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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2026-11-11-13</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-5073</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Особенности гериатрического статуса и синдрома астении у пациентов с фибрилляцией предсердий пожилого и старческого возраста</article-title><trans-title-group xml:lang="en"><trans-title>Characteristics of geriatric status and asthenia syndrome in elderly and senile patients with atrial fibrillation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-3009-5760</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трушникова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trushnikova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трушникова Мария Александровна, ассистент кафедры поликлинической терапии</p><p>Пермь</p></bio><bio xml:lang="en"><p>Trushnikova Maria A., assistant professor at Dept of Outpatient Therapy </p><p>Perm </p></bio><email xlink:type="simple">m-trushnikova08@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5980-2364</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корягина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Koryagina</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корягина Наталья Александровна, д.м.н. профессор кафедры поликлинической терапии</p><p>Пермь</p></bio><bio xml:lang="en"><p>Koryagina Natalya A., Dr Med Sci (habil.), professor at Dept of Outpatient Therapy </p><p>Perm </p></bio><email xlink:type="simple">nina11-85@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-4834-2905</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корягин</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Koryagin</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корягин Владимир Сергеевич, ординатор 1-го года обучения по специальности кардиология</p><p>Пермь</p></bio><bio xml:lang="en"><p>Koryagin Vladimir S., first-year resident in Cardiology </p><p>Perm </p></bio><email xlink:type="simple">vladimirkoryagin12@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-7674-4434</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авдеев Алексей Викторович, к.м.н., доцент кафедры поликлинической терапии</p><p>Пермь</p></bio><bio xml:lang="en"><p>Avdeev Aleksey V., PhD Med Sci, associate professor at Dept of Outpatient Therapy</p><p>Perm </p></bio><email xlink:type="simple">svenav@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1686-3885</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шулькина</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Shulkina</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шулькина Софья Григорьевна, д.м.н. профессор кафедры поликлинической терапии </p><p>Пермь</p></bio><bio xml:lang="en"><p>Shulkina Sofia G., Dr Med Sci (habil.), professor at Dept of Outpatient Therapy </p><p>Perm </p></bio><email xlink:type="simple">shulkina-s@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7411-6204</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Третьякова</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tretyakova</surname><given-names>Yu. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Третьякова Юлия Игоревна, к.м.н., доцент кафедры поликлинической терапии</p><p>Пермь</p></bio><bio xml:lang="en"><p>Tretyakova Yulia I., PhD Med Sci, associate professor at Dept of Outpatient Therapy</p><p>Perm </p></bio><email xlink:type="simple">tretyakovayi@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Пермский государственный медицинский университет имени академика Е.А. Вагнера» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Perm State Medical University named after Academician E.A. Wagner</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2026</year></pub-date><volume>1</volume><issue>11</issue><issue-title>Кардиология. Неотложная медицина (1)</issue-title><fpage>11</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трушникова М.А., Корягина Н.А., Корягин В.С., Авдеев А.В., Шулькина С.Г., Третьякова Ю.И., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Трушникова М.А., Корягина Н.А., Корягин В.С., Авдеев А.В., Шулькина С.Г., Третьякова Ю.И.</copyright-holder><copyright-holder xml:lang="en">Trushnikova M.A., Koryagina N.A., Koryagin V.S., Avdeev A.V., Shulkina S.G., Tretyakova Y.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/5073">https://www.med-alphabet.com/jour/article/view/5073</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. В сфере гериатрии фибрилляция предсердий и синдром старческой астении выделяются как две важные медико-социальные трудности. Взаимодействие этих состояний оказывает глубокое негативное влияние на перспективы выздоровления, способствует росту числа осложнений и делает процесс лечения пациентов более комплексным и сложным.