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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-1-97-104</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4205</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Безболезненное формирование эстетического рубца слизистой оболочки рта методикой лазерной пайки ран в эксперименте</article-title><trans-title-group xml:lang="en"><trans-title>Painless formation of an aesthetic scar on the oral mucosa using laser wound soldering: an experimental study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-7968-8524</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сорокина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sorokina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сорокина Елена Александровна, ассистент кафедры детской, профилактической стоматологии и ортодонтии</p><p>Москва</p></bio><bio xml:lang="en"><p>Sorokina Elena A., Associate Professor of Department of Pediatric, Preventive Dentistry and Orthodontics</p><p>Moscow</p></bio><email xlink:type="simple">sorokina_e_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5312-9516</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозова Елена Анатольевна, д.м.н., доцент, проф. кафедры пропедевтики стоматологических заболеваний</p><p>Москва</p></bio><bio xml:lang="en"><p>Morozova Elena A., DM Sci, Professor of the Department of Propaedeutics of Dental diseases</p><p>Zelenograd</p></bio><email xlink:type="simple">morozova_elan@pfur.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6514-2411</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасименко</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimenko</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Герасименко Александр Юрьевич, д.т.н., доцент, профессор, зав. лаб.</p><p> г. Зеленоград</p></bio><bio xml:lang="en"><p>Gerasimenko Alexander Yu., DM, Professor at the Institute of Biomedical Systems, Head of the laboratory</p><p>Moscow</p></bio><email xlink:type="simple">gerasimenko@bms.zone</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8595-8864</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасенко</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasenko</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарасенко Светлана Викторовна, д.м.н., проф., зав. кафедрой хирургической стоматологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Tarasenko Svetlana V., M.D., PhD., Professor, Chief of Department of Surgical Dentistry</p><p>Moscow</p></bio><email xlink:type="simple">tarasenko_s_v@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ВО «Первый МГМУ им. И.М. Сеченова» МЗ Р</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ ВО «Первый МГМУ им. И.М. Сеченова» МЗ РФ; Национальный исследовательский университет «МИЭТ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation; National Research University of Electronic Technology «MIET»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>03</day><month>03</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><issue-title>Стоматология (1)</issue-title><fpage>97</fpage><lpage>104</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сорокина Е.А., Морозова Е.А., Герасименко А.Ю., Тарасенко С.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Сорокина Е.А., Морозова Е.А., Герасименко А.Ю., Тарасенко С.В.</copyright-holder><copyright-holder xml:lang="en">Sorokina E.A., Morozova E.A., Gerasimenko A.Y., Tarasenko S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4205">https://www.med-alphabet.com/jour/article/view/4205</self-uri><abstract><sec><title>Введение</title><p>Введение. Количество хирургических вмешательств в ротовой полости постоянно растет, так как стоматологические заболевания в настоящее время занимают одно из ведущих мест по встречаемости. В связи с чем необходимость выбора техники наложения швов при выполнении операций напрямую связана с качеством оказываемой стоматологической помощи. Одним из перспективных методов является лазерная пайка тканей, обеспечивающая быстрое и герметичное соединение тканей в условиях стерильности раны, сокращаются сроки заживления раны, уменьшается размер рубца.