medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2024-31-42-45medalphabet-4120Research ArticleСтатьиЭпидемиологический анализ кожных форм красной волчанки в городе Москве (2017–2022)Epidemiological analysis of cutaneous forms of lupus erythematosus in Moscow (2017–2022)https://orcid.org/0000-0001-8934-3197МихееваЭ. С.MikheevaE. S.

Михеева Элеонора Станиславовна, аспирант кафедры дерматовенерологии, аллергологии и косметологии

Москва

Mikheeva Eleonora S., postgraduate student at Dept of Dermatovenereology, Allergology and Cosmetology

Moscow

https://orcid.org/0000-0003-2897-3798НовожиловаО. Л.NovozhilovaO. L.

Новожилова Ольга Леонидовна, заместитель главного врача по организационно-методической работе

Москва

Novozhilova Olga L., deputy chief physician for Organizational and Methodological Work

Moscow

https://orcid.org/0000-0001-5723-6573ЖуковаО. В.ZhukovaO. V.

Жукова Ольга Валентиновна, д. м. н., профессор, главный врач МНПЦД ДЗМ; заведующая кафедрой кожных и венерических болезней Медицинскогоинститута

Москва

Zhukova Olga V., DM Sci (habil.), professor, chief physician; head of Dept of Skin and Venereal Diseases of the Medical Institute

Moscow

https://orcid.org/0000-0002-6583-0318КорсунскаяИ. М.KorsunskayaI. M.

Корсунская Ирина Марковна, д. м. н., профессор, зав. лабораторией

Москва

Korsunskaya Irina M., DM Sci (habil.), professor, head of the Laboratory

Moscow

marykor@bk.ruФГАОУ ВО «Российский Университет Дружбы Народов имени Патриса Лумумбы»РоссияPeoples' Friendship University of Russia named after Patrice LumumbaRussian FederationГБУЗ «Московский Центр дерматовенерологии и косметологии»РоссияMoscow Center for Dermatovenereology and CosmetologyRussian FederationФГАОУ ВО «Российский Университет Дружбы Народов имени Патриса Лумумбы»; ГБУЗ «Московский Центр дерматовенерологии и косметологии»РоссияPeoples' Friendship University of Russia named after Patrice Lumumba; Moscow Center for Dermatovenereology and CosmetologyRussian FederationЦентр теоретических проблем. физико-химической фармакологии Российской академии наукРоссияCenter for Theoretical Problems of Physicochemical Pharmacology of the Russian Academy of SciencesRussian Federation202422012025031«Эпидемиология, гигиена, инфекционные болезни» (1)4245Copyright © Михеева Э.С., Новожилова О.Л., Жукова О.В., Корсунская И.М., 20252025Михеева Э.С., Новожилова О.Л., Жукова О.В., Корсунская И.М.Mikheeva E.S., Novozhilova O.L., Zhukova O.V., Korsunskaya I.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/4120

Статья представляет собой всесторонний анализ заболеваемости кожными формами красной волчанки (ККВ) в городе Москве за период с 2017 по 2022 год, подчеркивая динамику и ключевые характеристики распространения данного хронического аутоиммунного заболевания. Красная волчанка (КВ), может проявляться как независимое кожное заболевание или как часть системной красной волчанки (СКВ), с различной вероятностью перехода из одной формы в другую. Исследование освещает специфические клинические формы ККВ, такие как острая, подострая и хроническая кожная волчанка, а также дискоидная волчанка и другие подтипы, обсуждая их вероятность прогрессирования в СКВ. Авторы делают акцент на эпидемиологических аспектах ККВ, указывая на влияние пола, возраста, этнической и расовой принадлежности, а также на роль географических факторов в распространении заболевания. Значительное внимание уделяется потенциальному влиянию инфекции SARS-CoV‑2 и последствиям вакцинации от COVID‑19 на развитие и обострение ККВ, подчеркивая необходимость дополнительных исследований для понимания связи между COVID‑19 и аутоиммунными реакциями. Статья основывается на анализе данных из медицинских баз и ретроспективном обзоре карт пациентов, что позволило авторам заметить стабильный рост заболеваемости ККВ в исследуемый период, особенно среди женщин. Наблюдаемый рост заболеваемости может быть связан с рядом факторов, включая изменения в диагностике, доступности медицинской помощи, а также с пандемией COVID‑19 как возможным провоцирующим фактором. В исследовании подчеркивается важность полученных результатов для медицинского сообщества, акцентируя внимание на необходимости разработки целенаправленных стратегий по диагностике, лечению и контролю ККВ для улучшения качества жизни пациентов. Авторы призывают к будущим исследованиям для глубокого изучения динамики заболеваемости и ее связи с различными факторами, включая пандемию COVID‑19.

The article presents a comprehensive analysis of the incidence of cutaneous forms of lupus erythematosus (CLE) in Moscow for the period from 2017 to 2022, emphasizing the dynamics and key characteristics of the spread of this chronic autoimmune disease. Lupus erythematosus (LE) can manifest as an independent skin disease or as part of systemic lupus erythematosus (SLE), with varying probabilities of transition from one form to the other. The study highlights specific clinical forms of CLE, such as acute, subacute and chronic cutaneous lupus, as well as discoid lupus and other subtypes, discussing their likelihood of progression to SLE. The authors focus on the epidemiological aspects of CLE, pointing out the influence of gender, age, ethnicity and race, as well as the role of geographic factors in the spread of the disease. Considerable attention is paid to the potential impact of SARS-CoV‑2 infection and the effects of COVID‑19 vaccination on the development and exacerbation of CLE, emphasizing the need for additional research to understand the relationship between COVID‑19 and autoimmune reactions. The article is based on the analysis of data from medical databases and a retrospective review of patient charts, which allowed the authors to notice a steady increase in the incidence of CLE during the study period, especially among women. The observed increase in incidence may be associated with a number of factors, including changes in diagnostics, access to medical care, as well as the COVID‑19 pandemic as a possible provoking factor. The study emphasizes the importance of the obtained results for the medical community, focusing on the need to develop targeted strategies for the diagnosis, treatment and control of CLE to improve the quality of life of patients. The authors call for future studies to deeply study the dynamics of the incidence and its relationship with various factors, including the COVID‑19 pandemic.

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The authors declare that there are no conflicts of interest present.