medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2025-8-40-44medalphabet-4355Research ArticleСтатьиЭффективность и безопасность ингибиторов янускиназ в лечении гнездной алопеции у детейEfficacy and safety of janus kinase inhibitors in the treatment of alopecia areata in childrenhttps://orcid.org/0000-0003-2252-8570МурашкинН. Н.MurashkinN. N.

Мурашкин Николай Николаевич, д.м.н., профессор, руководитель НИИ детской дерматологии

Москва

Murashkin Nikolay N., DM Sci (habil.), professor, head of Pediatric Dermatology Research Institute

Moscow

https://orcid.org/0009-0008-1649-593XГориславскаяТ.  А.GorislavskaiaT.  A.

Гориславская Татьяна Алексеевна, младший научный сотрудник лаборатории патологии кожи у детей, отдел научных исследований в педиатрии

Москва

Gorislavskaia Tatiana A., junior researcher at Laboratory of Pediatric Skin Pathology at Dept of Pediatric Research

Moscow

tatiana.gorislavskaia@gmail.comФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава РоссииРоссияNational Medical Research Center for Children’s HealthRussian Federation20250406202508Дерматология (1)4044Copyright © Мурашкин Н.Н., Гориславская Т.А., 20252025Мурашкин Н.Н., Гориславская Т.А.Murashkin N.N., Gorislavskaia T.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/4355

Гнездная алопеция – аутоиммунное воспалительное заболевание, характеризующееся нерубцовым выпадением волос. Представленный обзор систематизирует современные данные о патогенезе заболевания и эффективности системной терапии JAK-ингибиторами в педиатрической практике. Особое внимание уделено селективным препаратам и их безопасности у детей с тяжёлыми формами гнездной алопеции.

Alopecia areata is an autoimmune inflammatory disease characterized by non-scarring hair loss. This review summarizes current data on disease pathogenesis and systemic JAK inhibitor therapy in pediatric patients. Special attention is given to selective agents and their safety in children with severe alopecia areata.

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The authors declare that there are no conflicts of interest present.