</p></sec><sec><title>Цель</title><p>Цель. Повышение эффективности хирургического лечения стоматологических пациентов путем экспериментальной разработки методики лазерной пайки слизистой оболочки рта с использованием лазерного излучения и биоприпоя.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Экспериментальная модель исследования была создана на 16 лабораторных кроликах породы шиншилла. Линейные раны на слизистой оболочке рта делали скальпелем и ушивали. Всех кроликов разделили на 2 группы исследования: 1) раны ушивали нитью Пролен 5.0; 2) края ран соединяли методикой лазерной пайки тканей с помощью лазерного аппарата с длиной волны 970 нм и биоприпоя на основе бычьего сывороточного альбумина, индоцианина зелёного, одностенных углеродных нанотрубок, коллагена I типа и нити Пролен 5.0. В послеоперационном периоде у лабораторных животных оценивали интенсивность боли, выраженность отека, интенсивность окраски гиперемии в области оперативного вмешательства на 1, 3 и 5 сутки в баллах.</p></sec><sec><title>Результаты</title><p>Результаты. Экспериментальные исследования на животных in vivo показали, что наилучшая регенерация была при соединении краев ран с помощью лазерной пайки тканей с использованием лазерного излучения и биоприпоя, в послеоперационном периоде минимальны боль, отек и не выражена гиперемия, расхождения швов и некроза тканей не наблюдали. В области лазерного шва была более ранняя эпителизация, формирующийся рубец был очень тонкий и едва отличим от окружающих тканей.</p></sec><sec><title>Заключение</title><p>Заключение. Применение лазерного излучения в сочетании с биоприпоем является перспективной методикой для ушивания ран в полости рта, так как происходит безболезненное ускорение послеоперационных регенеративных процессов с минимальными рисками формирования грубого рубца.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The number of surgical interventions in the oral cavity is steadily increasing, as dental diseases are among the most common health conditions today. Consequently, the choice of suturing techniques during surgical procedures is directly linked to the quality of dental care. One promising approach is laser tissue soldering, which enables rapid and airtight tissue bonding under sterile wound conditions, leading to faster healing and reduced scar formation.</p></sec><sec><title>Objective</title><p>Objective. To enhance the effectiveness of surgical treatment in dental patients by experimentally developing a laser tissue soldering technique for the oral mucosa using laser radiation and a biocompatible soldering material.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The experimental study was conducted on 16 chinchilla breed laboratory rabbits. Linear wounds were created on the oral mucosa using a scalpel and then sutured. The animals were divided into two study groups: 1) the wounds were sutured using Prolene 5.0 thread; 2) the wound edges were joined using the laser tissue soldering technique, employing a 970 nm wavelength laser device and a biocompatible solder composed of bovine serum albumin, indocyanine green, single-walled carbon nanotubes, type I collagen, and Prolene 5.0 thread. Postoperative assessments included pain intensity, swelling severity, and the degree of hyperemia coloration at the surgical site on days 1, 3, and 5, using a scoring system.</p></sec><sec><title>Results</title><p>Results. In vivo experimental studies demonstrated that laser tissue soldering with laser radiation and biocompatible solder provided superior wound regeneration. Postoperatively, pain and swelling were minimal, hyperemia was not pronounced, and no cases of suture dehiscence or tissue necrosis were observed. The laser-formed suture site exhibited early epithelialization, and the resulting scar was extremely thin and nearly indistinguishable from the surrounding tissue.