medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2025-27-22-29medalphabet-4682Research ArticleСтатьиРоль неинвазивной респираторной поддержки на разных этапах лечения гипоксемической острой дыхательной недостаточности. Часть IThe role of non-invasive respiratory support at different stages of acute hypoxemic respiratory failure treatment. Part Ihttps://orcid.org/0000-0002-5477-4242КорякинА. Г.KoryakinA. G.

Корякин Альберт Геннадьевич, зав. отделением анестезиологии-реанимации; ассистент кафедры анестезиологии, реаниматологии и неотложной медицины, 

Москва.

Koryakin Albert G., Head of Intensive Care Unit; assistant at Dept of Anesthesiology, Reanimatology and Emergency Medicine,

Moscow.

koriakinalbert@gmail.comhttps://orcid.org/0000-0003-4535-2563ВласенкоА. В.VlasenkoA. V.

Власенко Алексей Викторович, д. м. н., зав. отделением анестезиологии-реанимации; зав. кафедрой анестезиологии, реаниматологии и неотложной медицины,

Москва.

Vlasenko Aleksey V., DM Sci (habil.), Associate Professor; Head of Dept of Anesthesiology, Reanimatology and Emergency Medicine,

Moscow.

dr.vlasenko67@mail.ruhttps://orcid.org/0000-0003-1050-0415КлюевИ. С.KluevI. S.

Клюев Иван Сергеевич, врач-анестезиолог-реаниматолог отделения анестезиологии-реанимации; ассистент кафедры анестезиологии, реаниматологии и неотложной медицины, 

Москва.

Kluev Ivan S., Anesthesiologist-Resuscitator in Intensive Care Unit; Assistant at Dept of Anesthesiology, Reanimatology and Emergency Medicine,

Moscow.

ivan.kluev11@gmail.comhttps://orcid.org/0000-0002-3852-8877РодионовЕ. П.RodionovE. P.

Родионов Евгений Петрович, к. м. н., доцент, зам. главного врача по анестезиологии-реаниматологии; доцент кафедры анестезиологии, реаниматологии и неотложной медицины,

Москва.

Rodionov Evgenyi P., PhD Med, Associate Professor, Deputy Chief Physician for Anesthesiology and Intensive Care; Associate Professor at Dept of Anesthesiology, Resuscitation and Emergency Medicine,

Moscow.

dr.rodionov@gmail.comЕвдокимовЕ. А.EvdokimovE. A.

Евдокимов Евгений Александрович, д. м. н., проф., проф. кафедры анестезиологии и неотложной медицины,

Москва.

Evdokimov Evgeniy A., DM Sci (habil.), Professor, Professor at Dept of Anesthesiology and Emergency Medicine,

Moscow.

ea_evdokimov@mail.ruГБУЗ «Московский многопрофильный научно-клинический центр им. С.П. Боткина Департамента здравоохранения г. Москвы»; Кафедра анестезиологии, реаниматологии и неотложной медицины ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияS.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center; Anesthesiology, Reanimatology and Emergency Medicine Department of the Russian Medical Academy Continuing Professional EducationRussian FederationКафедра анестезиологии, реаниматологии и неотложной медицины ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияAnesthesiology, Reanimatology and Emergency Medicine Department of the Russian Medical Academy Continuing Professional EducationRussian Federation202516112025027Кардиология. Неотложная медицина (3)2229Copyright © Корякин А.Г., Власенко А.В., Клюев И.С., Родионов Е.П., Евдокимов Е.А., 20252025Корякин А.Г., Власенко А.В., Клюев И.С., Родионов Е.П., Евдокимов Е.А.Koryakin A.G., Vlasenko A.V., Kluev I.S., Rodionov E.P., Evdokimov E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/4682

Тяжелая острая гипоксемическая дыхательная недостаточность остается одной из актуальных и прикладных проблем современной медицины и реаниматологии, так как является ведущей причиной развития критических состояний и высокой летальности. Согласно современным представлениям, особую роль в развитии и усугублении дыхательной недостаточности играет самоповреждение легких пациентом, которое может развиваться при патологической одышке и в условиях любого метода респираторной поддержки. Ряд исследований последних лет продемонстрировал существенную клиническую эффективность неинвазивной респираторной поддержки по сравнению с традиционной искусственной вентиляцией легких. Благодаря этому концепция лечения дыхательной недостаточности изменилась в пользу более активного применения неинвазивных респираторных технологий и высокопоточной оксигенотерапии. Однако их рациональное и персонифицированное использование остается трудоемкой задачей ввиду большого разнообразия этиологических факторов, механизмов патогенеза и полиморфизма клинических проявлений расстройств дыхания. Целью настоящей публикации является обзор научных данных по использованию методов неинвазивной респираторной поддержки на разных этапах лечения гипоксемической острой дыхательной недостаточности. В первой части будут рассмотрены актуальные механизмы развития самоповреждения легких пациентом и общие характеристики неинвазивной вентиляции легких и высокопоточной оксигенотерапии.

Treatment of hypoxemic acute respiratory failure remains one of the urgent and applied problems of modern intensive care, as it is the leading cause of critical conditions and high mortality in patients in intensive care units. Patient self-inflicted lung injury plays a special role in maintaining and worsening respiratory failure, which can develop under any method of respiratory support. A number of studies in recent years have demonstrated significant clinical effectiveness of non-invasive respiratory support compared to traditional mechanical ventilation. Due to this, the concept of respiratory failure treatment has changed in favor of more active use of non-invasive ventilation and high-flow oxygen therapy. However, their rational and personalized use remains a labor-intensive task due to the polymorphism of clinical manifestations, diversity of etiological factors and pathogenetic mechanisms of respiratory disorders. The purpose of this publication is to review the literature data on the use of non-invasive respiratory support methods at different stages of hypoxemic acute respiratory failure treatment.

The first part will consider the current mechanisms of development of patient self-inflicted lung injury and the general characteristics of noninvasive ventilation and high-flow oxygen therapy.

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The authors declare that there are no conflicts of interest present.