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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2026-6-7-10</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4936</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Напряжение сдвига стенки и индекс колебания после каротидной эндартерэктомии в послеоперационном периоде</article-title><trans-title-group xml:lang="en"><trans-title>Wall shear stress and oscillatory shear index after carotid endarterectomy in the postoperative period</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1535-5982</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сандриков</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavrilenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сандриков Валерий Александрович – д.м.н., проф., академик РАН, руководитель отдела клинической физиологии, инструментальной и лучевой диагностики НКЦ № 1</p><p>Москва</p></bio><bio xml:lang="en"><p>Gavrilenko Alexander Vasilyevich – Academician of the Russian Academy of Sciences, MD, Professor, Head of the Department of Vascular Surgery of the Scientific and Clinical Center No. 1</p><p>Moscow</p></bio><email xlink:type="simple">sandrikov@med.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4840-0607</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дутикова</surname><given-names>Е. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Dutikova</surname><given-names>E. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дутикова Елена Федоровна – к.м.н., ведущий научный сотрудник, лаборатории электрофизиологии и нагрузочных тестов отдела клинической физиологии, инструментальной и лучевой диагностики НКЦ № 1</p><p>Москва</p></bio><bio xml:lang="en"><p>Dutikova Elena Fedorovna – PHD, Leading Researcher of Laboratory of Electrophysiology and Stress Tests of the Department of Clinical Physiology, Instrumental and Radiation Diagnostics of the Scientific and Clinical Center No. 1</p><p>Moscow</p></bio><email xlink:type="simple">dutikova@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7267-7369</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гавриленко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sandrikov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гавриленко Александр Васильевич – д.м.н., проф., академик РАН, заведующий отделением хирургии сосудов научно-клинического центра № 1</p><p>Москва</p></bio><bio xml:lang="en"><p>Sandrikov Valery Alexandrovich – MD, Professor, Academician of the Russian Academy of Sciences, Head of Clinical Physiology Department and Clinical Center No.1</p><p>Moscow</p></bio><email xlink:type="simple">a.v.gavrilenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6165-6474</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулагина</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulagina</surname><given-names>T. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кулагина Татьяна Юрьевна – д.м.н., зав. лаб. электрофизиологии и нагрузочных тестов отдела клинической физиологии, инструментальной и лучевой диагностики НКЦ №1</p><p>Москва</p></bio><bio xml:lang="en"><p>Kulagina Tatiana Yurievna – MD, Head of the Laboratory of Electrophysiology and Stress Tests of the Department of Clinical Physiology, Instrumental and Radiation Diagnostics of the Scientific and Clinical Center No. 1</p><p>Moscow</p></bio><email xlink:type="simple">takula@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8118-2552</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жигулина</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhigulina</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жигулина Ольга Андреевна – младший научный сотрудник, врач функциональной диагностики лаборатории электрофизиологии и нагрузочных тестов отдела клинической физиологии, инструментальной и лучевой диагностики НКЦ 1</p><p>Москва</p></bio><bio xml:lang="en"><p>Zhigulina Olga Andreevna – junior research assistant, doctor of functional diagnostics of the Laboratory of Electrophysiology and Stress Tests of the Department of Clinical Physiology, Instrumental and Radiation Diagnostics of the Scientific and Clinical Center No.1</p><p>Moscow</p></bio><email xlink:type="simple">ol.bulkina2016@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6202-8506</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камалов</surname><given-names>Ю. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamalov</surname><given-names>Yu. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Камалов Юлий Рафаэльевич – д.м.н., зав. лаб. ультразвуковой диагностики отдела клинической физиологии, инструментальной и лучевой диагностики НКЦ1</p><p>Москва</p></bio><bio xml:lang="en"><p>Kamalov Yuliy Rafaelevich – MD, Head of the Ultrasound Laboratory of the Department of Clinical Physiology, Instrumental and Radiation Diagnostics of the Scientific and Clinical Center No. 1</p><p>Moscow</p></bio><email xlink:type="simple">kamalov53@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зобов</surname><given-names>К. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zоbov</surname><given-names>K. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зобов Кирилл Игоревич – младший научный сотрудник отделения хирургии сосудов НКЦ 1</p><p>Москва</p></bio><bio xml:lang="en"><p>Zоbov Kiril Igorevich – Junior Researcher at the Department of Vascular Surgery of the Clinical Center No. 1</p><p>Moscow</p></bio><email xlink:type="simple">kirill-zobo@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГНЦ РФ ФГБНУ «Российский научный центр хирургии им. академика Б.