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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-508</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Изучение антимикробной активности композитных материалов</article-title><trans-title-group xml:lang="en"><trans-title>Study of antimicrobial activity of composite materials</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брагунова</surname><given-names>Р. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bragunova</surname><given-names>R. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Разумова</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Razumova</surname><given-names>S. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мелкумян</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Melkumyan</surname><given-names>A. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Браго</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Brago</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хасханова</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khaskhanova</surname><given-names>L. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорян</surname><given-names>И. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoryan</surname><given-names>I. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафронова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Safronova</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>People’s Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ г. Москвы «Городская клиническая больница имени Ф. И. Иноземцева» Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital n.a. F. I. Inozemtsev</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>19</day><month>01</month><year>2018</year></pub-date><volume>1</volume><issue>2</issue><issue-title>Стоматология</issue-title><fpage>54</fpage><lpage>58</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Брагунова Р.М., Разумова С.Н., Мелкумян А.Р., Браго А.С., Хасханова Л.М., Григорян И.Э., Сафронова О.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Брагунова Р.М., Разумова С.Н., Мелкумян А.Р., Браго А.С., Хасханова Л.М., Григорян И.Э., Сафронова О.В.</copyright-holder><copyright-holder xml:lang="en">Bragunova R.M., Razumova S.N., Melkumyan A.R., Brago A.S., Khaskhanova L.M., Grigoryan I.E., Safronova O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/508">https://www.med-alphabet.com/jour/article/view/508</self-uri><abstract><p>Добавление соединений хлоргексидина ацетата к композитному материалу способно повысить его антимикробные свойства и снизить риск развития вторичного кариеса. Для оценки антимикробной активности были получены образцы композитного материала с антимикробной добавкой путем добавления различных количеств хлоргексидина ацетата в композитную пасту. Исследование показало, что добавление хлоргексидина ацетата в состав композитного материала Реставрин привело к увеличению антимикробных свойств композитного материала.</p></abstract><trans-abstract xml:lang="en"><p>The addition of chlorhexidine acetate compounds to composite material can increase its antimicrobial properties and reduce the risk of secondary caries. In order to evaluate the antimicrobial activity, samples of composite material containing an antimicrobial additive were prepared by adding various amounts of chlorhexidine acetate to the composite paste. The study showed that the addition of chlorhexidine acetate to the composite material Restavrin increased its antimicrobial properties.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>композитный материал</kwd><kwd>хлоргексидина ацетат</kwd><kwd>кариес</kwd><kwd>антимикробная добавка</kwd><kwd>штаммы микроорганизмов</kwd><kwd>сhlorhexidine acetate</kwd></kwd-group><kwd-group xml:lang="en"><kwd>composite material</kwd><kwd>caries</kwd><kwd>antimicrobial additive</kwd><kwd>microbial strains</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Разумова С. Н. Микробиоценоз полости рта у пациентов различных возрастных групп / Мороз А. Ф., Шатохина С. Н.//Журнал микробиологии, эпидемиологии и иммунобиологии.- 2008.-№ 3.- с. 74-76.