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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-27-18-21</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4681</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Искусственная вентиляция легких при малоинвазивных операциях коронарного шунтирования</article-title><trans-title-group xml:lang="en"><trans-title>Lung ventilation in minimal invasive direct coronary artery bypass surgery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2405-9368</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Толмачева</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tolmacheva</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Толмачева Надежда Николаевна, врач анестезиолог-реаниматолог,</p><p>Москва.</p></bio><bio xml:lang="en"><p>Tolmacheva Nadezhda N., аnesthesiologist,</p><p>Moscow.</p></bio><email xlink:type="simple">nadezda.tolmachova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8978-0394</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пшеничный</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pshenichnyy</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пшеничный Тимофей Андреевич, к. м. н., врач анестезиолог- реаниматолог,</p><p>Москва.</p></bio><bio xml:lang="en"><p>Pshenichnyy Timofey A., PhD Med, anesthesiologist,</p><p>Moscow.</p></bio><email xlink:type="simple">dr.pshenichniiy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4434-3123</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аксельрод</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Akselrod</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аксельрод Борис Альбертович, д. м. н., проф., врач анестезиолог-реаниматолог, зав. отделением анестезиологии-реанимации,</p><p>Москва.</p></bio><bio xml:lang="en"><p>Akselrod Boris A., DM Sci (habil.), professor, anesthesiologist, head of Dept of Cardioanesthesiology,</p><p>Moscow.</p></bio><email xlink:type="simple">7403797@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Российский научный центр хирургии им. акад. Б.В. Петровского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Petrovsky National Research Center of Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>16</day><month>11</month><year>2025</year></pub-date><volume>0</volume><issue>27</issue><issue-title>Кардиология. Неотложная медицина (3)</issue-title><fpage>18</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Толмачева Н.Н., Пшеничный Т.А., Аксельрод Б.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Толмачева Н.Н., Пшеничный Т.А., Аксельрод Б.А.</copyright-holder><copyright-holder xml:lang="en">Tolmacheva N.N., Pshenichnyy T.A., Akselrod B.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4681">https://www.med-alphabet.com/jour/article/view/4681</self-uri><abstract><sec><title>Введение</title><p>Введение. При проведении малоинвазивных операций коронарного шунтирования (КШ) обеспечение оксигенирующей функции легких является трудной задачей.</p></sec><sec><title>Цель</title><p>Цель: изучить возможность применения высокочастотной струйной вентиляции (ВЧВ) независимого легкого при проведении малоинвазивных операций КШ.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование вошло 69 пациентов. У 32 проводили однолегочную вентиляцию легких (ОВЛ), а у 37 – дифференцированную ОВЛ с ВЧВ независимого легкого. Проанализированы газовый состав артериальной крови, параметры искусственной вентиляции легких (ИВЛ) и метаболические маркеры. Оценили характер и частоту послеоперационных осложнений.</p></sec><sec><title>Результаты</title><p>Результаты. В группе ОВЛ+ВЧВ по сравнению с группой ОВЛ уровень напряжения кислорода в артериальной крови (PaO2) и соотношение РаО2/FiO2 было выше на всех этапах проведения ОВЛ. Количество пациентов с РаО2/FiO2≤200 в группе ОВЛ по сравнению с группой ОВЛ+ВЧВ было больше на этих же этапах. Не обнаружено разницы между группами в количестве послеоперационных осложнений, длительности ИВЛ и пребывания в отделении реанимации и интенсивной терапии (ОРИТ).</p></sec><sec><title>Заключение</title><p>Заключение. Применение дифференцированной ОВЛ с ВЧВ независимого легкого при малоинвазивных операциях КШ позволяет обеспечить лучшую оксигенирующую функцию легких, предупредить развитие гипоксемии и не приводит к увеличению количества послеоперационных осложнений.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Providing oxygenating lung function is a difficult task during minimal invasive direct coronary artery bypass surgery (MIDCAB).</p><p>The objective was to study the possibility of using high-frequency jet ventilation (HFJV) of an independent lung during MIDCAB operations.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 69 patients were examined. Single-lung ventilation (SLV) was performed in 32 patients, and differentiated SLV with HFJV of an independent lung was performed in 37 patients. The gas composition of arterial blood, parameters of artificial ventilation and metabolic markers were analyzed. The nature and frequency of postoperative complications were assessed.</p></sec><sec><title>Results</title><p>Results. In the SLV+HFJV group, compared with the SLV group, the level of oxygen tension in arterial blood (PaO2) and the PaO2/FiO2 ratio were higher at all stages of SLV. The number of patients with PaO2/FiO2 ≤200 in the OVL group compared to the OVL+HFV group was higher at the same stages. No difference was found between the groups in the number of postoperative complications, duration of artificial lung ventilation (ALV), and stay in the intensive care unit (ICU).</p></sec><sec><title>Conclusions</title><p>Conclusions. The use of differentiated OVL with HFJV of an independent lung in MIDCAB operations allows for better oxygenating function of the lungs, prevents the development of hypoxemia, and does not lead to an increase in the number of postoperative complications.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>однолегочная вентиляция легких</kwd><kwd>искусственная вентиляция легких</kwd><kwd>высокочастотная вентиляция легких</kwd><kwd>малоинвазивные операции коронарного шунтирования</kwd><kwd>анестезия у кардиохирургических больных.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Single-lung ventilation</kwd><kwd>artificial lung ventilation</kwd><kwd>high-frequency jet ventilation</kwd><kwd>cardiac surgery</kwd><kwd>minimal invasive direct coronary artery bypass surgery</kwd><kwd>cardiac anaesthesia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aston D., Zeloof D., Falter F. 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