medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2025-24-42-49medalphabet-4641Research ArticleСтатьиВлияние типа реакции артериального давления на результаты ABCDE стресс-эхокардиографии с физической нагрузкойEffect of blood pressure response type on ABCDE stress echocardiography resultshttps://orcid.org/0000-0001-6586-7404ТимофееваТ. М.TimofeevaТ. M.

Тимофеева Татьяна Михайловна – к.м.н., доцент кафедры; врач отделения ультразвуковых и функциональных методов исследования

ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы», Медицинский институт, кафедра внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева

Москва

Tatiana M. Timofeeva – MD, PhD, associate professor at the Department; Doctor of the department of ultrasound and functional research method

Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev, Institute of Medicine, Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University

Moscow

timtan@bk.ruhttps://orcid.org/0000-0003-2412-5986СафароваА. Ф.SafarovaA. F.

Сафарова Айтен Фуад кызы – д.м.н., профессор кафедры; врач отделения ультразвуковых и функциональных методов исследования

ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы», Медицинский институт, кафедра внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева

Москва

Ayten F.  Safarova – MD, PhD, professor at the Department, Doctor of the department of ultrasound and functional research methods

Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev, Institute of Medicine, Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University

Moscow

aytensaf@mail.ruhttps://orcid.org/0000-0002-4389-9752ЕфимоваВ. П.EfimovaV. P.

Ефимова Виктория Павловна – к.м.н., доцент кафедры; заведующий отделением ультразвуковых и функциональных методов исследования

ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы», Медицинский институт, кафедра внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева

Москва

Victoria P. Efimova – MD, PhD, associate professor at the Department; Doctor of the department of ultrasound and functional research methods

Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev, Institute of Medicine, Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University

Moscow

efimovavp@rambler.ruОзоваЕ. М.OzovaE. M.

Озова Елена Меджидовна – к.м.н., ассистент кафедры; врач отделения ультразвуковых и функциональных методов исследования

ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы», Медицинский институт, кафедра внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева

Москва

Elena M. Ozova – MD, PhD, assistant of the Department; physician of the department of ultrasound and functional research methods

Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev, Institute of Medicine, Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University

Moscow

elenaozova@mail.ruФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы», Медицинский институт; Университетская клиническая больница имени В.В. Виноградова (филиал) ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы»РоссияInstitute of Medicine, Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University); Vinogradov University Clinical Hospital (branch) of the RUDN UniversityRussian Federation202507112025024Современная функциональная диагностика (3)4249Copyright © Тимофеева Т.М., Сафарова А.Ф., Ефимова В.П., Озова Е.М., 20252025Тимофеева Т.М., Сафарова А.Ф., Ефимова В.П., Озова Е.М.Timofeeva Т.M., Safarova A.F., Efimova V.P., Ozova E.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/4641Цель

Цель. Оценить частоту гипертонической реакции артериального давления (АД) на физическую нагрузку (ГРН) при проведении стресс-эхокардиографии (СЭ) у пациентов с известной или подозреваемой ишемической болезнью сердца и влияние ГРН на результаты ABCDE-СЭ.

Материалы и методы

Материалы и методы. В одноцентровое исследование включено 193 пациента, которым была выполнена ABCDE-СЭ (оценка нарушений локальной сократимости, В-линий, резервов сократительного (СР), коронарного, хронотропного) с традиционной оценкой реакции АД. Были изучены частота возникновения ГРН в ходе СЭ и взаимосвязь ГРН с положительными результатами СЭ.

Результаты

Результаты. Распространенность ГРН составила 36,3% (70 пациентов). Пациенты с ГРН чаще имели низкую толерантность к физической нагрузке (р=0,013); скорость кровотока в коронарной артерии в покое и на нагрузке, величина СР были выше у пациентов с ГРН (р=0,009, р=0,008 и р=0,002). Среди пациентов с ГРН снижение СР встречалось реже, чем среди пациентов с адекватной реакцией АД: 45 (64,3%) против 99 (80,5%) (р=0,013).

Заключение

Заключение. Чрезмерное повышение АД во время СЭ может быть ограничивающим признаком, приводящим к преждевременному прерыванию тестирования, что означает худшую переносимость физической нагрузки по сравнению с нормотензивными пациентами. Имеется взаимосвязь между реакцией АД на нагрузку и результатами ABCDE-СЭ, в частности влияние пикового АД на СР. Взаимосвязь между реакцией АД на нагрузку и шагами СЭ, а также ее прогностическая значимость требуют дальнейшего изучения.

Objective

Objective. To assess the incidence of hypertensive response of arterial pressure (BP) to exercise (HRE) during stress echocardiography (SE) in patients with known or suspected coronary artery disease and the effect of HRE on the results of ABCDE-SE.

Materials and methods

Materials and methods. The single-center study included 193 patients who underwent ABCDE-SE (evaluation of wall motion abnormalities, B-lines, contractile reserve (CR), coronary, chronotropic) with traditional assessment of BP response. The incidence of HRE during SE and the relationship of HRe with positive SE results were studied.

Results

Results. The prevalence of HRE was 36.3% (70 patients). Patients with HRE more often had low exercise tolerance (p=0.013); coronary artery blood flow velocity at rest and under load, CR value were higher in patients with HRE (p=0.009, p=0.008 and p=0.002). Among patients with HRE CR decrease was less common than among patients with adequate BP response: 45 (64.3%) versus 99 (80.5%) (p=0.013).

Conclusion

Conclusion. Excessive BP increase during SE may be a limiting feature leading to premature termination of testing, which means worse exercise tolerance compared to normotensive patients. There is a relationship between BP response to load and ABCDE-SE results, in particular the effect of peak BP on CR. The relationship between BP response to load and SE steps, as well as its prognostic significance, require further study.

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The authors declare that there are no conflicts of interest present.