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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-25-34-37</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4009</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Эффективность комплексной топической терапии и широкополосного импульсного некогеретного света в лечении эритематозно-телеангиэктатического подтипа розацеа</article-title><trans-title-group xml:lang="en"><trans-title>Efficiency of complex topical therapy and broadband pulsed non-coherent light in the treatment of erythematotelangiectatic subtype of rosacea</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6452-2914</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсова</surname><given-names>Ж. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusova</surname><given-names>Zh. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юсова Жанна Юрьевна - д.м.н., профессор, профессор кафедры дерматовенерологии и косметологии.</p><p>Москва</p></bio><bio xml:lang="en"><p>Zhanna Yu. Yusova - DM Sci (habil.), professor, professor at Dept of Dermatovenereology and Cosmetology.</p><p>Moscow</p></bio><email xlink:type="simple">zyusova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-4278-193X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казарян</surname><given-names>В. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazaryan</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казарян Валерия Эдуардовна - аспирант кафедры дерматовенерологии и косметологии, проректор по учебной работе.</p><p>Москва</p></bio><bio xml:lang="en"><p>Valeria E. Kazaryan - postgraduate student at Dept of Dermatovenereology and Cosmetology, vice-rector for Academic Affairs.</p><p>Moscow</p></bio><email xlink:type="simple">valeriya.kazaryan@biospher.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5995-6689</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Матушевская</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Matushevskaya</surname><given-names>Yu. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матушевская Юлия Игоревна - к.м.н., главный врач.</p><p>Люберцы, Московская область</p></bio><bio xml:lang="en"><p>Yulia I. Matushevskaya - PhD Med, chief physician.</p><p>Lyubertsy, Moscow Region</p></bio><email xlink:type="simple">yuliya-matushevskaya@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3429-6693</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родина</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Rodina</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Родина Александра Леонидовна - аспирант кафедры дерматовенерологии и косметологии.</p><p>Москва</p></bio><bio xml:lang="en"><p>Alexandra L. Rodina - postgraduate student at Dept of Dermatovenereology and Cosmetology.</p><p>Moscow</p></bio><email xlink:type="simple">al.rodina@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy of the Administrative Department of the President of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ МО «Люберецкий кожно-венерологический диспансер»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Lyubertsy Skin and Venereal Diseases Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>05</day><month>12</month><year>2024</year></pub-date><volume>0</volume><issue>25</issue><issue-title>Дерматология (2)</issue-title><fpage>34</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Юсова Ж.Ю., Казарян В.Э., Матушевская Ю.И., Родина А.Л., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Юсова Ж.Ю., Казарян В.Э., Матушевская Ю.И., Родина А.Л.</copyright-holder><copyright-holder xml:lang="en">Yusova Z.Y., Kazaryan V.E., Matushevskaya Y.I., Rodina A.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4009">https://www.med-alphabet.com/jour/article/view/4009</self-uri><abstract><p>Розацеа представляет собой хронический воспалительный дерматоз фациальной локализации. Тактика лечения больных розацеа представляет сложную задачу, поскольку зависит от степени тяжести и индивидуальных особенностей пациента. Многочисленность исследований определяет актуальность данной проблемы. Наблюдение за 22 пациентами, 11 из которых получали только топическое лечение с эритематозно-телеангиэктатическим подтипом розацеа лечение в виде 15 % азелаиновой кислоты, 0,5 % геля бримонидина тартрата. У 11 других пациентов топическое лечение комбинировали с фототерапией – широкополосным некогерентным импульсным светом с интервалом 1 раз в 4 недели, 3 процедуры на курс. Оценка эффективности терапии проводилась при помощи аппарата 3D-визуализации и диагностики кожи «Antera». Также в качестве клинических методов оценки использовались дерматологический индекc GSS (Global Severity Score) и дерматологический индекс шкалы симптомов (ДИШС). Комбинация применения 15 % азелаиновой кислоты, 0,5 % геля бримонидина тартрата с широкополосной импульсной терапией (3 процедуры) показала более высокую эффективность, чем монотерапия топическими средствами. Полученные результаты, свидетельствующие о более высокой эффективности сочетанной методики лечения, можно объяснить синергичным эффектом комбинации физиотерапевтического фактора и наружных препаратов, влияющих на патогенетические механизмы развития заболевания.</p></abstract><trans-abstract xml:lang="en"><p>Rosacea is a chronic inflammatory dermatosis of facial localization. Treatment tactics for patients with rosacea is a complex task, since it depends on the severity and individual characteristics of the patient. Numerous studies determine the relevance of this problem. Observation of 22 patients, 11 of whom received only topical treatment with the erythematotelangiectatic subtype of rosacea treatment in the form of 15% azelaic acid, 0.5 % brimonidine tartrate gel, and 1 % metronidazole cream. In 11 other patients, topical treatment was combined with phototherapy – broadband incoherent pulsed light at intervals of 1 time in 4 weeks, 3 procedures per course. Evaluation of the effectiveness of therapy was carried out using the Antera 3D visualization and skin diagnostics device. Also, the dermatological index GSS (Global Severity Score) and the dermatological index of symptom scale (DISS) were used as clinical evaluation methods. The combination of 15 % azelaic acid, 0.5 % brimonidine tartrate gel, with broadband pulse therapy (3 procedures) showed higher efficiency than monotherapy with topical agents. The obtained results, indicating higher efficiency of the combined treatment method, can be explained by the synergistic effect of the combination of the physiotherapeutic factor and external drugs affecting the pathogenetic mechanisms of disease development.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>розацеа</kwd><kwd>фототерапия</kwd><kwd>азелаиновая кислота</kwd><kwd>бримонидина тартрат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rosacea</kwd><kwd>phototherapy</kwd><kwd>azelaic acid</kwd><kwd>brimonidine tartrate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Акимов В. Г., Круглова Л. С. Дифференциальная диагностика розацеа.– Российский журнал кожных и венерических болезней.– 2020.– Т. 23.– № 1.– C. 50–56.</mixed-citation><mixed-citation xml:lang="en">Akimov V. G., Kruglova L. S. 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