medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2025-22-70-73medalphabet-4612Research ArticleСтатьиМетодические аспекты информативности некоммутабельных лабораторных исследований биологических аналитов при судебно-биологической экспертизеMethodological aspects of the informativeness of non‑commutable laboratory studies of biological analytes in the course of forensic biological examinationhttps://orcid.org/0000-0002-2214-895XСидоровВ. Л.SidorovV. L.

Сидоров Владимир Леонидович, к. б. н., судебный эксперт судебно-биологического отделения; научный сотрудник научно-практического центра испытаний медицинских изделий

Санкт-Петербург

Sidorov Vladimir L., PhD Bio, forensic expert of the Forensic Biology Dept; research fellow at Scientific and Practical Center for Testing Medical Devices

St. Petersburg

v.l.sidorov60@gmail.comhttps://orcid.org/0000-0002-0200-8474ЯгмуровО. Д.YagmurovO. D.

Ягмуров Оразмурад Джумаевич, д. м. н., профессор, начальник

Санкт-Петербург

Yagmurov Orazmurad D., Dr Bio Sci (habil.), professor, head

St. Petersburg

oraz.yagmurov@gmail.comhttps://orcid.org/0000-0003-4656-1025МомыналиевК. Т.MomynalievK. T.

Момыналиев Куват Темиргалиевич, д. б. н., доцент, руководитель Научно-практического центра испытаний медицинских изделий

Москва

Momynaliev Kuvat T., Dr Bio Sci (habil.), associate professor, head of Scientific and Practical Center for Testing Medical Devices

Moscow

KMomynaliev@vniiimt.ruhttps://orcid.org/0009-0005-9994-0522БируляИ. В.BirulyaI. V.

Бируля Ирина Вацлавовна, к. м. н., доцент кафедры клинической лабораторной диагностики с курсом молекулярной медицины

Санкт-Петербург

Birulya Irina V., PhD Med, associate professor at Dept of Clinical Laboratory Diagnostics with a Course in Molecular Medicine

St. Petersburg

irina_bir@bk.ruСПб ГБУЗ «Бюро судебно-медицинской экспертизы»; ФГБУ «Всероссийский научно-исследовательский и испытательный институт медицинской техники» Федеральной службы по надзору в сфере здравоохраненияРоссияSt. Petersburg State Budgetary Healthcare Institution Bureau of Forensic Medical Examination; All-Russian Scientific Research and Testing Institute of Medical Technology of the Federal Service for Healthcare SupervisionRussian FederationСПб ГБУЗ «Бюро судебно-медицинской экспертизы»РоссияSt. Petersburg State Budgetary Healthcare Institution Bureau of Forensic Medical ExaminationRussian FederationФГБУ «Всероссийский научно-исследовательский и испытательный институт медицинской техники» Федеральной службы по надзору в сфере здравоохраненияРоссияAll-Russian Scientific Research and Testing Institute of Medical Technology of the Federal Service for Healthcare SupervisionRussian FederationФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова» Мнздрава РоссииРоссияAcademician I. P. Pavlov First St. Petersburg State Medical UniversityRussian Federation202525102025022«Современная лаборатория» (2)7073Copyright © Сидоров В.Л., Ягмуров О.Д., Момыналиев К.Т., Бируля И.В., 20252025Сидоров В.Л., Ягмуров О.Д., Момыналиев К.Т., Бируля И.В.Sidorov V.L., Yagmurov O.D., Momynaliev K.T., Birulya I.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/4612

В статье представлены результаты методических решений для объективизации критериев достоверности лабораторных исследований биологических материалов, выделенных из «вещественных доказательств» при судебно-биологической экспертизе, т. е. не коммутабельных для традиционных лабораторных технологий. Исследование выполнено на примере динамики содержания общего простатического специфического антигена спермы волонтеров в лабораторной модели, где в качестве тканевой основы «вещественных доказательств» использована марля, а концентрация ПСА определялась методом ИФА. Критерии достоверности результатов лабораторных исследований базируются на принципах внутрилабораторного контроля качества.

The article presents the results of methodological decisions for objectifying criteria for the reliability of laboratory studies of biological materials isolated from “material evidence” during forensic biological examination, i. e. not commutable for traditional laboratory technologies. The study was performed using the example of the dynamics of the content of total prostate-specific antigen in volunteers’ sperm in a laboratory model, where gauze was used as the tissue basis of “material evidence”, and the concentration of total PSA was determined by ELISA. The criteria for the reliability of laboratory test results are based on the principles of in-laboratory quality control.

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The authors declare that there are no conflicts of interest present.