medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2025-9-42-46medalphabet-4385Research ArticleСтатьиСиндром Когана как междисциплинарная проблема (обзор литературы)Cogan’s syndrome as an interdisciplinary problem (literature review)https://orcid.org/0009-0006-7244-3507ДудовТ. Р.DudovT. R.

Дудов Темирлан Русланович - ассистент кафедры госпитальной терапии.

Ставрополь

Temirlan R. Dudov - assistant ast Dept of Hospital Therapy.

Stavropol

timur222123@mail.ruhttps://orcid.org/0000-0001-6392-8461КоройП. В.KoroyP. V.

Корой Павел Владимирович - д.м.н., проф., проф. кафедры госпитальной терапии.

Ставрополь

Pavel V. Koroy - DM Sci (habil.), professor, professor at Dept of Hospital Therapy.

Stavropol

paule75@yandex.ruhttps://orcid.org/0000-0003-4510-3604ГладкихН. Н.GladkikhN. N.

Гладких Наталья Николаевна - д.м.н., проф., проф. кафедры госпитальной терапии.

Ставрополь

Natalia N. Gladkikh - DM Sci (habil.), professor at Dept of Hospital Therapy.

Stavropol

ngladkih@mail.ruhttps://orcid.org/0000-0002-5727-1640ЯгодаА. В.YagodaA. V.

Ягода Александр Валентинович - д.м.н., проф., зав. кафедрой госпитальной терапии.

Ставрополь

Alexander V. Yagoda - DM Sci (habil.), professor, head of Dept of Hospital Therapy.

Stavropol

alexander.yagoda@gmail.comhttps://orcid.org/0009-0004-4747-2715КозаковаС. А.KozakovaS. A.

Козакова Светлана Александровна - к.м.н., доцент кафедры госпитальной терапии.

Ставрополь

Svetlana A. Kozakova - PhD Med, associate professor at Dept of Hospital Therapy.

Stavropol

kozakova.76@mail.ruФГБОУ ВО «Ставропольский государственный медицинский университет» Минздрава РоссииРоссияStavropol State Medical UniversityRussian Federation20250606202509Ревматология в общей врачебной практике (1)4246Copyright © Дудов Т.Р., Корой П.В., Гладких Н.Н., Ягода А.В., Козакова С.А., 20252025Дудов Т.Р., Корой П.В., Гладких Н.Н., Ягода А.В., Козакова С.А.Dudov T.R., Koroy P.V., Gladkikh N.N., Yagoda A.V., Kozakova S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/4385

Синдром Когана – системный васкулит, принадлежащий к группе вариабельных васкулитов. Он характеризуется поражением глаз (интерстициальный кератит) и аудиовестибулярной системы (нейросенсорная тугоухость, вестибулярные нарушения), реже – развитием системных проявлений (аортит, неврологическая патология). Системное поражение с вовлечением глаз и аудиовестибулярного аппарата требует дифференциальной диагностики с широким спектром болезней, в том числе гранулематозома Вегенера. В обзоре подробно освещены данные об этиопатогенезе, клинической картине, диагностике, принципах терапии и прогнозе этого редкого заболевания. Сложность диагностики и лечения синдрома Когана подчеркивает необходимость междисциплинарного подхода к ведению таких пациентов.

Cogan’s syndrome is a systemic vasculitis belonging to the group of variable vasculitis. It is characterized by damage to the eyes (interstitial keratitis) and the audiovisual system (sensorineural hearing loss, vestibular disorders), less often by the development of systemic manifestations (aortitis, neurological disorders). Systemic damage involving the eyes and audiovestibular apparatus requires differential diagnosis of a wide range of diseases, including Wegener's granulomatosis. The review provides detailed information on the etiopathogenesis, clinical picture, diagnosis, principles of therapy, and prognosis of this rare disease. The complexity of the diagnosis and treatment of Cogan’s syndrome highlights the need for an interdisciplinary approach to the management of such patients.

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The authors declare that there are no conflicts of interest present.