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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-821-25</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4350</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Возможности применения липофилинга в терапии склероатрофического лихена вульвы</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of lipofilling in the therapy of vulvar lichen sclerosus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1566-5964</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Порсохонова</surname><given-names>Д. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Porsokhonova</surname><given-names>D. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Порсохонова Дэля Фозиловна, д.м.н., старший научный сотрудник, зав. научной лабораторией по изучению проблем ИППП и Репродуктивных нарушений</p><p>Ташкент</p></bio><bio xml:lang="en"><p>Porsokhonova Delya F., DM Sci (habil.), senior researcher, head of the Scientific Laboratory for the Study of STIs and Reproductive</p><p>Tashkent</p></bio><email xlink:type="simple">delya.porsokhonova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0171-9215</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якубович</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakubovich</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якубович Андрей Игоревич, д.м.н., профессор, зав. кафедрой дерматовенерологии и косметологии</p><p>Иркутск</p></bio><bio xml:lang="en"><p>Yakubovich Andrey I., DM Sci (habil.), professor, head of Dept of Dermatovenereology and Cosmetology</p><p>Irkutsk</p></bio><email xlink:type="simple">divanand@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7245-3506</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Садыков</surname><given-names>Р. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Sadikov</surname><given-names>R. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Садыков Расул Рустамович, доктор медицинских наук, старший научный сотрудник, ассистент кафедры хирургических болезней</p><p>Ташкент</p></bio><bio xml:lang="en"><p>Sadykov Rasul R., DM Sci (habil.), senior researcher, assistant professor at Dept of Surgical Diseases</p><p>Tashkent</p></bio><email xlink:type="simple">Rrsadykov84@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-6283-5633</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Илесова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilesova</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Илесова Нуржанар Нургалиевна, базовый докторант</p><p>Ташкент</p></bio><bio xml:lang="en"><p>Ilesova Nurjanar N., basic doctoral student</p><p>Tashkent</p></bio><email xlink:type="simple">nur_janar95@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>«Республиканский специализированный научно-практический медицинский центр дерматологии и косметологии» Минздрава Республики Узбекистан</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Republican Specialized Scientific and Practical Medical Center of Dermatology and Cosmetology</institution><country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Иркутский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Ташкентская Медицинская Академия</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Tashkent Medical Academy</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2025</year></pub-date><volume>0</volume><issue>8</issue><issue-title>Дерматология (1)</issue-title><fpage>21</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Порсохонова Д.Ф., Якубович А.И., Садыков Р.Р., Илесова Н.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Порсохонова Д.Ф., Якубович А.И., Садыков Р.Р., Илесова Н.Н.</copyright-holder><copyright-holder xml:lang="en">Porsokhonova D.F., Yakubovich A.I., Sadikov R.R., Ilesova N.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4350">https://www.med-alphabet.com/jour/article/view/4350</self-uri><abstract><p>Статья представляет применение липофилинга, как инновационного метода лечения склероатрофического лихена вульвы (САЛВ). Основные методы лечения САЛВ нередко сопровождаются побочными эффектами, рецидивами или ограниченной эффективностью при прогрессировании заболевания. В этом контексте липофилинг, основанный на трансплантации аутологичной жировой ткани, привлекает внимание как перспективный малоинвазивный терапевтический подход. Результаты проведенного клинического исследования подтверждают эффективность аутолипофилинга при лечении САЛВ. Полученные результаты исследований показали, что аутолипофилинг представляет собой перспективный метод лечения склероатрофического лихена вульвы, который не только эффективно устраняет симптомы, но и восстанавливает структуру тканей, улучшая их эластичность и внешний вид. Однако для стандартизации терапевтических подходов, подтверждения эффективности метода и долгосрочной безопасности необходимо проведение дополнительных исследований.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the application of lipofilling as an innovative method of treating of the vulvar lichen sclerosus (VLS). The main methods of treating VLS are often accompanied by side effects, relapses, or limited effectiveness in the progression of the disease. In this context, lipofilling based on autologous adipose tissue transplantation attracts attention as a promising minimally invasive therapeutic approach. The results of the conducted clinical study confirm the effectiveness of autolipophilling in the treatment of VLS. The obtained research results showed that autolipophilling is a promising method of treating of the vulvar lichen sclerosus, which not only effectively eliminates the symptoms, but also restores the structure of tissues, improving their elasticity and appearance. However, additional research is needed to standardize therapeutic approaches, confirm the effectiveness of the method, and ensure long-term safety.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>склероатрофический лихен вульвы</kwd><kwd>лечение</kwd><kwd>липофилинг</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vulvar lichen sclerosus</kwd><kwd>treatment</kwd><kwd>lipofilling</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бабаян А.М., Калинина Н.И. Патоморфология склероатрофического лихена: современные подходы. 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