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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2026-9-63-69</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-5059</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Эффективность нутритивной коррекции с использованием биологически активной добавки к пище «Коэнзим Q10 100 мг» у спортсменов-любителей</article-title><trans-title-group xml:lang="en"><trans-title>Effectiveness of nutritional correction using the dietary supplement “Coenzyme Q10 100 mg” in athletes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4689-3591</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орлова Светлана Владимировна, д. м. н., профессор, зав. кафедрой диетологии и клинической нутрициологии</p><p>AuthorID: 717867</p><p>Москва</p></bio><bio xml:lang="en"><p>Orlova Svetlana V., Dr Med Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology</p><p>AuthorID: 717867</p><p>Moscow</p></bio><email xlink:type="simple">orlova-sv@rudn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3220-0333</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитина Елена Александровна, к.м.н., доцент кафедры диетологии и клинической нутрициологии, ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); эксперт Методического аккредитационно-симуляционного центра, ФГБУ «Национальный медицинский исследовательский центр терапии и профилактической медицины» Минздрава России</p><p>Москва</p></bio><bio xml:lang="en"><p>Nikitina Elena A., PhD Med Sci, associate professor at Dept of Dietetics and Clinical Nutrition, Peoples’ Friendship University of Russia named after Patrice Lumumba; Expert at the Methodological Accreditation and Simulation Center, National Medical Research Center for Therapy and Preventive Medicine</p><p>Moscow</p></bio><email xlink:type="simple">nikitina-ea1@rudn.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4010-6315</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Выборная</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vybornaya</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Выборная Ксения Валерьевна, научный сотрудник лаборатории антропонутрициологии и спортивного питания</p><p>AuthorID: 735425</p><p>Москва</p></bio><bio xml:lang="en"><p>Vybornaya Ksenia V., researcher at the Laboratory of Anthroponutrition and Sports Nutrition Federal Research Centre of Nutrition, Biotechnology and Food Safety</p><p>AuthorID: <ext-link xlink:href="https://www.elibrary.ru/author_profile.asp?id=735425" ext-link-type="uri">735425</ext-link></p><p>Moscow</p></bio><email xlink:type="simple">dombim@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia named after Patrice Lumumba</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ФГБУ «Национальный медицинский исследовательский центр терапии и профилактической медицины» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia named after Patrice Lumumba; National Medical Research Center for Therapy and Preventive Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУН «Федеральный исследовательский центр питания, биотехнологии и безопасности пищи»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Research Centre of Nutrition, Biotechnology and Food Safety</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>01</day><month>06</month><year>2026</year></pub-date><volume>0</volume><issue>9</issue><issue-title>Диетология и нутрициология</issue-title><fpage>63</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Орлова С.В., Никитина Е.А., Выборная К.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Орлова С.В., Никитина Е.А., Выборная К.В.</copyright-holder><copyright-holder xml:lang="en">Orlova S.V., Nikitina E.A., Vybornaya K.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/5059">https://www.med-alphabet.com/jour/article/view/5059</self-uri><abstract><p>В статье обосновывается актуальность применения нутритивной поддержки, в частности биологически активных добавок к пище, для коррекции функционального состояния спортсменов-любителей в условиях интенсивных физических нагрузок. Особое внимание уделяется коэнзиму Q10 (Q10) – жирорастворимому соединению, которое играет ключевую роль в энергетическом обмене (синтез АТФ в митохондриях) и обладает антиоксидантными свойствами. Анализ литературы подтверждает, что экзогенный прием Q10 может способствовать повышению выносливости, снижению оксидативного стресса и повреждения мышечной ткани, а также оказывать кардиопротективное и иммуномодулирующее действие.</p><p>Целью данного исследования являлась оценка эффективности воздействия 30-дневного курса приема биологически активной добавки к пище «Коэнзим Q10100 мг» (ЗАО «Эвалар») на организм спортсменов-любителей.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В рандомизированном плацебо-контролируемом исследовании приняли участие 40 спортсменов (игровые виды спорта, возраст 20–28 лет, разделенных на две равные группы: основная группа (n=20) принимала Q10 по 100 мг/сут в течение 30 дней, группа сравнения (n=20) получала плацебо.