</p></sec><sec><title>Conclusion</title><p>Conclusion. The use of laser radiation in combination with biocompatible solder represents a promising technique for wound closure in the oral cavity, as it enables painless acceleration of postoperative regenerative processes with minimal risk of hypertrophic scar formation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хирургическая стоматология</kwd><kwd>полость рта</kwd><kwd>слизистая оболочка рта</kwd><kwd>лазер</kwd><kwd>лазерная медицина</kwd><kwd>биоприпой</kwd><kwd>лазерная пайка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>oral surgery</kwd><kwd>oral cavity</kwd><kwd>oral mucosa</kwd><kwd>laser</kwd><kwd>laser medicine</kwd><kwd>biosolder</kwd><kwd>laser soldering</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Евсеев М.А. Хирургический шов: эволюция нити и иглы. Клинический опыт Двадцатки. 2012: 4 (16):59–62.</mixed-citation><mixed-citation xml:lang="en">Evseev M.A. Surgical suture: the evolution of thread and needle. Clinical experience of the Twenties. 2012; 4 (16):59-62.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Семенов Г.М., Петришин В.Л., Ковшова М.В. Хирургический шов. 3-е изд. Санкт-Петербург: Питер. 2012: 256. ISBN 978-5-496-00023-9.</mixed-citation><mixed-citation xml:lang="en">Semenov G.M., Petrishin V.L., Kovshova M.B. Surgical staining. The 3rd is decreasing. I’ve Been Through St. Petersburg: Peter. 2012: 256. ISBN 978-5-496-00023-9.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Робустова Т.Г. Хирургическая стоматология. 4-е изд. Москва: Медицина. 2010: 622. Robustova T.G. Surgical dentistry. 4th ed. Moscow: Medicine. 2010: 622.</mixed-citation><mixed-citation xml:lang="en">Робустова Т.Г. Хирургическая стоматология. 4-е изд. Москва: Медицина. 2010: 622. Robustova T.G. Surgical dentistry. 4th ed. Moscow: Medicine. 2010: 622.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">La Rosa GRM., Scapellato S., Cicciu M., Pedulla E. Antimicrobial Activity of Antibacterial Sutures in Oral Surgery: A Scoping Review. International Dental Journal. 2024: 6539(24):00052-2. https://doi.org/10.1016/j.identj.2024.01.029</mixed-citation><mixed-citation xml:lang="en">La Rosa GRM., Scapellato S., Cicciu M., Pedulla E. Antimicrobial Activity of Antibacterial Sutures in Oral Surgery: A Scoping Review. International Dental Journal. 2024: 6539(24):00052-2. https://doi.org/10.1016/j.identj.2024.01.029</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Faris A., Khalid L., Hashim M., Yaghi S., Magde T., Bouresly W., Hamdoon Z., Uthman AT., Marei H., Al-Rawi N. Characteristics of Suture Materials Used in Oral Surgery: Systematic Review. Int Dent J. 2022:72(3):278-287. https://doi.org/10.1016/j.identj.2022.02.005.</mixed-citation><mixed-citation xml:lang="en">Faris A., Khalid L., Hashim M., Yaghi S., Magde T., Bouresly W., Hamdoon Z., Uthman AT., Marei H., Al-Rawi N. Characteristics of Suture Materials Used in Oral Surgery: Systematic Review. Int Dent J. 2022:72(3):278-287. https://doi.org/10.1016/j.identj.2022.02.005.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Рябкин Д.И., Сучкова В.В., Герасименко А.Ю. Предсказание прочности на разрыв лазерных сварных швов биотканей методами машинного обучения. Медицинская техника. 2023:2(338):26–29.</mixed-citation><mixed-citation xml:lang="en">Ryabkin D.I., Suchkova V.V., Gerasimenko A.Yu. Prediction of tensile strength of laser welds of biological fabrics by machine learning methods. Medical equipment. 2023:2(338):26–29.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Peterson AW., Halter M., Tona A., Plant AL. High resolution surface plasmon resonance imaging of single cells. BMC Cell Biology. 2014:15(35):2–14. doi:10.1186/1471-2121-15-35. PMC 4289309. PMID 25441447.</mixed-citation><mixed-citation xml:lang="en">Peterson AW., Halter M., Tona A., Plant AL. High resolution surface plasmon resonance imaging of single cells. BMC Cell Biology. 2014:15(35):2–14. doi:10.1186/1471-2121-15-35. PMC 4289309. PMID 25441447.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Македонова Ю.А., Афанасьева О.