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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-15-7-13</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4444</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Профилактическое лечение мигрени: практические рекомендации Международного общества головной боли (IHS)</article-title><trans-title-group xml:lang="en"><trans-title>Preventive Pharmacological Treatment of Migraine: International Headache Society (IHS) Global Practice Recommendations</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9978-4180</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филатова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Filatova</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филатова Елена Глебовна, д.м.н., проф., проф. кафедры нервных болезней ИПО; врач-невролог</p><p>Москва</p></bio><bio xml:lang="en"><p>Filatova Elena G., DM Sci (habil.), professor at Dept of Neurology, Institute of Professional Education; neurologist</p><p>Moscow </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9828-2509</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амелин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Amelin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Амелин Александр Витальевич, д.м.н., проф., проф. кафедры неврологии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Amelin Alexander V., DM Sci (habil.), professor at Dept of Neurology</p><p>St. Petersburg </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9600-5540</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Латышева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Latysheva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Латышева Нина Владимировна, д.м.н., доцент, проф. кафедры нервных болезней ИПО; врач-невролог</p><p>Москва</p></bio><bio xml:lang="en"><p>Latysheva Nina V., DM Sci (habil.), professor at Dept of Neurology, Institute of Professional Education; neurologist</p><p>Moscow </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет имени И. М. Сеченова» Минздрава России (Сеченовский университет); Клиника головной боли и вегетативных расстройств им. академика Александра Вейна</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I. M. Sechenov First Moscow State Medical University (Sechenov University); Alexander Vein Headache Clinic</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First State Medical University of St. Petersburg (Pavlov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>26</day><month>07</month><year>2025</year></pub-date><volume>0</volume><issue>15</issue><issue-title>«Неврология и психиатрия» (2)</issue-title><fpage>7</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Филатова Е.Г., Амелин А.В., Латышева Н.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Филатова Е.Г., Амелин А.В., Латышева Н.В.</copyright-holder><copyright-holder xml:lang="en">Filatova E.G., Amelin A.V., Latysheva N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4444">https://www.med-alphabet.com/jour/article/view/4444</self-uri><abstract><p>В статье представлен адаптированный перевод практических рекомендаций по профилактическому лечению мигрени, выпущенных в конце 2024 г. Международным обществом головной боли (IHS). Документ содержит 16 наиболее важных практических вопросов по профилактике мигрени, ответы на которые получены из клинических рекомендаций разных стран, метаанализов и рандомизированных клинических исследований (РКИ).</p><p>Основной целью практических рекомендаций по профилактике мигрени является оптимизация использования лекарственных средств для эффективного контроля за часто возникающей и хронической мигренью и повышения качества медицинской помощи у наибольшего числа пациентов в странах с различным экономическим уровнем развития. В Российской Федерации (РФ) доступны таргетные профилактические препараты (анти-CGRP моноклональные антитела, гепанты) и ботулотоксин типа А, а также большинство классических таблетированных средств. Таким образом, в нашей стране возможно осуществлять профилактическое лечение мигрени любого, в том числе оптимального уровня. В комментариях этой статьи авторы российской версии стремились адаптировать ответы на наиболее важные вопросы к клинической практике в РФ.</p></abstract><trans-abstract xml:lang="en"><p>The article presents an adapted translation of the practice recommendations for the preventive treatment of migraine, released in late 2024 by the International Headache Society (IHS). The document contains 16 of the most important practical questions on migraine prevention, the answers to which are obtained from clinical guidelines from different countries, meta-analyses and randomized clinical trials (RCTs).The main objective of these practice recommendations for migraine prevention is to optimize the use of drugs for effective control of frequent and chronic migraine and to improve the quality of medical care for the greatest number of patients in countries with different levels of economic development. In the Russian Federation (RF), both targeted prophylactic drugs (anti-CGRP monoclonal antibodies, gepants), botulinum toxin type A and most classical oral medications are available. Thus, in our country it is possible to offer preventive treatment of migraine of any level, including the optimal one. In the comments to this article, the authors of the Russian version sought to adapt the answers to the most important questions to clinical practice in the Russian Federation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мигрень</kwd><kwd>лечение мигрени</kwd><kwd>профилактика мигрени</kwd><kwd>рекомендации по профилактике мигрени</kwd></kwd-group><kwd-group xml:lang="en"><kwd>migraine</kwd><kwd>migraine treatment</kwd><kwd>migraine prevention</kwd><kwd>migraine prevention guidelines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Puledda F, Sacco S, Diener HC, Ashina M, Al-Khazali HM, Ashina S, Burstein R, Liebler E, Cipriani A, Chu MK, Cocores A, Dodd-Glover F, Ekizoğlu E, Garcia-Azorin D, Göbel CH, Goicochea MT, Hassan A, Hirata K, Hoffmann J, Jenkins B, Kamm K, Lee MJ, Ling YH, Lisicki M, Martinelli D, Monteith TS, Ornello R, Özge A, Peres MFP, Pozo-Rosich P, Romanenko V, Schwedt TJ, Souza MNP, Takizawa T, Terwindt GM, Thuraiaiyah J, Togha M, Vandenbussche N, Wang SJ, Yu S, Tassorelli C. 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