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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-35-34-45</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4770</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Роль неинвазивной респираторной поддержки на разных этапах лечения гипоксемической острой дыхательной недостаточности. Часть II</article-title><trans-title-group xml:lang="en"><trans-title>The role of non-invasive respiratory support at different stages of acute hypoxemic respiratory failure treatment. Part II</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5477-4242</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корякин</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Koryakin</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корякин Альберт Геннадьевич, зав. отделением анестезиологии-реанимации; ассистент кафедры анестезиологии, реаниматологии и неотложноймедицины</p></bio><bio xml:lang="en"><p>Koryakin Albert G., head of Intensive Care Unit; assistant at Dept of Anesthesiology, Reanimatology and Emergency Medicine</p></bio><email xlink:type="simple">koriakinalbert@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4535-2563</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Власенко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vlasenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Власенко Алексей Викторович, д.м.н., зав. отделением анестезиологииреанимации; зав. кафедрой анестезиологии, реаниматологии и неотложноймедицины</p></bio><bio xml:lang="en"><p>Vlasenko Aleksey V., DM Sci (habil.), associate professor, head of Depat of Anesthesiology, Reanimatology and Emergency Medicine</p></bio><email xlink:type="simple">dr.vlasenko67@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1050-0415</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клюев</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kluev</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клюев Иван Сергеевич, врач-анестезиолог-реаниматолог отделения анестезиологии-реанимации; ассистент кафедры анестезиологии,реаниматологии и неотложной медицины</p></bio><bio xml:lang="en"><p>Kluev Ivan S., anesthesiologisr-rescusitator in Intensive Care Unit1; assistant at Dept of Anesthesiology, Reanimatology and Emergency Medicine</p></bio><email xlink:type="simple">ivan.kluev11@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3852-8877</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родионов</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rodionov</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Родионов Евгений Петрович, к.м.н., доцент, зам. главного врача по анестезиологии-реаниматологии; доцент кафедры анестезиологии, реаниматологии и неотложной медицины</p></bio><bio xml:lang="en"><p>Rodionov Evgenyi P., PhD Med, associate professor, deputy chief physician for Anesthesiology and Intensive Care, associate pofessor at Dept of Anesthesiology, Reanimatology and Emergency Medicine</p></bio><email xlink:type="simple">dr.rodionov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евдокимов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Evdokimov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евдокимов Евгений Александрович, д.м.н., проф., проф. кафедры анестезиологии и неотложной медицины</p></bio><bio xml:lang="en"><p>Evdokimov Evgeniy A., DM Sci (habil.), professor, professor at Dept of Anesthesiology and Emergency Medicine</p></bio><email xlink:type="simple">ea_evdokimov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Московский многопрофильный научно-клинический центр им. С.П. Боткина Департамента здравоохранения г. Москвы»; Кафедра анестезиологии, реаниматологии и неотложной медицины ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center;  Anesthesiology, reanimatology and emergency medicine department of the Russian Medical Academy Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кафедра анестезиологии, реаниматологии и неотложной медицины ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Anesthesiology, reanimatology and emergency medicine department of the Russian Medical Academy Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>25</day><month>12</month><year>2025</year></pub-date><volume>0</volume><issue>35</issue><issue-title>Кардиология. Неотложная медицина (4)</issue-title><fpage>34</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Корякин А.Г., Власенко А.В., Клюев И.С., Родионов Е.П., Евдокимов Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Корякин А.Г., Власенко А.В., Клюев И.С., Родионов Е.П., Евдокимов Е.А.</copyright-holder><copyright-holder xml:lang="en">Koryakin A.G., Vlasenko A.V., Kluev I.S., Rodionov E.P., Evdokimov E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4770">https://www.med-alphabet.com/jour/article/view/4770</self-uri><abstract><p>Неинвазивная респираторная поддержка в последние годы заняла ключевое место в лечении гипоксемической острой дыхательной недостаточности. Современные методы респираторной поддержки – неинвазивная вентиляция легких и высокопоточная оксигенотерапия – широко применяются как при развитии гипоксемии, так и на этапе прекращения искусственной вентиляции легких при тяжелых формах дыхательной недостаточности. Наряду с большим количеством неоспоримых преимуществ одним из основных ограничений применения неинвазивной респираторной поддержки является своевременное выявление признаков ее неэффективности, показаний для интубации и риск задержки начала инвазивной респираторной поддержки. Во второй части настоящего обзора литературы мы систематизировали данные о возможностях и ограничениях неинвазивной вентиляции легких и высокопоточной оксигенотерапии, критериях оценки их клинической эффективности на этапах развития гипоксемической острой дыхательной недостаточности и прекращения искусственной вентиляции легких, в том числе у пациентов-канюленосителей.</p></abstract><trans-abstract xml:lang="en"><p>In recent years, noninvasive respiratory support has taken a key place in the hypoxemic acute respiratory failure treatment. Modern methods of respiratory support – noninvasive ventilation and high-flow oxygen therapy are widely used both in the hypoxemia development and at the stage of mechanical ventilation discontinuation at severe forms of respiratory failure. Along with many undeniable advantages, one of the main limitations of non-invasive respiratory support is the timely detection of signs of its ineffectiveness, indications for intubation, and the risk of delaying the initiation of invasive respiratory support. In the second part of this review, we systematized data on the possibilities and limitations of non-invasive lung ventilation and high-flow oxygen therapy, as well as the criteria for assessing their clinical effectiveness at the stages of developing hypoxemic acute respiratory failure and discontinuing mechanical ventilation, including in patients with cannulas.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гипоксемическая острая дыхательная недостаточность</kwd><kwd>респираторная поддержка</kwd><kwd>неинвазивная вентиляция легких</kwd><kwd>высокопоточная оксигенотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypoxemic acute respiratory failure</kwd><kwd>respiratory support</kwd><kwd>noninvasive ventilation</kwd><kwd>high-flow oxygen therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Рябов Г.А. Синдромы критических состояний / Г.А. Рябов. 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