Ю., Александров А.В., Кабытова М.В., Чаплиева Е.М. Возможности применения медицинского геля при пластике перфорации верхнечелюстной пазухи. Cathedra-Кафедра. Стоматологическое образование. 2023:(85):62–65.</mixed-citation><mixed-citation xml:lang="en">Makedonova Yu.A., Afanasyeva O.Yu., Alexandrov A.V., Kabytova M.V., Chaplieva E.M. The possibilities of using medical gel for plastic perforation of the maxillary sinus. Cathedral-Department. Dental education. 2023:(85):62–65.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Сигал З.М., Бабушкин Ф.Г., Никифорова А.Н., Капустин Б.Б. Хирургические швы. Учебное пособие. Ижевск. 2009:136.</mixed-citation><mixed-citation xml:lang="en">Sigal Z.M., Babushkin F.G., Nikiforova A.N., Kapustin B.B. Surgical sutures. The training manual. Izhevsk. 2009:136.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Акопов А.Л., Артюх Д.Ю., Молнар Т.Ф. История механического скобочного хирургического шва (обзор литературы). Вестник хирургии им. И.И. Грекова. 2020:179(6):81–88.</mixed-citation><mixed-citation xml:lang="en">Akopov A.L., Artyukh D.Yu., Molnar T.F. History of mechanical brace surgical suture (literature review). Bulletin of Surgery named after I.I. Grekov. 2020:179(6):81–88.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Глиник А.А., Авлас С.Д., Стебунов С.С., Руммо О.О., Германович В.И. Бариатрические операции при морбидном ожирении. Новости хирургии. 2021:29(6):662–670.</mixed-citation><mixed-citation xml:lang="en">Glinnik A.A., Avlas S.D., Stebunov S.S., Rummo O.O., Germanovich V.I. Bariatric surgery in morbid obesity. Surgery news. 2021:29(6):662–670.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ашурко И.П., Крылова Д.А., Белкин В.О., Яценко А.Г., Тарасенко С.В. Результаты применения коллагенового матрикса при менеджменте мягких тканей в области дентальных имплантатов во фронтальном отделе верхней челюсти. Проблемы стоматологии. 2023:19(4):69–76.</mixed-citation><mixed-citation xml:lang="en">Ashurkov I.P., Krylova D.A., Belkin V.O., Yatsenko A.G., Tarasenko S.V. Results of the use of collagen matrix in soft tissue management in the ﬁeld of dental implants in the frontal maxilla. Problems of dentistry. 2023:19(4):69–76.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Sudarsan P.K.S., Lata J., Kajla P., Sooch S.P.S., Prashar S. Comparative study between the efﬁcacy of conventional plain vicryl and antibacterial vicryl containing triclosan. International Journal of Advanced Research. 2023:11(07):241–250. https://dx.doi.org/10.21474/IJAR01/17225.</mixed-citation><mixed-citation xml:lang="en">Sudarsan P.K.S., Lata J., Kajla P., Sooch S.P.S., Prashar S. Comparative study between the efﬁcacy of conventional plain vicryl and antibacterial vicryl containing triclosan. International Journal of Advanced Research. 2023:11(07):241–250. https://dx.doi.org/10.21474/IJAR01/17225.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kim H., Hwang K., Yun S. Catgut and its Use in Plastic Surgery. Journal of craniofacial surgery. 2020:31(3): 876-878. https://doi.org/10.1097/SCS.0000000000006149.</mixed-citation><mixed-citation xml:lang="en">Kim H., Hwang K., Yun S. Catgut and its Use in Plastic Surgery. Journal of craniofacial surgery. 2020:31(3): 876-878. https://doi.org/10.1097/SCS.0000000000006149.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Parmar G.S., Ghodke B., Meena A.K. Releasable Suture versus Autologous Blood for Pterygium Surgery using Conjunctival Autografts. J Ophthalmic Vis Res. 2020:15(1):32-37. https://doi.org/10.18502/jovr.v15i1.5938.</mixed-citation><mixed-citation xml:lang="en">Parmar G.S., Ghodke B., Meena A.K. Releasable Suture versus Autologous Blood for Pterygium Surgery using Conjunctival Autografts. J Ophthalmic Vis Res. 2020:15(1):32-37. https://doi.org/10.18502/jovr.v15i1.5938.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Muth D.R., Wolf A., Kreutzer T., Shajari M., Vounotrypidis E., Priglinger S., Mayer W.J. Safety and Efﬁcacy of Current Sclera Fixation Methods for Intraocular Lenses and Literature Overview. Klinische Monatsblatter fur Augenheilkunde. 