medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2025-15-61-66medalphabet-4477Research ArticleСтатьиВзаимосвязь между стойкой обонятельной дисфункцией, ассоциированной с COVID-19 и морфологией обонятельной луковицыThe relationship between persistent olfactory dysfunction associated with COVID-19 and olfactory bulb morphologyhttps://orcid.org/0009-0003-5880-7704АдамоваА. C.AdamovaA. S.

Адамова Анастасия Сергеевна, аспирант IV года обучения на кафедре неврологии имени академика С. Н. Давиденкова

Adamova Anastasiya S., 4th year post-graduate student at Dept of Neurology n.a. S. N. Davidenkov

https://orcid.org/0000-0001-6814-0454КлочеваЕ. Г.KlochevaE. G.

Клочева Елена Георгиевна, д.м.н., проф. кафедры неврологии имени академика С. Н. Давиденкова

Klocheva Elena G., DM Sci (habil.), professor at Dept of Neurology n.a. S. N. Davidenkov

https://orcid.org/0000-0001-9245-8067ГолдобинВ. В.GoldobinV. V.

Голдобин Виталий Витальевич, д.м.н., зав. кафедрой неврологии имени академика С. Н. Давиденкова

 

Goldobin Vitalii V., DM Sci (habil.), head of Dept of Neurology n.a. S. N. Davidenkov

ФГБОУ ВО «Северо-Западный государственный медицинский университет имени И. И. Мечникова» Минздрава РоссииРоссияNorth-Western State Medical University named after I. I. MechnikovRussian Federation202526072025015«Неврология и психиатрия» (2)6166Copyright © Адамова А.C., Клочева Е.Г., Голдобин В.В., 20252025Адамова А.C., Клочева Е.Г., Голдобин В.В.Adamova A.S., Klocheva E.G., Goldobin V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/4477

Обонятельные нарушения в эпоху пандемии новой коронавирусной инфекции (COVID-19) актуальны как никогда. Согласно статическим данным, около 60% пациентов предъявляют жалобы на обонятельную дисфункцию (ОД) в острый период, но после выздоровления от COVID-19 сохраняется стойкая обонятельная дисфункция более 1 месяца у 6,2 % пациентов. Однако за медицинской помощью обращаются не более 5 % со стойкой ОД. В настоящее время диагностика ОД затруднена ввиду отсутствия единого протокола обследования. Основываясь на изменении объема обонятельной луковицы (ОЛ), предприняты попытки сопоставления данных МРТ обонятельного нерва и выраженности ОД,, в то же время не стоит забывать, что помимо объема ОЛ важна оценка морфологических изменений ОЛ, возникающих в ответ на прямое респираторное воздействие. В статье приводится актуальная информация, включающая оценку 15 метаанализов, посвященных особенностям МРТ-диагностики ОД, ассоциированной с COVID-19, а также результаты личного опыта авторов.

Olfactory disorders are more relevant than ever in the era of the pandemic of the new coronavirus infection (COVID-19). According to statistical data, about 60 % of patients complain of olfactory dysfunction (OD) in the acute period, while 6.2 % of patients note that complaints persist for more than a month after recovery from COVID-19. However, no more than 5 % of those with persistent OD seek medical help. Currently, the diagnosis of OD is difficult due to the lack of a single examination protocol. Attempts have been made to compare the MRI data of the olfactory nerve and the severity of OD, based on changes in the volume of the olfactory bulb (OB), at the same time, one should not forget that in addition to the volume of OB, it is possible to assess the morphology of OB, which changes in response to direct respiratory exposure. The article provides up-to-date information, including an assessment of 15 meta-analyses on the features of MRI diagnosis of OD associated with COVID-19, as well as the results of the authors' personal experience.

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The authors declare that there are no conflicts of interest present.