Эффективность оценивалась на 15-й и 31-й день с помощью опросников самооценки, когнитивных тестов (таблицы Шульте), лабораторных анализов крови (общий и биохимический: КФК, КФК-МБ, тропонин Т, липидный профиль, СРБ), ЭКГ с нагрузкой и ЭхоКГ.</p></sec><sec><title>Основные результаты</title><p>Основные результаты. Субъективная оценка: в основной группе отмечено достоверное улучшение самочувствия: повысилась переносимость физических нагрузок (средний балл вырос с 6,1 до 7,3), ускорилось восстановление после тренировок (с 6,0 до 6,8), улучшилась готовность к следующим нагрузкам и качество пробуждения. В группе плацебо эти показатели оставались практически без изменений.</p></sec><sec><title>Лабораторные данные</title><p>Лабораторные данные. На фоне приема Q10 зафиксировано снижение уровня маркеров повреждения мышечной ткани (КФК снизился с 418 до 220 ед/л, КФК-МБ – с 43,8 до 25,8 ед/л), особенно выраженное у спортсменов с исходно повышенными значениями. В группе плацебо значимой динамики не наблюдалось.</p></sec><sec><title>Инструментальные данные</title><p>Инструментальные данные. При приеме Q10 у 70% спортсменов-любителей выявлен позитивный эффект в виде нормализации (30%) или улучшения (40%) процессов реполяризации миокарда по данным ЭКГ. Структурных изменений сердца по данным ЭхоКГ за время короткого курса не выявлено.</p></sec><sec><title>Безопасность</title><p>Безопасность: за время приема не зафиксировано аллергических реакций или побочных явлений.</p></sec><sec><title>Заключение</title><p>Заключение. Проведенное исследование продемонстрировало, что включение коэнзима Q10 в рацион спортсменов-любителей в дозировке 100 мг/сут на протяжении 30 дней является безопасным и эффективным методом нутритивной коррекции.</p></sec></abstract><trans-abstract xml:lang="en"><p>This article substantiates the relevance of using nutritional support, particularly dietary supplements, to improve the functional status of amateur athletes under intense physical activity. Particular attention is paid to coenzyme Q10 (ubiquinone), a fat-soluble compound that plays a key role in energy metabolism (ATP synthesis in mitochondria) and has antioxidant properties. A review of the literature conﬁrms that exogenous Q10 supplementation can help improve endurance, reduce oxidative stress and muscle damage, and exert cardioprotective and immunomodulatory effects.</p><sec><title>Materials and methods</title><p>Materials and methods. A randomized, placebo-controlled study involved 40 athletes, age 20–28 years divided into two equal groups: main group (n=20): received Q10 at 100 mg/day for 30 days. Comparison group (n=20): received a placebo. Effectiveness was assessed on days 15 and 31 using self-assessment questionnaires, cognitive tests (Schulte Tables), laboratory blood tests (complete blood count and biochemical analysis: CK, CK-MB, troponin T, lipid proﬁle, CRP), exercise ECG, and Echo-CG.</p></sec><sec><title>Main Results</title><p>Main Results. Subjective Assessment. The main group showed a signiﬁcant improvement in well-being: increased tolerance to physical exertion (mean score increased from 6.1 to 7.3), accelerated recovery after training (from 6.0 to 6.8), improved readiness for subsequent loads, and better waking quality. In the placebo group, these indicators remained virtually unchanged.</p></sec><sec><title>Laboratory Data</title><p>Laboratory Data. Q10 intake was associated with a decrease in the levels of markers of muscle tissue damage (CK decreased from 418 to 220 U/L, CK-MB from 43.8 to 25.8 U/L), particularly pronounced in athletes with initially elevated values. No signiﬁcant dynamics were observed in the placebo group.</p></sec><sec><title>Instrumental Data</title><p>Instrumental Data. In 70% of athletes taking Q10, a positive effect was observed in the form of normalization (30%) or improvement (40%) of myocardial repolarization processes according to ECG data. No structural changes in the heart were detected by Echo-CG during the short course.</p></sec><sec><title>Safety</title><p>Safety. No allergic reactions or adverse effects were recorded during the intake period.</p></sec><sec><title>Conclusion</title><p>Conclusion. This study demonstrated that incorporating coenzyme Q10 into the diet of junior athletes at a dosage of 100 mg/day for 30 days is a safe and effective method of nutritional correction.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>коэнзим Q10</kwd><kwd>убихинон</kwd><kwd>спортсмены-любители</kwd><kwd>нутритивная коррекция</kwd><kwd>физическая работоспособность</kwd><kwd>восстановление</kwd><kwd>антиоксидантная защита</kwd><kwd>креатинфосфокиназа (КФК)</kwd><kwd>повреждение миокарда</kwd><kwd>оксидативный стресс</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Coenzyme Q10</kwd><kwd>ubiquinone</kwd><kwd>amateur athletes</kwd><kwd>nutritional correction</kwd><kwd>physical performance</kwd><kwd>recovery</kwd><kwd>antioxidant protection</kwd><kwd>creatine phosphokinase (CPK)</kwd><kwd>myocardial damage</kwd><kwd>oxidative stress</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Paquot N. 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