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Сравнительная оценка компонентов астении у пациентов с фибрилляцией предсердий в зависимости от принадлежности к возрастной группе.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В наблюдательное исследование включено 267 пациентов с ФП, разделенных на две группы: группа 1 (n=120, возраст ≥75 лет) и группа 2 (n=147, возраст 60–74 года). Всем пациентам проведена комплексная гериатрическая оценка с использованием валидизированных опросников и инструментов: опросник «Возраст не помеха» (оценка отношения к старению), MoCA-тест (оценка когнитивных функций), Гериатрическая шкала депрессии (GDS‑15), индекс Бартела (оценка повседневной активности), Индекс тяжести инсомнии (ISI) и кистевая динамометрия (оценка мышечной силы). Статистический анализ проводился с использованием программы StatTech v. 4.11.1 (разработчик – ООО «Статтех», Россия).</p></sec><sec><title>Результаты</title><p>Результаты. Пациенты группы 1 (≥75 лет) по сравнению с группой 2 (60–74 года) продемонстрировали более негативное восприятие старения (6,0 [6,0–7,0] баллов против 5,0 [5,0–6,0]), выраженные когнитивные нарушения (MoCA: 19,0 [18,0–21,0] баллов против 23,0 [21,0–25,0]), признаки клинической депрессии (GDS‑15: 9,0 [7,0–9,0] баллов против 6,0 [5,0–7,5]), значительное ограничение повседневной активности (Бартел: 75,0 [60,0–90,0] баллов против 95,0 [95,0–100,0]), тяжелую инсомнию (ISI: 21,0 [16,0–22,0] баллов против 8,0 [8,0–15,0]) и снижение мышечной силы (24,0 [20,0–31,0] кг против 30,0 [27,0–39,5] кг).</p></sec><sec><title>Заключение</title><p>Заключение. В отличие от пожилых пациентов, у больных фибрилляцией предсердий в старческом возрасте (≥75 лет) наблюдается тяжелая полиморфная астения, затрагивающая психику, мышление, эмоции, повседневные функции и физическое состояние.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. In the field of geriatrics, atrial fibrillation and senile asthenia syndrom stand out as two important medical and social difficulties. The interaction of these conditions has a profound negative impact on the prospects of recovery, contributes to an increase in the number of complications and makes the process of treating patients more complex and complex.</p><p>The aim of the study was to compare the components of asthenia in patients with atrial fibrillation depending on age group.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. This observational study included 267 patients with AF, divided into two groups: Group 1 (n=120, aged ≥75 years) and Group 2 (n=147, aged 60–74 years). All patients underwent a comprehensive geriatric assessment using validated questionnaires and instruments: the «Age is not a hindrance» questionnaire (assessment of attitudes toward aging), the MoCA test (assessment of cognitive function), the Geriatric Depression Scale (GDS‑15), the Barthel Index (assessment of activities of daily living), the Insomnia Severity Index (ISI), and handgrip dynamometry (assessment of muscle strength). Statistical analysis was performed using StatTech v. 4.11.1 (developer – StatTech LLC, Russia).</p></sec><sec><title>Results</title><p>Results. Patients in Group 1 (≥75 years) compared with Group 2 (60–74 years) demonstrated a more negative perception of aging (6.0 [6.0–7.0] points vs. 5.0 [5.0–6.0]), severe cognitive impairment (MoCA: 19.0 [18.0–21.0] points vs. 23.0 [21.0–25.0]), signs of clinical depression (GDS‑15: 9.0 [7.0–9.0] points vs. 6.0 [5.0–7.5]), significant limitation of daily activities (Barthel: 75.0 [60.0–90.0] points vs. 95.0 [95.0–100.0]), severe insomnia (ISI: 21.0 [16.0–22.0] points vs. 8.0 [8.0–15.0]) and decreased muscle strength (24.0 [20.0–31.0] kg versus 30.0 [27.0–39.5] kg).</p></sec><sec><title>Conclusion</title><p>Conclusion. Unlike elderly patients, patients with atrial fibrillation in old age (≥75 years) experience severe polymorphic asthenia, affecting the psyche, thinking, emotions, daily functions, and physical condition.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>старческий возраст</kwd><kwd>гериатрическая оценка</kwd><kwd>астения (хрупкость)</kwd><kwd>когнитивные нарушения</kwd><kwd>инсомния</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>very old age</kwd><kwd>geriatric assessment</kwd><kwd>frailty</kwd><kwd>cognitive impairment</kwd><kwd>insomnia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hindricks G, Potpara T, Dagres N. et al. 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