<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-1-82-87</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4201</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Ирригация корневых каналов в повседневной эндодонтии</article-title><trans-title-group xml:lang="en"><trans-title>Irrigation of root canals in routine endodontics</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7794-6935</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зорян</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zoryan</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зорян Андрей Владимирович, к.м.н., доцент кафедры терапевтической стоматологии</p></bio><bio xml:lang="en"><p>Zoryan Andrey Vladimirovich, PhD, Associate Professor, Department of Therapeutic Dentistry</p></bio><email xlink:type="simple">andrey_zoryan@mai.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асланова</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Aslanova</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Асланова Альбина Олеговна, врач стоматолог-терапевт, аспирант кафедры терапевтической стоматологии</p></bio><bio xml:lang="en"><p>Aslanova Albina Olegovna, dentist-therapist, postgraduate student of the Department of Therapeutic Dentistry</p></bio><email xlink:type="simple">bunitka_bunitka@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коровкин</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korovkin</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коровкин Иван Андреевич, аспирант кафедры терапевтической стоматологии</p></bio><bio xml:lang="en"><p>Korovkin Ivan Andreevich, Postgraduate Student, Department of Therapeutic Dentistry</p></bio><email xlink:type="simple">I616383@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колганов</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolganov</surname><given-names>G. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Колганов Глеб Сергеевич, аспирант кафедры терапевтической стоматологии</p></bio><bio xml:lang="en"><p>Kolganov Gleb Sergeevich, Postgraduate Student, Department of Therapeutic Dentistry</p></bio><email xlink:type="simple">vakzpetr@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» Министерства науки и высшего образования РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Рeoples Friendship University of Russia named after Patrice Lumumba (RUDN University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>03</day><month>03</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><issue-title>Стоматология (1)</issue-title><fpage>82</fpage><lpage>87</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зорян А.В., Асланова А.О., Коровкин И.А., Колганов Г.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Зорян А.В., Асланова А.О., Коровкин И.А., Колганов Г.С.</copyright-holder><copyright-holder xml:lang="en">Zoryan A.V., Aslanova A.O., Korovkin I.A., Kolganov G.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4201">https://www.med-alphabet.com/jour/article/view/4201</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: аналитический разбор и изучение литературных источников, сравнивающих ирригационные растворы и методы их активации в повседневной эндодонтии.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: в базе данных eLibrary, PubMed, Google Scholar и Meduniver был выполнен запрос научных статей, с использованием ключевых слов: root canal cleaning, sodium hypochlorite, chlorhexidine, ethylenediaminetetraacetic acid, root canal irrigation, activation of irrigation solutions. Таким образом, в данную стать было включено 35 исследовательских работ по теме ирригационных растворов и их активации.</p></sec><sec><title>Результаты</title><p>Результаты: данный аналитический разбор и изучение литературных источников показали, что одним из важнейших факторов в профилактике и лечении эндодонтической патологии является адекватная очистка и ирригация корневого канала, так как в подавляющем большинстве случаев они имеют неправильную форму, многочисленные латеральные, дельтовидные ответвления и анастомозы. Так же достаточно часто встречаются овальные, гантелеобразные или С-образные корневые каналы. В современной эндодонтии в качестве ирригантов повседневно врачи-стоматологи используют натрия гипохлорит, этилендиаминтетрауксусную кислоту и хлоргексидин.</p></sec><sec><title>Вывод</title><p>Вывод: на основании литературных источников было выявлено, что одним из лучших дезинфицирующих растворов для корневых каналов на сегодняшний день является гипохлорит натрия, однако и он не соответствует всем параметрам идеального ирриганта.