В. Петровского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Scientific Institution Petrovsky National Rеsеаrсh Сеntrе of Surgery (FSBSI Petгovsky NRCS NCC1)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>13</day><month>04</month><year>2026</year></pub-date><volume>0</volume><issue>6</issue><issue-title>Современная функциональная диагностика (1)</issue-title><fpage>7</fpage><lpage>10</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сандриков В.А., Дутикова Е.Ф., Гавриленко А.В., Кулагина Т.Ю., Жигулина О.А., Камалов Ю.Р., Зобов К.И., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Сандриков В.А., Дутикова Е.Ф., Гавриленко А.В., Кулагина Т.Ю., Жигулина О.А., Камалов Ю.Р., Зобов К.И.</copyright-holder><copyright-holder xml:lang="en">Gavrilenko A.V., Dutikova E.F., Sandrikov V.A., Kulagina T.Y., Zhigulina O.A., Kamalov Y.R., Zоbov K.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4936">https://www.med-alphabet.com/jour/article/view/4936</self-uri><abstract><p>Цель. Оценить изменения напряжения сдвига стенки внутренней сонной артерии (ВСА) после каротидной эндартерэктомии (КЭАЭ) в отдаленном послеоперационном периоде. Материал и методы исследования. С патологией ВСА до операции обследовано 26 пациентов (65±2,9 года), в среднем степень стеноза составляла 80,4±3,3 % (64–95%). По эхогенности распределение бляшек было следующим: преимущественно гипоэхогенные – 12, гиперэхогенные – 10, изоэхогенные – 4. После операции каротидной эндартерэктомии (КЭАЭ) в госпитальном периоде удовлетворительная эхолокация позволила провести исследование у 19 пациентов (61,6±2,7 года). В отдаленном периоде через 6–14 месяцев обследовано 12 пациентов (63,1±2,0 года). Исследование проводились на ультразвуковом сканере Mindray Resona 7 (Китай), линейным датчиком (2,5–9 МГц) в режиме V-flow. Оценивали систолическую скорость кровотока (Vs), напряжение сдвига стенки (WSS), турбулентность кровотока по векторному анализу до и после стеноза. Изменение направления вектора WSS в течение сердечного цикла описывали с помощью индекса колебания (Oscillatory Shear Index, OSI). Был рассчитан внутригрупповой коэффициент корреляции при измерении напряжения и сдвига стенки.Результаты. До операции для стеноза ВСА характерно изме нение WSS в различных участках артерии и повышенная турбулентность кровотока. Адекватность операции КАЭА оценивали по динамике изменения скорости кровотока и отношению напряжения сдвига стенки к проксимальному и дистальному руслу. В отдаленном послеоперационном периоде направление и скорости векторов потока приближаются к нормальным значениям, что служит одним из оценочных гемодинамических показателей адекватности хирургической коррекции стеноза ВСА.Заключение. Критериями адекватной коррекции считали нормализацию внутрисосудистых потоков крови, напряжения сдвига стенки и индекса колебания, снижения турбулентности кровотока. Регистрация напряжения сдвига стенки с помощью V-flow у пациентов с цереброваскулярными заболеваниями представляет собой новое направление для оценки результатов хирургического лечения.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To evaluate changes in the shear stress of the internal carotid artery (ICA) wall after carotid endarterectomy (CEAE) in the remote postoperative period. Material and methods of the study. 26 patients (65±2.9 years old) with ICA pathology were examined before surgery, with an average degree of stenosis of 80.4±3.3% (64–95%). According to echogenicity, the distribution of plaques was as follows: predominantly hypoechoic – 12, hyperechoic – 10, and isoechoic – 4. After carotid endarterectomy (CEAE) in the hospital period, satisfactory echolocation allowed for the examination of 19 patients (61.6±2.7 years). In the long-term period, 12 patients (63.1±2.0 years) were examined 6–14 months later. The study was conducted using a Mindray Resona 7 ultrasound scanner (China) and a linear sensor (2.5–9 MHz) in V-flow mode. Systolic blood f low velocity (Vs), wall shear stress (WSS), and blood flow turbulence were assessed using vector analysis before and after stenosis. The change in the direction of the WSS vector during the cardiac cycle was described using the Oscillatory Shear Index (OSI). The intra-group correlation coefficient was calculated for the measurement of wall stress and shear. Results. Before surgery, ICA stenosis is characterized by changes in WSS in different parts of the artery and increased blood flow turbulence. The adequacy of the CAEA operation was assessed based on the dynamics of changes in blood flow velocity and the ratio of wall shear stress to the proximal and distal vessels. In the long-term postoperative period, the direction and velocity of the flow vectors approach normal values, which serves as one of the hemodynamic indicators of the adequacy of surgical correction of ICA stenosis. Conclusion. The criteria for adequate correction were the normalization of intravascular blood flow, wall shear stress, and oscillation index, as well as the reduction of blood flow turbulence. The registration of wall shear stress using V-flow in patients with cerebrovascular diseases represents a new approach for evaluating the results of surgical treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>скорость кровотока</kwd><kwd>напряжение сдвига стенки</kwd><kwd>индекс колебания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>blood flow rate</kwd><kwd>wall shear stress</kwd><kwd>oscillation shear index</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Yiemeng Hoi, Bruce A Wasserman, Yuanyuan J Xie, et al. // Characterization of volumetric flow rate waveforms at the carotid bifurcations of older adults. Physiological Measurement, 31(3):291–302, March 2010. 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