2021:238(08): 868–874. https://doi.org/10.1055/a-1333-3199.</mixed-citation><mixed-citation xml:lang="en">Muth D.R., Wolf A., Kreutzer T., Shajari M., Vounotrypidis E., Priglinger S., Mayer W.J. Safety and Efﬁcacy of Current Sclera Fixation Methods for Intraocular Lenses and Literature Overview. Klinische Monatsblatter fur Augenheilkunde. 2021:238(08): 868–874. https://doi.org/10.1055/a-1333-3199.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Mohammad S., Hanstein R., Lo Y., Levy I. Validating a Low-Fidelity Model for Microsurgical Anastomosis Training. JBJS Open Access. 16;6(3):e20.00148. https://doi.org/10.2106/JBJS.OA.20.00148.</mixed-citation><mixed-citation xml:lang="en">Mohammad S., Hanstein R., Lo Y., Levy I. Validating a Low-Fidelity Model for Microsurgical Anastomosis Training. JBJS Open Access. 16;6(3):e20.00148. https://doi.org/10.2106/JBJS.OA.20.00148.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Тучин В.В. Лазеры и волоконная оптика в биомедицинских исследованиях. Монография. Москва. Ай Пи Ар Медиа. 2021:495. ISBN 978-5-4497-0568-6.</mixed-citation><mixed-citation xml:lang="en">Tuchin V.V. Biomedical optics ﬁber research and laser technology. А monograph. Moscow. A Man of Very Media Hips. 2021:495. ISBN 978-5-4497-0568-6.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hsu V.M., Aldahan A.S., Tsatalis J.P., Perper M., Nouri K. Efﬁcacy of Nd:YAG laser therapy for the treatment of verrucae: a literature review. Lasers in Medical Science. 2017:32(5):1207–1211. https://doi.org/10.1007/s10103-017-2219-5.</mixed-citation><mixed-citation xml:lang="en">Hsu V.M., Aldahan A.S., Tsatalis J.P., Perper M., Nouri K. Efﬁcacy of Nd:YAG laser therapy for the treatment of verrucae: a literature review. Lasers in Medical Science. 2017:32(5):1207–1211. https://doi.org/10.1007/s10103-017-2219-5.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Nadhreen A.A., Alamoudi N.M., Elkhodary H.M. Low-level laser therapy in dentistry: Extra-oral applications. Nigerian Journal of Clinical Practice. 2019:22(10):1313-1318. https://doi.org/10.4103/njcp.njcp_53_19.</mixed-citation><mixed-citation xml:lang="en">Nadhreen A.A., Alamoudi N.M., Elkhodary H.M. Low-level laser therapy in dentistry: Extra-oral applications. Nigerian Journal of Clinical Practice. 2019:22(10):1313-1318. https://doi.org/10.4103/njcp.njcp_53_19.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Li-Da H., Zhen L., Yu P., MuhammadIqbal S., Yu-Feng Z., Li L. A review on biodegradable materials for cardiovascular stent application. Frontiers of Materials Science. 2016:10(3): 238–259. https://doi.org/10.1007/s11706-016-0344-x.</mixed-citation><mixed-citation xml:lang="en">Li-Da H., Zhen L., Yu P., MuhammadIqbal S., Yu-Feng Z., Li L. A review on biodegradable materials for cardiovascular stent application. Frontiers of Materials Science. 2016:10(3): 238–259. https://doi.org/10.1007/s11706-016-0344-x.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Matteini P., Ratto F., Rossi F., de Angelis M., Cavigli L., Pini R. Hybrid nanocomposite ﬁlms for laser-activated tissue bonding. Journal of Biophotonics. 2012:5(11–12):868–877. https://doi.org/10.1002/jbio.201200115.</mixed-citation><mixed-citation xml:lang="en">Matteini P., Ratto F., Rossi F., de Angelis M., Cavigli L., Pini R. Hybrid nanocomposite ﬁlms for laser-activated tissue bonding. Journal of Biophotonics. 2012:5(11–12):868–877. https://doi.org/10.1002/jbio.201200115.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ark M., Cosman P.H., Boughton P., Dunstan C.R. Photochemical Tissue Bonding (PTB) methods for sutureless tissue adhesion. International Journal of Adhesion and Adhesives. 2016:71:87–98. https://doi.org/10.1016/j.ijadhadh.2016.08.006.</mixed-citation><mixed-citation xml:lang="en">Ark M., Cosman P.H., Boughton P., Dunstan C.R. Photochemical Tissue Bonding (PTB) methods for sutureless tissue adhesion. International Journal of Adhesion and Adhesives. 