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: analytical analysis and study of literature sources comparing irrigation solutions and their activation methods in routine endodontics.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: in the eLibrary database, PubMed, Google Scholar and Meduniver requested scientiﬁc articles using the keywords: root canal cleaning, sodium hypochlorite, chlorhexidine, ethylenediaminetetraacetic acid, root canal irrigation, activation of irrigation solutions. Thus, this article included 35 research papers on the topic of irrigation solutions and their activation.</p></sec><sec><title>Results</title><p>Results: this analytical analysis and the study of literary sources have shown that one of the most important factors in the prevention and treatment of endodontic pathology is adequate cleaning and irrigation of the root canal, since in the vast majority of cases they have an irregular shape, numerous lateral, deltoid branches and anastomoses. Oval, dumbbell-shaped or C-shaped root canals are also quite common. In modern endodontics, dentists use sodium hypochlorite, ethylenediaminetetraacetic acid and chlorhexidine as irrigants on a daily basis.</p></sec><sec><title>Conclusion</title><p>Conclusion: based on the literature, it was revealed that one of the best disinfectant solutions for root canals today is sodium hypochlorite, however, it does not meet all the parameters of an ideal irrigant.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>очистка корневых каналов</kwd><kwd>гипохлорит натрия</kwd><kwd>хлоргексидин</kwd><kwd>этилендиаминтетрауксусная кислота</kwd><kwd>ирригация корневых каналов</kwd><kwd>активация ирригационных растворов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>root canal cleaning</kwd><kwd>sodium hypochlorite</kwd><kwd>chlorhexidine</kwd><kwd>ethylenediaminetetraacetic acid</kwd><kwd>root canal irrigation</kwd><kwd>activation of irrigation solutions</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Good M.L., Karim I. A.E., Hussey D.L. Endodontic ‘solutions’ part 1: A literature review on the use of endodontic lubricants, irrigants and medicaments // Dental update. – 2012. – V. 39. – № 4. – P. 239–246.</mixed-citation><mixed-citation xml:lang="en">Good M.L., Karim I. A.E., Hussey D.L. Endodontic ‘solutions’ part 1: A literature review on the use of endodontic lubricants, irrigants and medicaments // Dental update. – 2012. – V. 39. – № 4. – P. 239–246.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Haapasalo M. et al. Irrigation in endodontics // British dental journal. – 2014.</mixed-citation><mixed-citation xml:lang="en">Haapasalo M. et al. Irrigation in endodontics // British dental journal. – 2014.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Бирюкова М.М. и др. Дезінфекція кореневих каналів: методи та засоби: навчально-методичний посібник. – 2016.</mixed-citation><mixed-citation xml:lang="en">Biryukova M. M. et al. Disinfection of root canals: methods and Means: educational and methodical manual.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Neelakantan P. et al. Bioﬁlms in endodontics—current status and future directions // International journal of molecular sciences. – 2017. – V. 18. – № 8. – P. 1748.</mixed-citation><mixed-citation xml:lang="en">Neelakantan P. et al. Bioﬁlms in endodontics—current status and future directions // International journal of molecular sciences. – 2017. – V. 18. – № 8. – P. 1748.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Мазур И.П., Новошицкий В.Е., Хлебас С.В. Медикаментозные средства, применяемые для обработки корневых каналовпри проведении эндодонтического лечения // Стоматология. Эстетика. Инновации. – 2018. – Т. 2. – № 4. – P. 424–432.</mixed-citation><mixed-citation xml:lang="en">Mazur I.P., Novoshitsky V.E., Khlebas S.V. Medicinal products used for root canal treatment during endodontic treatment // Dentistry. Aesthetics. Innovations. – 2018. – V. 2. – No. 4. – P. 424–432.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Sakko M., Tjäderhane L., Rautemaa-Richardson R. Microbiology of root canal infections // Primary dental journal. – 2016. –V. 5. – № 2. – P. 84–89.</mixed-citation><mixed-citation xml:lang="en">Sakko M., Tjäderhane L., Rautemaa-Richardson R. Microbiology of root canal infections // Primary dental journal. – 2016. –V. 5. – № 2. – P. 84–89.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Nogueira B.M.L. et al. Effects of different irrigation solutions and protocols on mineral content and ultrastructure of root canal dentine // Iranian endodontic journal. – 2018. – V. 13. – № 2. – P. 209.