</mixed-citation><mixed-citation xml:lang="en">Разумова С. Н. Микробиоценоз полости рта у пациентов различных возрастных групп / Мороз А. Ф., Шатохина С. Н.//Журнал микробиологии, эпидемиологии и иммунобиологии.- 2008.-№ 3.- с. 74-76.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Разумова С. Н. Оценка влияния антимикробной добавки на свойства композита / Гапочкина Л. Л., Брагунова Р. М., Браго А. С., Хасханова Л. М., Манвелян А. С.// Медицинский Алфавит.-2017.-№ 4.- с. 24-26.</mixed-citation><mixed-citation xml:lang="en">Разумова С. Н. Оценка влияния антимикробной добавки на свойства композита / Гапочкина Л. Л., Брагунова Р. М., Браго А. С., Хасханова Л. М., Манвелян А. С.// Медицинский Алфавит.-2017.-№ 4.- с. 24-26.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Разумова С. Н. Эффективность лечения кариозных поражений зубов стеклоиономерными цементами/ Хасханова Л. М., Разумова С. Н., Брагунова Р. М., Булгаков В. С. // Медицина и фармакология: современный взгляд на изучение актуальных проблем.- 2016.- с. 109-117.</mixed-citation><mixed-citation xml:lang="en">Разумова С. Н. Эффективность лечения кариозных поражений зубов стеклоиономерными цементами/ Хасханова Л. М., Разумова С. Н., Брагунова Р. М., Булгаков В. С. // Медицина и фармакология: современный взгляд на изучение актуальных проблем.- 2016.- с. 109-117.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Botelho M. G. Inhibitory effects on select oral bacteria of antibacterial agents incorporated in a glass ionomer cement. Caries Res. 2003; 37: 108-114.</mixed-citation><mixed-citation xml:lang="en">Botelho M. G. Inhibitory effects on select oral bacteria of antibacterial agents incorporated in a glass ionomer cement. Caries Res. 2003; 37: 108-114.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Castilho A. R., Duque C., Negrini T. de C., Sacono N. T., de Paula A. B., de Souza Costa C. A., et al. In vitro and in vivo investigation of the biological and mechanical behaviour of resin-modified glass-ionomer cement containing chlorhexidine. J Dent. 2013; 41: 155-163.</mixed-citation><mixed-citation xml:lang="en">Castilho A. R., Duque C., Negrini T. de C., Sacono N. T., de Paula A. B., de Souza Costa C. A., et al. In vitro and in vivo investigation of the biological and mechanical behaviour of resin-modified glass-ionomer cement containing chlorhexidine. J Dent. 2013; 41: 155-163.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chaffee B. W., Cheng A. Global research trends on early-life feeding practices and early childhood caries: a systematic review. J Oral Dis. 2014; 2014: 675-658.</mixed-citation><mixed-citation xml:lang="en">Chaffee B. W., Cheng A. Global research trends on early-life feeding practices and early childhood caries: a systematic review. J Oral Dis. 2014; 2014: 675-658.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ferracane JL. Resin composite - state of the art. Dental Materials, 2011; 27: 29-38.</mixed-citation><mixed-citation xml:lang="en">Ferracane JL. Resin composite - state of the art. Dental Materials, 2011; 27: 29-38.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Fontana M. Secondary caries and restoration replacement: an unresolved problem [Text] / M. Fontana, C. Gonzales-Cabezas // Compend. Contin. Educ. Dent.-2000.-Vol.21.-P. 15-18.</mixed-citation><mixed-citation xml:lang="en">Fontana M. Secondary caries and restoration replacement: an unresolved problem [Text] / M. Fontana, C. Gonzales-Cabezas // Compend. Contin. Educ. Dent.-2000.-Vol.21.-P. 15-18.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Frencken J.E., Imazato S., Toi C., Mulder J., Mickenautsch S., Takahashi Y., et al. Anti-bacterial effect of chlorhexidine-containing glass ionomer cement in vivo: a pilot study. Caries Res. 2007; 41: 102-107.</mixed-citation><mixed-citation xml:lang="en">Frencken J.E., Imazato S., Toi C., Mulder J., Mickenautsch S., Takahashi Y., et al. Anti-bacterial effect of chlorhexidine-containing glass ionomer cement in vivo: a pilot study. Caries Res. 2007; 41: 102-107.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Guo Y., Zhou H. D., Feng Y. Z. Effects of Hybrid Coat on shear bond strength of five cements: an in vitro study. J Adv Prosthodont. 