2016:71:87–98. https://doi.org/10.1016/j.ijadhadh.2016.08.006.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Gerasimenko A.Y., Morozova E.A., Ryabkin D.I., Fayzullin A., Tarasenko S.V., Molodykh V.V., Pyankov E.S., Savelyev M.S., Sorokina E.A., Rogalsky A.Y., Shekhter A., Telyshev D.V. The study of the interaction mechanism between bovine serum albumin and single-walled carbon nanotubes depending on their diameter and concentration in solid nanocomposites by vibrational spectroscopy. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2020:227:117682. https://doi.org/10.3390/bioengineering9060238.</mixed-citation><mixed-citation xml:lang="en">Gerasimenko A.Y., Morozova E.A., Ryabkin D.I., Fayzullin A., Tarasenko S.V., Molodykh V.V., Pyankov E.S., Savelyev M.S., Sorokina E.A., Rogalsky A.Y., Shekhter A., Telyshev D.V. The study of the interaction mechanism between bovine serum albumin and single-walled carbon nanotubes depending on their diameter and concentration in solid nanocomposites by vibrational spectroscopy. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2020:227:117682. https://doi.org/10.3390/bioengineering9060238.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Barry R.M. Book Review: Biomedical Photonics Handbook. Journal of Biomedical Optics. 2003:9(5):1864. https://doi.org/10.1117/1.1776177.</mixed-citation><mixed-citation xml:lang="en">Barry R.M. Book Review: Biomedical Photonics Handbook. Journal of Biomedical Optics. 2003:9(5):1864. https://doi.org/10.1117/1.1776177.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Тарасенко С.В., Благушина Н.А. Гистологическая оценка использования биорезорбируемых коллагеновых мембран при закрытии раневых дефектов слизистой оболочки рта в эксперименте. Вятский медицинский вестник. 2022:1(73):67–75.</mixed-citation><mixed-citation xml:lang="en">Tarasenko, S.V., Blagushina N.A. Histological assessment of the use of bioresorbable collagen membranes in the closure of wound defects of the oral mucosa in an experiment. Vyatka Medical Bulletin. 2022:1:(73):67–75.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Keating S.C., Thomas A.A., Flecknell P.A., Leach M.C. Evaluation of EMLA cream for preventing pain during tattooing of rabbits: Changes in physiological, behavioural and facial expression responses. PLOS ONE. 2012:7(9):e44437. doi:10.1371/journal.pone.0044437.</mixed-citation><mixed-citation xml:lang="en">Keating S.C., Thomas A.A., Flecknell P.A., Leach M.C. Evaluation of EMLA cream for preventing pain during tattooing of rabbits: Changes in physiological, behavioural and facial expression responses. PLOS ONE. 2012:7(9):e44437. doi:10.1371/journal.pone.0044437.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Kramer E.A., Rentschler M.E. Energy-Based Tissue Fusion for Sutureless Closure: Applications, Mechanisms, and Potential for Functional Recovery. Annual Review of Biomedical Engineering. 2018:20:1–20. https://doi.org/10.1146/annurev-bioeng-071516-044702.</mixed-citation><mixed-citation xml:lang="en">Kramer E.A., Rentschler M.E. Energy-Based Tissue Fusion for Sutureless Closure: Applications, Mechanisms, and Potential for Functional Recovery. Annual Review of Biomedical Engineering. 2018:20:1–20. https://doi.org/10.1146/annurev-bioeng-071516-044702.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Pabittei D.R., de Boon W., Heger M., van Golen R.F., Balm R., Legemate D.A., de Mol BA. Laser-assisted vessel welding: state of the art and future outlook. J Clin Transl Res. 2015:30;1(2):1–18. https://doi.org/10.1146/annurev-bioeng-071516-044702.</mixed-citation><mixed-citation xml:lang="en">Pabittei D.R., de Boon W., Heger M., van Golen R.F., Balm R., Legemate D.A., de Mol BA. Laser-assisted vessel welding: state of the art and future outlook. J Clin Transl Res. 2015:30;1(2):1–18. https://doi.org/10.1146/annurev-bioeng-071516-044702.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Ashbell I., Agam N., Katzir A., Basov S., Platkov M., Avital I., Nisky I., Netz U. Laser tissue soldering of the gastrointestinal tract: a systematic review LTS of the gastrointestinal tract. Heliyon. 