</mixed-citation><mixed-citation xml:lang="en">Nogueira B.M.L. et al. Effects of different irrigation solutions and protocols on mineral content and ultrastructure of root canal dentine // Iranian endodontic journal. – 2018. – V. 13. – № 2. – P. 209.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kandaswamy D., Venkateshbabu N. Root canal irrigants //Journal of Conservative Dentistry and Endodontics. – 2010. – V. 13. – № 4. – P. 256–264.</mixed-citation><mixed-citation xml:lang="en">Kandaswamy D., Venkateshbabu N. Root canal irrigants //Journal of Conservative Dentistry and Endodontics. – 2010. – V. 13. – № 4. – P. 256–264.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Baumgartner J. C., Cuenin P. R. Efﬁcacy of several concentrations of sodium hypochlorite for root canal irrigation // Journal of endodontics. – 1992. – V. 18. – № 12. – P. 605-612.</mixed-citation><mixed-citation xml:lang="en">Baumgartner J. C., Cuenin P. R. Efﬁcacy of several concentrations of sodium hypochlorite for root canal irrigation // Journal of endodontics. – 1992. – V. 18. – № 12. – P. 605-612.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Siqueira Jr J. F. et al. Chemomechanical reduction of the bacterial population in the root canal after instrumentation and irrigation with 1%, 2.5%, and 5.25% sodium hypochlorite // Journal of endodontics. – 2000. – V. 26. – № 6. – P. 331–334.</mixed-citation><mixed-citation xml:lang="en">Siqueira Jr J. F. et al. Chemomechanical reduction of the bacterial population in the root canal after instrumentation and irrigation with 1%, 2.5%, and 5.25% sodium hypochlorite // Journal of endodontics. – 2000. – V. 26. – № 6. – P. 331–334.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Berber V.B. et al. Efﬁcacy of various concentrations of NaOCl and instrumentation techniques in reducing Enterococcus faecalis within root canals and dentinal tubules // International endodontic journal. – 2006. – V. 39. – № 1. – P. 10–17.</mixed-citation><mixed-citation xml:lang="en">Berber V.B. et al. Efﬁcacy of various concentrations of NaOCl and instrumentation techniques in reducing Enterococcus faecalis within root canals and dentinal tubules // International endodontic journal. – 2006. – V. 39. – № 1. – P. 10–17.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Reyhani M. F. et al. Antibacterial effect of different concentrations of sodium hypochlorite on Enterococcus faecalis bioﬁlms in root canals //Journal of dental research, dental clinics, dental prospects. – 2017. – V. 11. – № 4. – P. 215.</mixed-citation><mixed-citation xml:lang="en">Reyhani M. F. et al. Antibacterial effect of different concentrations of sodium hypochlorite on Enterococcus faecalis bioﬁlms in root canals //Journal of dental research, dental clinics, dental prospects. – 2017. – V. 11. – № 4. – P. 215.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Farzaneh S. et al. Effect of two different concentrations of sodium hypochlorite on postoperative pain following single-visit root canal treatment: a triple-blind randomized clinical trial // International endodontic journal. – 2018. – V. 51. – С. e2–e11.</mixed-citation><mixed-citation xml:lang="en">Farzaneh S. et al. Effect of two different concentrations of sodium hypochlorite on postoperative pain following single-visit root canal treatment: a triple-blind randomized clinical trial // International endodontic journal. – 2018. – V. 51. – С. e2–e11.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Verma N. et al. Effect of different concentrations of sodium hypochlorite on outcome of primary root canal treatment: a randomized controlled trial // Journal of endodontics. – 2019. – V. 45. – № 4. – P. 357–363.</mixed-citation><mixed-citation xml:lang="en">Verma N. et al. Effect of different concentrations of sodium hypochlorite on outcome of primary root canal treatment: a randomized controlled trial // Journal of endodontics. – 2019. – V. 45. – № 4. – P. 357–363.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gazzaneo I. et al. Root canal disinfection by single-and multiple-instrument systems: effects of sodium hypochlorite volume, concentration, and retention time // Journal of endodontics. – 2019. – V. 45. – № 6. – P. 736–741.</mixed-citation><mixed-citation xml:lang="en">Gazzaneo I. et al. Root canal disinfection by single-and multiple-instrument systems: effects of sodium hypochlorite volume, concentration, and retention time // Journal of endodontics. – 2019. – V. 45. – № 6. – P. 736–741.