medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2026-5-16-24medalphabet-5014Research ArticleСтатьиПрофилактический и лечебный потенциал дентабиотиков при патологии пародонта и сопутствующих заболеваниях кишечника и печениPreventive and therapeutic potential of dentabiotics in periodontal pathology and concomitant intestinal and liver diseaseshttps://orcid.org/0000-0002-1597-1876ТруханД. И.TrukhanD. I.

Трухан Дмитрий Иванович, д. м. н., доцент, проф. кафедры поликлинической терапии и внутренних болезней

Омск

Trukhan Dmitry I., Dr Med Sci (habil.), professor at Dept of Polyclinic Therapy and Internal Diseases

Omsk

dmitry_trukhan@mail.ruhttps://orcid.org/0009-0004-3249-3425СулимовА. Ф.SulimovA. F.

Сулимов Анатолий Филиппович, д. м. н., проф., зав. кафедрой челюстно-лицевой хирургии

Омск

Sulimov Anatoly F., Dr Med Sci (habil.), professor, head of Dept of Maxillofacial Surgery

Omsk

afsulimov@yandex.ruhttps://orcid.org/0000-0002-4721-6605ТруханЛ. Ю.TrukhanL. Yu.

Трухан Лариса Юрьевна, к. м. н., врач-стоматолог, кафедра челюстно-лицевой хирургии

Омск

Trukhan Larisa Yu., PhD Med Sci, dentist at Dept of Maxillofacial Surgery

Omsk

larissa_trukhan@mail.ruhttps://orcid.org/0000-0002-7695-149XРожковаМ. Ю.RozhkovaM. Yu.

Рожкова Мария Юрьевна, к. м. н., доцент кафедры поликлинической терапии и внутренних болезней

Омск

Rozhkova Maria Yu., PhD Med Sci, associate professor at Dept of Polyclinic Therapy and Internal Diseases

Omsk

marroj@mail.ruhttps://orcid.org/0000-0003-1481-8842ГолошубинаВ. В.GoloshubinaV. V.

Голошубина Виктория Владимировна, к. м. н., доцент кафедры поликлинической терапии и внутренних болезней

Омск

Goloshubina Victoria V., PhD Med Sci, associate professor at Dept of Polyclinic Therapy and Internal Disease

Omsk

vikulka03@mail.ruФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииРоссияOmsk State Medical UniversityRussian Federation20260505202605Гастроэнтерология и диетология (1)1624Copyright © Трухан Д.И., Сулимов А.Ф., Трухан Л.Ю., Рожкова М.Ю., Голошубина В.В., 20262026Трухан Д.И., Сулимов А.Ф., Трухан Л.Ю., Рожкова М.Ю., Голошубина В.В.Trukhan D.I., Sulimov A.F., Trukhan L.Y., Rozhkova M.Y., Goloshubina V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/5014

Микробиота полости рта оказывает определенное влияние на развитие и течение гастроэнтерологических заболеваний, в частности, неалкогольной жировой болезни печени и воспалительных заболеваний кишечника. Подтверждением концепции «пародонтальной медицины» и двунаправленной взаимосвязи заболеваний пародонта и соматических заболеваний является наличие эффекта от лечения одного заболевания, который сопровождается позитивным влиянием на другое заболевание. В первой части обзора рассмотрено влияние нехирургического парадонтологического лечения на течение неалкогольной жировой болезни печени и воспалительных заболеваний кишечника. Во второй части обзора рассмотрены возможности использования пробиотиков как дополнительного компонента нехирургического парадонтологического лечения. Пробиотики, применяемые для коррекции нарушений микробиоценоза и поддержания нормальной микрофлоры полости рта, называются дентабиотиками. Рассмотрены состав и терапевтические возможности компонентов двух дентабиотиков компании «БиоМэджик» позволяющие предполагать наличие профилактического и лечебного потенциала дентабиотиков при патологии пародонта и сопутствующих заболеваниях кишечника и печени по оси «рот–кишечник–печень». Возможное позитивное влияние дентабиотиков на микробиоту верхних дыхательных путей и ЛОР-органов позволяет рассматривать их в качестве дентаоробиотиков – пробиотиков для коррекции нарушений микробиоценоза и поддержания нормальной микрофлоры полости рта, верхних дыхательных путей и ЛОР-органов.

The oral microbiota has a significant impact on the development and course of gastrointestinal diseases, particularly non-alcoholic fatty liver disease and inflammatory bowel disease. The concept of «periodontal medicine» and the bidirectional relationship between periodontal and somatic diseases is supported by the fact that the treatment of one disease has a positive effect on the other. The first part of this review examines the impact of non-surgical periodontal treatment on the course of non-alcoholic fatty liver disease and inflammatory bowel disease. The second part of the review examines the potential of using probiotics as an adjunct to non-surgical periodontal treatment. Probiotics used to correct microbiome imbalances and maintain normal oral microflora are called dentobiotics. The composition, composition, and therapeutic potential of two dentobiotics from BioMagic are discussed. These properties suggest the potential for preventive and therapeutic use in treating periodontal disease and associated intestinal and liver diseases along the mouth-intestine-liver axis. The potential positive impact of dentobiotics on the microbiota of the upper respiratory tract and ENT organs suggests that they can be considered dentarobiotics – probiotics for correcting microbiome imbalances and maintaining normal microflora in the oral cavity, upper respiratory tract, and ENT organs.

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The authors declare that there are no conflicts of interest present.