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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-6-13-20</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4337</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Особенности микробиоты кишечника при заболеваниях желчевыводящих путей</article-title><trans-title-group xml:lang="en"><trans-title>Features of gut microbiota in diseases of the biliary tract</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7083-2692</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котляров</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotlyarov</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котляров Станислав Николаевич, д. м. н., доцент, заведующий кафедрой сестринского дела,</p><p>г. Рязань.</p></bio><bio xml:lang="en"><p>Kotlyarov Stanislav N., DM Sci (habil.), Associate Professor, Head of Nursing Dept.,</p><p>Ryazan.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5872-1308</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шелухина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheloukhina</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шелухина Светлана Витальевна, к. м. н., ассистент кафедры сестринского дела,</p><p>г. Рязань.</p></bio><bio xml:lang="en"><p>Sheloukhina Svetlana V., PhD Med, Assistant Professor at Nursing Dept.,</p><p>Ryazan.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6753-7828</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Markova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маркова Елена Владимировна, к. м. н., ассистент кафедры сестринского дела,</p><p>г. Рязань.</p></bio><bio xml:lang="en"><p>Markova Elena V., PhD Med, Assistant Professor at Nursing Dept.,</p><p>Ryazan.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3402-1128</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бутов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Butov</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бутов Михаил Александрович, д. м. н., профессор, профессор кафедры сестринского дела, заслуженный врач Российской Федерации,</p><p>г. Рязань.</p></bio><bio xml:lang="en"><p>Butov Mikhail A., DM Sci (habil.), Professor, Professor at Nursing Dept, Honored Doctor of the Russian Federation,</p><p>Ryazan.</p></bio><email xlink:type="simple">butov-m@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4396-5051</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Василевская</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilevskaya</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Василевская Анна Станиславовна, к. м. н., доцент кафедры сестринского дела,</p><p>г. Рязань.</p></bio><bio xml:lang="en"><p>Vasilevskaya Anna S., PhD Med, Associate Professor at Nursing Dept.,</p><p>Ryazan.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Рязанский государственный медицинский университет имени академика И. П. Павлова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ryazan State Medical University named after academician I. P. Pavlov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>26</day><month>05</month><year>2025</year></pub-date><volume>0</volume><issue>6</issue><issue-title>«Гастроэнтерология и диетология» (1)</issue-title><fpage>13</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Котляров С.Н., Шелухина С.В., Маркова Е.В., Бутов М.А., Василевская А.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Котляров С.Н., Шелухина С.В., Маркова Е.В., Бутов М.А., Василевская А.С.</copyright-holder><copyright-holder xml:lang="en">Kotlyarov S.N., Sheloukhina S.V., Markova E.V., Butov M.A., Vasilevskaya A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4337">https://www.med-alphabet.com/jour/article/view/4337</self-uri><abstract><p>Цель исследования. Состав, метаболическая и иммунная активность микробиоты кишечника важны для нормального функционирования не только кишечника, но и других органов и систем.Материалы и методы. В настоящем обзоре проанализированы литературные данные о взаимосвязи микробиоты кишечника при заболеваниях желчевыводящих путей.Результаты и заключение. Изменения микробиоты кишечника могут вызывать не только изменения в системе органов пищеварения, но и влиять на состояние организма в целом.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of the study. The composition, metabolic and immune activity of the gut microbiota are important for the normal functioning not only of the intestine, but also of other organs and systems.Materials and methods. The present review analysed the literature data on the relationship of gut microbiota in biliary tract diseases.Results and conclusion. Changes in gut microbiota can cause not only changes in the system of digestive organs, but also affect the state of the organism as a whole.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>микробиота кишечника</kwd><kwd>заболевания желчевыводящих путей</kwd><kwd>иммунная система</kwd><kwd>метаболизм</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gut microbiota</kwd><kwd>biliary tract diseases</kwd><kwd>immune system</kwd><kwd>metabolism</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou B, Yuan Y, Zhang S, Guo C, Li X, Li G, et al. Intestinal Flora and Disease Mutually Shape the Regional Immune System in the Intestinal Tract. Front Immunol. 2020; 11: 575.</mixed-citation><mixed-citation xml:lang="en">Zhou B, Yuan Y, Zhang S, Guo C, Li X, Li G, et al. Intestinal Flora and Disease Mutually Shape the Regional Immune System in the Intestinal Tract. 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