2023; 9(5): e16018. https://doi.org/10.1016/j.heliyon.2023.e16018.</mixed-citation><mixed-citation xml:lang="en">Ashbell I., Agam N., Katzir A., Basov S., Platkov M., Avital I., Nisky I., Netz U. Laser tissue soldering of the gastrointestinal tract: a systematic review LTS of the gastrointestinal tract. Heliyon. 2023; 9(5): e16018. https://doi.org/10.1016/j.heliyon.2023.e16018.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Гемонов В.В., Лаврова Э.Н., Фалин Л.И. Гистология и эмбриология органов полости рта и зубов. М. : ГЭОТАР-Медиа. 2019:320.ISBN 978-5-9704-5180-9.</mixed-citation><mixed-citation xml:lang="en">Gemonov V.V., Lavrova E.N., Falin L.I. Histology and embryology of the organs of the oral cavity and teeth. Moscow: GEOTAR-Media. 2019:320.ISBN 978-5-9704-5180-9.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Berkovitz B.K., Hoiiand G.R., Moxam B.J. Oral Anatomy, Histology and Embryology. St Louis: Mosby. 2009:416.</mixed-citation><mixed-citation xml:lang="en">Berkovitz B.K., Hoiiand G.R., Moxam B.J. Oral Anatomy, Histology and Embryology. St Louis: Mosby. 2009:416.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Александров М.Т. Лазерная клиническая биофотометрия (теория, эксперимент, практика). М. Техносфера. 2008:581. ISBN 978-5-94836-148-1.</mixed-citation><mixed-citation xml:lang="en">Alexandrov M.T. Laser clinical biophotometry (theory, experiment, practice). M.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Баграмов Р.И., Александров М.Т., Сергеев Ю.Н. Лазеры в стоматологии, челюстно-лицевой хирургии и реконструктивно-пластической хирургии. М. Техносфера. 2010:576. ISBN 978-5-94836-148-2.</mixed-citation><mixed-citation xml:lang="en">Technosphere, 2008:584. ISBN 978-5-94836-148-1.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Минаев В.П., Жилин К.М. Современные лазерные аппараты для хирургии и силовой терапии на основе полупроводниковых и волоконных лазеров: рекомендации по выбору и применению: Научно-техническое объединение «ИРЭ-Полюс». Москва: И.В. Балабанов. 2009:47. ISBN 978-5-91563-037-9. С. 5-11.</mixed-citation><mixed-citation xml:lang="en">Bagramov R.I., Alexandrov M.T., Sergeev Yu.N. Lasers in dentistry, maxillofacial surgery and reconstructive plastic surgery. M. Technosphere. 2010:576. ISBN 978-5-94836-148-2.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Рисованный С.И., Рисованная О.Н., Масычев В.И. Лазерная стоматология. Краснодар: Кубань-Книга. 2005:74-124.</mixed-citation><mixed-citation xml:lang="en">Minaev V.P., Zhilin K.M. Modern laser devices for surgery and power therapy based on semiconductor and ﬁber lasers: recommendations for selection and application: Scientiﬁc and Technical Association «IRE-Polyus». Moscow: I.V. Balabanov. 2009:47. ISBN 978-5-91563-037-9. pp. 5–11.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Тарасенко С.В., Царев В.Н., Гарипов Р.Д., Дьячкова Е.Ю., Репина С.И. Микробиологическое обоснование и эффективность применения эрбиевого и неодимового лазеров у пациентов с воспалительными заболеваниями пародонта и периимплантационных тканей. Клиническая стоматология.</mixed-citation><mixed-citation xml:lang="en">Risovanny S.I., Risovannaya O.N., Masychev V.I. Laser dentistry. Krasnodar: Kuban-Book. 2005:74-124</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Tarasenko S.V., Tsarev V.N., Garipov R.D., Dyachkova E.Yu., Repina S.I. Microbiological justiﬁcation and effectiveness of the use of erbium and neodymium lasers in patients with inﬂammatory periodontal diseases and peri-implantation tissues. Clinical dentistry. 2019:4 (92):41-45.</mixed-citation><mixed-citation xml:lang="en">Tarasenko S.V., Tsarev V.N., Garipov R.D., Dyachkova E.Yu., Repina S.I. Microbiological justiﬁcation and effectiveness of the use of erbium and neodymium lasers in patients with inﬂammatory periodontal diseases and peri-implantation tissues. Clinical dentistry. 2019:4 (92):41-45.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
