medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2024-24-29-42medalphabet-4012Research ArticleСтатьиВитамин D: что нам известно к 2024 году? Обзор данных о влиянии дополнительного приема витамина D на организм человекаVitamin D: What do we know by 2024? A review of the evidence on the effects of vitamin D supplementation on the human bodyhttps://orcid.org/0000-0002-4689-3591ОрловаС. В.OrlovaS. V.

Орлова Светлана Владимировна, д.м.н., проф., зав. кафедрой диетологии и клинической нутрициологии; главный научный сотрудник

Москва

Orlova Svetlana V., DM Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology; Chief Researcher

Moscow

orlova-sv@rudn.ruhttps://orcid.org/0000-0003-3220-0333НикитинаЕ. А.NikitinaE. A.

Никитина Елена Александровна, к.м.н., доцент кафедры диетологии и клинической нутрициологии; научный сотрудник

Москва

Nikitina Elena A., PhD Med, associate professor at Dept of Dietetics and Clinical Nutrition; Research Fellow; Expert of the Methodological Accreditation and Simulation Center

Moscow

nikitina-ea1@rudn.ruhttps://orcid.org/0000-0002-5203-1082ВодолазкаяА. Н.VodolazkayaA. N.

Водолазкая Ангелина Николаевна, врач-диетолог

Москва

Vodolazkaya Angelina N., dietitian

Moscow

drvodolazkaya@gmail.comhttps://orcid.org/0000-0003-0928-2131БатышеваТ. Т.BatyshevaT. T.

Батышева Татьяна Тимофеевна, д.м.н., проф., заслуженный врач РФ, директор; глав. внештатный детский специалист невролог ДЗМ, глав. внештатный детский специалист по медицинской реабилитации МЗ РФ, зав. кафедрой неврологии, физической, реабилитационной медицины и психологии детского возраста

Москва

Batysheva Tatyana T., DM Sci (habil.), professor, Honored Doctor of the Russian Federation, director; chief pediatric neurologist of the Health Dept of the City of Moscow, chief pediatric specialist in medical rehabilitation of the Ministry of Health of the Russian Federation, head of Dept of Neurology, Physical, Rehabilitation Medicine and Psychology of Childhood

Moscow

https://orcid.org/0000-0001-8448-8493АлексееваМ. В.AlekseevaM. V.

Алексеева Марина Валерьевна, к.м.н., зам. директора по организационнометодической работе

Москва

Alekseeva Marina.V., Ph.D., Deputy Director for Organizational and Methodological Work

Moscow

https://orcid.org/0000-0002-0548-3414БалашоваН. В.BalashovaN. V.

Балашова Наталья Валерьевна, к.б.н., доцент кафедры диетологии и клинической нутрициологии; доцент кафедры клинической лабораторной диагностики факультета усовершенствования врачей

Москва

Author ID: 832745

Balashova Natalya V., PhD Bio, assistant professor at Dept of Clinical Laboratory Diagnostics of the Faculty of Advanced Training of Doctors; assistant professor at Dept of Dietetics and Clinical Nutritiology

Moscow

BalashovaN77@mail.ruhttps://orcid.org/0000-0003-4749-731XПигареваЮ. А.PigarevaYu. A.

Пигарева Юлия Анатольевна, к.м.н., зав. отделением клинической диетологии

Москва

Pigareva Yulia A., PhD Med, head of Dept of Clinical Dietetics

Moscow

1092153068@rudn.ruhttps://orcid.org/0000-0002-3811-9459ПрокопенкоЕ. В.ProkopenkoE. V.

Прокопенко Елена Валерьевна, врач-эндокринолог, диетолог, руководитель отдела развития и сопровождения медицинских информационных систем и сервисов

Москва

Prokopenko Elena V., endocrinologist, dietitian

Moscow

elvprokopenko@gmail.comФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»РоссияPeoples’ Friendship University of Russia named after Patrice Lumumba; Scientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of HealthRussian FederationФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»;ФГБУ «НМИЦ ТПМ» Минздрава РоссииРоссияPeoples’ Friendship University of Russia named after Patrice Lumumba; Scientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of Health; National Medical Research Center for Therapy and Preventive MedicineRussian FederationГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М.Ф. Владимирского»РоссияAustrian clinic of micronutrient therapy BiogenaRussian FederationГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»; ФГАОУ ВО «Российский университет дружбы народов» имени Патриса Лумумбы» (РУДН)РоссияScientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of Health; Peoples’ Friendship University of Russia named after Patrice LumumbaRussian FederationГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»РоссияScientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of HealthRussian FederationФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М.Ф. Владимирского»РоссияPeoples’ Friendship University of Russia named after Patrice Lumumba; MONIKI M.F. Vladimirskii Moscow Regional Scientific Research InstituteRussian FederationГБУЗ «Городская клиническая больница имени В.В. Виноградова Департамента здравоохранения г. Москвы»РоссияCity Clinical Hospital named after V.V. Vinogradov, Moscow City Health DepartmentRussian FederationООО «ИНВИТРО»Россия“INVITRO” Limited Liability CompanyRussian Federation202406122024024Современная поликлиника (2)2942Copyright © Орлова С.В., Никитина Е.А., Водолазкая А.Н., Батышева Т.Т., Алексеева М.В., Балашова Н.В., Пигарева Ю.А., Прокопенко Е.В., 20242024Орлова С.В., Никитина Е.А., Водолазкая А.Н., Батышева Т.Т., Алексеева М.В., Балашова Н.В., Пигарева Ю.А., Прокопенко Е.В.Orlova S.V., Nikitina E.A., Vodolazkaya A.N., Batysheva T.T., Alekseeva M.V., Balashova N.V., Pigareva Y.A., Prokopenko E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/4012

Витамин D играет важную роль в регуляции кальциево-фосфорного обмена, метаболических процессов и клеточного цикла. За прошедшие годы хорошо изучены механизмы молекулярного действия витамина D в различных клетках, органах и тканях. Широкая распространенность дефицита витамина D, установленная на основе лабораторной диагностики, привела к разработке и внедрению программ по коррекции гиповитаминоза D. Однако вопрос о клинической эффективности данных программ остается открытым. В данной статье мы проводим обзор исследований и метаанализов данных, оценивавших профилактическую и лечебную эффективность и безопасность приема физиологических и высоких доз витамина D.

Vitamin D plays an import role in the regulation of calcium-phosphorus metabolism, metabolic processes and the cell cycle.Over the years, the mechanisms of molecular action of vitamin D in various cells, organs and tissues have been well studied. The widespread prevalence of vitamin D deficiency, established on the basis of laboratory diagnostics, has led to the development and implementation of programs for the correction of hypovitaminosis D. However, the question of the clinical effectiveness of these programs remains open. In this article, we review studies and meta-analyses of data that have assessed the preventive and therapeutic efficacy and safety of physiological and high doses of vitamin D.

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The authors declare that there are no conflicts of interest present.