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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2026-10-22-27</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4982</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Ассоциация групп крови системы АВ0, статуса секретора и резус-фактора с восприимчивостью к пародонтиту и кариесу зубов: результаты анализа научных исследований</article-title><trans-title-group xml:lang="en"><trans-title>Association of AB0 blood groups, secretor status, and rhesus factor with susceptibility to periondontitis and dental caries: results of an analysis of modern research</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-6595-2189</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виталий Игоревич Котов, старший преподаватель</p><p>кафедра стоматологии последипломного образования</p><p>Самара</p></bio><bio xml:lang="en"><p>Vitaliy I. Kotov, Senior Lecturer</p><p>Department of Postgraduate Education in Dentistry</p><p>Samara</p></bio><email xlink:type="simple">v.i.kotov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1630-7050</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буланов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Bulanov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Иванович Буланов, д.м.н., проф., ректор</p><p>Москва</p></bio><bio xml:lang="en"><p>Sergey I. Bulanov, DM Sci, prof., rector</p><p>Moscow</p></bio><email xlink:type="simple">glvrssp2@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-5920-2390</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лысов</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lysov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитрий Николаевич Лысов, к. м.н., доцент</p><p>кафедра стоматологии последипломного образования</p><p>Самара</p></bio><bio xml:lang="en"><p>Dmitriy N. Lysov, PhD, Associate Professor</p><p>Department of Postgraduate Education in Dentistry</p><p>Samara</p></bio><email xlink:type="simple">lysov.d.92@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-2934-2020</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Софронов</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sofronov</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матвей Витальевич Софронов, к. м. н., доцент, декан</p><p>стоматологический факультет</p><p>Москва</p></bio><bio xml:lang="en"><p>Matvey V. Sofronov, PhD, Associate Professor, Dean</p><p>Faculty of Dentistry</p><p>Moscow</p></bio><email xlink:type="simple">sofronovmed@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ЧУОО ВО «Медицинский университет «Реавиз»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical University «Reaviz»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ЧУОО ВО «Московский Медицинский университет «Реавиз»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Medical University «Reaviz»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>02</day><month>05</month><year>2026</year></pub-date><volume>0</volume><issue>10</issue><issue-title>Стоматология (2)</issue-title><fpage>22</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Котов В.И., Буланов С.И., Лысов Д.Н., Софронов М.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Котов В.И., Буланов С.И., Лысов Д.Н., Софронов М.В.</copyright-holder><copyright-holder xml:lang="en">Kotov V.I., Bulanov S.I., Lysov D.N., Sofronov M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4982">https://www.med-alphabet.com/jour/article/view/4982</self-uri><abstract><sec><title>   Актуальность</title><p>   Актуальность. Пародонтит и кариес – это заболевания, связанные с множеством факторов, где генетическая предрасположенность играет существенную роль. Группы крови системы AB0 и статус секретора считаются потенциальными маркерами, но сведения об их корреляции с болезнями зубов и пародонта носят противоречивый характер.</p></sec><sec><title>   Цель</title><p>   Цель. Выполнить детальный анализ имеющихся научных данных о корреляции между группами крови системы AB0, статусом секретора, резус-фактором, разными проявлениями пародонтита и кариеса.</p></sec><sec><title>   Материалы и методы</title><p>   Материалы и методы. Для подготовки обзора проведен поиск и анализ научных публикаций в базах данных PubMed, eLibrary, CyberLeninka и Google Scholar за период с 1971 по 2025 годы. В анализ включено 30 исследований, посвященных изучению связи групп крови АВ0, статуса секретора и резус-фактора с распространенностью, тяжестью течения и патогенетическими механизмами пародонтита и кариеса.</p></sec><sec><title>   Результаты</title><p>   Результаты. Установлено, что характер корреляции зависит от типа заболевания и особенностей исследуемой группы людей. Хронический пародонтит с большей вероятностью встречается у людей с первой группой крови (0), а агрессивному пародонтиту подвергаются носители второй (А) или третьей (В) группы крови. Помимо вышеперечисленных данных, необходимо учитывать статус секретора АВ0. Благодаря наличию статуса секретора концентрация кариесогенных бактерий (Streptococcus mutans) в полости рта ниже на 20–30 %. Вместе с тем, подобная связь не наблюдается в отношении пародонтита, однако изученные научные исследования подтвердили, что резус-фактор группы крови влияет на вероятность появления данного заболевания.</p></sec><sec><title>   Вывод</title><p>   Вывод. Группы крови системы АВ0 и статус секретора являются существенными генетическими факторами в отношении заболеваний зубов и пародонта, но их влияние зависит от множества аспектов: этнических, иммунологических, микробиологических и прочих. Данное исследование показало, что при выборе метода лечения необходимо учитывать групповую принадлежность и статус секретора АВ0.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>   Background</title><p>   Background. Periodontitis and caries are diseases associated with multiple factors, in which genetic predisposition plays a significant role. AB0 blood groups and secretor status are considered potential markers, but data on their correlation with dental and periodontal diseases are contradictory.</p></sec><sec><title>   Objective</title><p>   Objective. To conduct a detailed analysis of existing scientific data on the correlation between AB0 blood groups, secretor status, Rhesus factor, and various manifestations of periodontitis and caries.</p></sec><sec><title>   Materials and methods</title><p>   Materials and methods. To prepare the review, a search and analysis of scientific publications was conducted in the PubMed, eLibrary, CyberLeninka, and Google Scholar databases for the period from 1971 to 2025. The analysis included 30 studies devoted to the study of the relationship between ABO blood groups, secretory status, and Rh factor with the prevalence, severity, and pathogenetic mechanisms of periodontitis and caries.</p></sec><sec><title>   Results</title><p>   Results. It was found that the nature of the correlation depends on the type of disease and the characteristics of the population studied. Thus, chronic periodontitis is more likely to occur in people with blood type 0 (0), while aggressive periodontitis is more common in people with blood types A and B. In addition to the above data, AB0 secretor status must be taken into account. Due to the presence of AB0 secretor status, the concentration of cariogenic bacteria (Streptococcus mutans) in the oral cavity is 20-30 % lower. However, a similar relationship is not observed for periodontitis; however, the studies reviewed confirmed that the Rh factor of the blood type influences the likelihood of developing this disease.</p></sec><sec><title>   Conclusion</title><p>   Conclusion. AB0 blood groups and secretory status are significant genetic factors in dental and periodontal diseases, but their influence depends on many factors, including ethnicity, immunology, microbiology, and others. This study demonstrated that blood group membership and AB0 secretory status must be considered when choosing a treatment method.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>система группы АВ0</kwd><kwd>статус секретора</kwd><kwd>резус-фактор</kwd><kwd>хронический пародонтит</kwd><kwd>агрессивный пародонтит</kwd><kwd>кариес</kwd></kwd-group><kwd-group xml:lang="en"><kwd>AB0 blood group system</kwd><kwd>secretory status</kwd><kwd>Rh factor</kwd><kwd>chronic periodontitis</kwd><kwd>aggressive periodontitis</kwd><kwd>сaries</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Papapanou PN, Sanz M, Buduneli N, et al. Periodontitis: Consensus report of work-group 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018;89 Suppl 1:S173–S182. 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