2017; 9(6): 447-452.</mixed-citation><mixed-citation xml:lang="en">Guo Y., Zhou H. D., Feng Y. Z. Effects of Hybrid Coat on shear bond strength of five cements: an in vitro study. J Adv Prosthodont. 2017; 9(6): 447-452.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hoszek A., Ericson D. In vitro fluoride release and the antibacterial effect of glass ionomers containing chlorhexidine gluconate. Oper Dent. 2008; 33: 696-701.</mixed-citation><mixed-citation xml:lang="en">Hoszek A., Ericson D. In vitro fluoride release and the antibacterial effect of glass ionomers containing chlorhexidine gluconate. Oper Dent. 2008; 33: 696-701.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Hu J., Du X., Huang C., Fu D., Ouyang X., Wang Y. Antibacterial and physical properties of EGCG-containing glass ionomer cements. J Dent. 2013; 41: 927-34.</mixed-citation><mixed-citation xml:lang="en">Hu J., Du X., Huang C., Fu D., Ouyang X., Wang Y. Antibacterial and physical properties of EGCG-containing glass ionomer cements. J Dent. 2013; 41: 927-34.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Mjor L. A. Secondary caries: aliterature review with case reports [Text] / L. A. Mjor, F. Toffenetti // Quintessence Int.- 2000.- Vol.31. P. 165-179.</mixed-citation><mixed-citation xml:lang="en">Mjor L. A. Secondary caries: aliterature review with case reports [Text] / L. A. Mjor, F. Toffenetti // Quintessence Int.- 2000.- Vol.31. P. 165-179.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Siegrist В E, Brecx M C, Gusberti F A, Joss A, Lang N P. In vivo early human dental plaque formation on different supporting substances. A scanning electron microscopic and bacteriological study. // Clin. Oral. Implants Res., 1991.-p. 2, 38-46</mixed-citation><mixed-citation xml:lang="en">Siegrist В E, Brecx M C, Gusberti F A, Joss A, Lang N P. In vivo early human dental plaque formation on different supporting substances. A scanning electron microscopic and bacteriological study. // Clin. Oral. Implants Res., 1991.-p. 2, 38-46</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Takahashi Y., Imazato S, Kaneshiro A. V., Ebisu S., Frencken J. E., Tay F. R. Antibacterial effects and physical properties of glass-ionomer cements containing chlorhexidine for the ART approach. Dent Mater. 2006; 22: 647-652.</mixed-citation><mixed-citation xml:lang="en">Takahashi Y., Imazato S, Kaneshiro A. V., Ebisu S., Frencken J. E., Tay F. R. Antibacterial effects and physical properties of glass-ionomer cements containing chlorhexidine for the ART approach. Dent Mater. 2006; 22: 647-652.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Türkün L.S., Türkün M., Ertugrul F., Ates M., Brugger S. Long-term antibacterial effects and physical properties of a chlorhexidine-containing glass ionomer cement. J Esthet Restor Dent. 2008; 20:.29-44.</mixed-citation><mixed-citation xml:lang="en">Türkün L.S., Türkün M., Ertugrul F., Ates M., Brugger S. Long-term antibacterial effects and physical properties of a chlorhexidine-containing glass ionomer cement. J Esthet Restor Dent. 2008; 20:.29-44.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Yadiki J. V., Jampanapalli S. R., Konda S., Inguva H. C., Chimata V. K. Comparative Evaluation of the Antimicrobial Properties of Glass Ionomer Cements with and without Chlorhexidine Gluconate. Int J Clin Pediatr Dent. 2016; 9(2): 99-103.</mixed-citation><mixed-citation xml:lang="en">Yadiki J. V., Jampanapalli S. R., Konda S., Inguva H. C., Chimata V. K. Comparative Evaluation of the Antimicrobial Properties of Glass Ionomer Cements with and without Chlorhexidine Gluconate. Int J Clin Pediatr Dent. 2016; 9(2): 99-103.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Yap A. U., Khor E., Foo S. H. Fluoride release and antibacterial properties of new-generation tooth-colored restoratives. Oper Dent. 1999; 24: 297-305</mixed-citation><mixed-citation xml:lang="en">Yap A. U., Khor E., Foo S. H. Fluoride release and antibacterial properties of new-generation tooth-colored restoratives. Oper Dent. 1999; 24: 297-305</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
