https://doi.org/10.33925/1683-3759-2021-26-1-28-32.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