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Karpiński T.M., Szkaradkiewicz A.K. Chlorhexidine-pharmaco-biological activity and application // Eur Rev Med Pharmacol Sci. – 2015. – V. 19. – № 7. – С. 1321–1326.</mixed-citation><mixed-citation xml:lang="en">Karpiński T.M., Szkaradkiewicz A.K. Chlorhexidine-pharmaco-biological activity and application // Eur Rev Med Pharmacol Sci. – 2015. – V. 19. – № 7. – С. 1321–1326.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Abrar E. et al. Antimicrobial efﬁcacy of silver diamine ﬂuoride in comparison to photodynamic therapy and chlorhexidine on canal disinfection and bond strength to radicular dentin // Photodiagnosis and photodynamic therapy. – 2020. – V. 32. – P. 102066.</mixed-citation><mixed-citation xml:lang="en">Abrar E. et al. Antimicrobial efﬁcacy of silver diamine ﬂuoride in comparison to photodynamic therapy and chlorhexidine on canal disinfection and bond strength to radicular dentin // Photodiagnosis and photodynamic therapy. – 2020. – V. 32. – P. 102066.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Orstavik D. (ed.). Essential endodontology: prevention and treatment of apical periodontitis. – John Wiley &amp; Sons, 2020.</mixed-citation><mixed-citation xml:lang="en">Orstavik D. (ed.). Essential endodontology: prevention and treatment of apical periodontitis. – John Wiley &amp; Sons, 2020.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Lottanti S. et al. Effects of ethylenediaminetetraacetic, etidronic and peracetic acid irrigation on human root dentine and the smear layer // International endodontic journal. – 2009. – V. 42. – № 4. – P. 335–343.</mixed-citation><mixed-citation xml:lang="en">Lottanti S. et al. Effects of ethylenediaminetetraacetic, etidronic and peracetic acid irrigation on human root dentine and the smear layer // International endodontic journal. – 2009. – V. 42. – № 4. – P. 335–343.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Grande N. M. et al. Interaction between EDTA and sodium hypochlorite: a nuclear magnetic resonance analysis //Journal of endodontics. – 2006. – V. 32. – № 5. – С. 460–464.</mixed-citation><mixed-citation xml:lang="en">Grande N. M. et al. Interaction between EDTA and sodium hypochlorite: a nuclear magnetic resonance analysis //Journal of endodontics. – 2006. – V. 32. – № 5. – С. 460–464.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Topbas C., Adiguzel O. Endodontic irrigation solutions: A review: Endodontic irrigation solutions // International Dental Research. – 2017. – V. 7. – № 3. – С. 54–61.</mixed-citation><mixed-citation xml:lang="en">Topbas C., Adiguzel O. Endodontic irrigation solutions: A review: Endodontic irrigation solutions // International Dental Research. – 2017. – V. 7. – № 3. – С. 54–61.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Mohammadi Z. et al. Impact of ultrasonic activation on the effectiveness of sodium hypochlorite: A review // Iranian endodontic journal. – 2015. – V. 10. – № 4. – P. 216.</mixed-citation><mixed-citation xml:lang="en">Mohammadi Z. et al. Impact of ultrasonic activation on the effectiveness of sodium hypochlorite: A review // Iranian endodontic journal. – 2015. – V. 10. – № 4. – P. 216.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Haapasalo M. et al. Irrigation in endodontics // Dental Clinics. – 2010. – V. 54. – № 2. – P. 291–312.</mixed-citation><mixed-citation xml:lang="en">Haapasalo M. et al. Irrigation in endodontics // Dental Clinics. – 2010. – V. 54. – № 2. – P. 291–312.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Shreya S. Chlorhexidine as an irrigant in endodontics-A review //Journal of Pharmaceutical Sciences and Research. – 2016. – V. 8. – № 8. – P. 772.</mixed-citation><mixed-citation xml:lang="en">Shreya S. Chlorhexidine as an irrigant in endodontics-A review //Journal of Pharmaceutical Sciences and Research. – 2016. – V. 8. – № 8. – P. 772.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Bukhari S., Babaeer A. Irrigation in endodontics: a review //Current Oral Health Reports. – 2019. – V. 6. – P. 367–376.</mixed-citation><mixed-citation xml:lang="en">Bukhari S., Babaeer A. Irrigation in endodontics: a review //Current Oral Health Reports. – 2019. – V. 6. – P. 367–376.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Mohammadi Z., Abbott P.V. The properties and applications of chlorhexidine in endodontics // International endodontic journal. – 2009. – V. 42. – № 4. – С. 288–302.