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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-26-25-28</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4656</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Возможности интраоперационного контрастно-усиленного ультразвукового исследования затылочной глиобластомы: описание клинического случая</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of intraoperative contrast-enhanced ultrasound examination of occipital glioblastoma: a clinical case description</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-1976-7823</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дыщиров</surname><given-names>Ю. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Dyshchirov</surname><given-names>Yu. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дыщиров Юнус Юсуфович, аспирант, врач ультразвуковой диагностики отделения ультразвуковой диагностики</p><p>Москва</p></bio><bio xml:lang="en"><p>Dyshchirov Yunus Yu., postgraduate student, ultrasonic diagnostics doctor at Ultrasonic Diagnostics Dept.</p><p>Moscow</p></bio><email xlink:type="simple">dychshirov03@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3563-7293</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitina</surname><given-names>L. A</given-names></name></name-alternatives><bio xml:lang="ru"><p>Митина Лариса Анатольевна, д. м. н., в. н. с. отделения ультразвуковой диагностики</p><p>Москва</p></bio><bio xml:lang="en"><p>Mitina Larisa A., DM Sci (habil.), leading researcher at Ultrasonic Diagnostics Dept.</p><p>Moscow</p></bio><email xlink:type="simple">lmitina@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1905-9083</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitsev</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайцев Антон Михайлович, врач-онколог, нейрохирург, к. м. н., зав. нейрохирургическим отделением</p><p>Москва</p></bio><bio xml:lang="en"><p>Zaitsev Anton M., PhD Med, oncologist, neurosurgeon, head of Neurosurgical Dept.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанов</surname><given-names>С. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanov</surname><given-names>S. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Степанов Станислав Олегович, зав. отделением ультразвуковой диагностики</p><p>Москва</p></bio><bio xml:lang="en"><p>Stepanov Stanislav O., head of Ultrasound Diagnostics Dept.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0924-6245</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кирсанова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirsanova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кирсанова Ольга Николаевна, к. м. н., с. н. с., врач-онколог нейрохирургического отделения</p><p>Москва</p></bio><bio xml:lang="en"><p>Kirsanova Olga N., PhD Med, senior researcher, oncologist at Neurosurgical Dept.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>P. A. Herzen Oncology Research Institute – branch of National Medical Research Center of Radiology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>09</day><month>11</month><year>2025</year></pub-date><volume>0</volume><issue>26</issue><issue-title>Диагностика и онкотерапия (3)</issue-title><elocation-id>25‑28</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Дыщиров Ю.Ю., Митина Л.А., Зайцев А.М., Степанов С.О., Кирсанова О.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Дыщиров Ю.Ю., Митина Л.А., Зайцев А.М., Степанов С.О., Кирсанова О.Н.</copyright-holder><copyright-holder xml:lang="en">Dyshchirov Y.Y., Mitina L.A., Zaitsev A.M., Stepanov S.O., Kirsanova O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4656">https://www.med-alphabet.com/jour/article/view/4656</self-uri><abstract><p>Описан клинический случай интраоперационного контрастно-усиленного ультразвукового исследования (ИКУЗИ) опухоли головного мозга с применением контрастного препарата «Соновью». Метод позволил уточнить границы опухолевого поражения и оценить ангиоархитектонику глиобластомы, выявляемую при интраоперационном ультразвуковом исследовании (ИОУЗИ).</p></abstract><trans-abstract xml:lang="en"><p>A clinical case of intraoperative contrast-enhanced ultrasound (ICUSI) of a brain tumor using the contrast agent «Sonovyu» is described. The method allowed to clarify the boundaries of the tumor lesion and to evaluate the angioarchitectonics of glioblastoma revealed by intraoperative ultrasound (IOUSI).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>глиобластома</kwd><kwd>опухоль головного мозга</kwd><kwd>интраоперационное контрастно-ультразвуковое исследование</kwd><kwd>гистологическая верификация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>glioblastoma</kwd><kwd>brain tumor</kwd><kwd>intraoperative contrast-enhanced ultrasound</kwd><kwd>histological verifi</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dietrich C. F., Nolsøe C. P., Barr R. G., Berzigotti A. et al. Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) in the Liver – Update 2020 – WFUMB in Cooperation with EFSUMB, AFSUMB, AIUM, and FLAUS. Ultraschall Med. 2020; 41 (5): 562–585. 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