</mixed-citation><mixed-citation xml:lang="en">Mohammadi Z., Abbott P.V. The properties and applications of chlorhexidine in endodontics // International endodontic journal. – 2009. – V. 42. – № 4. – С. 288–302.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Mohammadi Z. et al. A Review on Root Canal Irrigation Solutions in Endodontics // Journal of Dental Materials &amp; Techniques. – 2021. – V. 10. – № 3.</mixed-citation><mixed-citation xml:lang="en">Mohammadi Z. et al. A Review on Root Canal Irrigation Solutions in Endodontics // Journal of Dental Materials &amp; Techniques. – 2021. – V. 10. – № 3.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Vahdaty A., Ford T.R. P., Wilson R.F. Efﬁcacy of chlorhexidine in disinfecting dentinal tubules in vitro // Dental Traumatology. – 1993. – V. 9. – № 6. – P. 243–248.</mixed-citation><mixed-citation xml:lang="en">Vahdaty A., Ford T.R. P., Wilson R.F. Efﬁcacy of chlorhexidine in disinfecting dentinal tubules in vitro // Dental Traumatology. – 1993. – V. 9. – № 6. – P. 243–248.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Ercan E. et al. Antibacterial activity of 2% chlorhexidine gluconate and 5.25% sodium hypochlorite in infected root canal: in vivo study // Journal of endodontics. – 2004. – V. 30. – № 2. – P. 84–87.</mixed-citation><mixed-citation xml:lang="en">Ercan E. et al. Antibacterial activity of 2% chlorhexidine gluconate and 5.25% sodium hypochlorite in infected root canal: in vivo study // Journal of endodontics. – 2004. – V. 30. – № 2. – P. 84–87.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Wang C. S. et al. Clinical efﬁciency of 2% chlorhexidine gel in reducing intracanal bacteria // Journal of endodontics. – 2007. – V. 33. – № 11. – P. 1283–1289.</mixed-citation><mixed-citation xml:lang="en">Wang C. S. et al. Clinical efﬁciency of 2% chlorhexidine gel in reducing intracanal bacteria // Journal of endodontics. – 2007. – V. 33. – № 11. – P. 1283–1289.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Gonçalves L. S. et al. The effect of sodium hypochlorite and chlorhexidine as irrigant solutions for root canal disinfection: a systematic review of clinical trials // Journal of endodontics. – 2016. –V. 42. – № 4. – P. 527–532.</mixed-citation><mixed-citation xml:lang="en">Gonçalves L. S. et al. The effect of sodium hypochlorite and chlorhexidine as irrigant solutions for root canal disinfection: a systematic review of clinical trials // Journal of endodontics. – 2016. –V. 42. – № 4. – P. 527–532.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Mohammadi Z. et al. Impact of ultrasonic activation on the effectiveness of sodium hypochlorite: A review // Iranian endodontic journal. – 2015. – V. 10. – № 4. – P. 216.</mixed-citation><mixed-citation xml:lang="en">Mohammadi Z. et al. Impact of ultrasonic activation on the effectiveness of sodium hypochlorite: A review // Iranian endodontic journal. – 2015. – V. 10. – № 4. – P. 216.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Villalta-Briones N. et al. A laboratory study of root canal and isthmus disinfection in extracted teeth using various activation methods with a mixture of sodium hypochlorite and etidronic acid // International endodontic journal. – 2021. – V. 54. – № 2. – P. 268–278.</mixed-citation><mixed-citation xml:lang="en">Villalta-Briones N. et al. A laboratory study of root canal and isthmus disinfection in extracted teeth using various activation methods with a mixture of sodium hypochlorite and etidronic acid // International endodontic journal. – 2021. – V. 54. – № 2. – P. 268–278.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Tonini R. et al. Irrigating solutions and activation methods used in clinical endodontics: a systematic review // Frontiers in oral health. – 2022. – V. 3. – P. 838043.</mixed-citation><mixed-citation xml:lang="en">Tonini R. et al. Irrigating solutions and activation methods used in clinical endodontics: a systematic review // Frontiers in oral health. – 2022. – V. 3. – P. 838043.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Yericyan O. A., Vusataya E. V. Comparative analysis of modern methods of activation of sodium hypochlorite in endodontic treatment //Молодежный инновационный вестник. – 2024. – V. 13. – № S1. – С. 493–497.</mixed-citation><mixed-citation xml:lang="en">Yericyan O. A., Vusataya E. V. Comparative analysis of modern methods of activation of sodium hypochlorite in endodontic treatment //Молодежный инновационный вестник. – 2024. – V. 13. – № S1. – С. 493–497.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
