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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-21-57-62</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3957</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Варианты стойкой обонятельной дисфункции, ассоциированной с новой коронавирусной инфекцией, и результаты лечения</article-title><trans-title-group xml:lang="en"><trans-title>Variants of persistent olfactory dysfunction associated with Novel Coronavirus infection and treatment results</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Адамова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Adamova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Адамова Анастасия Сергеевна - аспирант III года обучения на кафедре неврологии имени академика С.Н. Давиденкова.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Anastasia S. Adamova - 3rd year postgraduate student at Dept of Neurology n. a. academician S.N. Davidenkov.</p><p>Saint Petersburg</p></bio><email xlink:type="simple">adamowa.anastasya@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6814-0454</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клочева</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Klocheva</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клочева Елена Георгиевна - д. м. н., проф.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Elena G. Klocheva - DM Sci (habil.), professor.</p><p>Saint Petersburg</p></bio><email xlink:type="simple">klocheva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9245-8067</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голдобин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Goldobin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Голдобин Виталий Витальевич - д. м. н., зав. кафедрой неврологии имени академика С.Н. Давиденкова.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Vitaly V. Goldobin - DM Sci (habil.), head of Dept of Neurology n. a. academician S.N. Davidenkov.</p><p>Saint Petersburg</p></bio><email xlink:type="simple">vitalii.goldobin@szgmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University n. a. I.I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>08</day><month>11</month><year>2024</year></pub-date><volume>0</volume><issue>21</issue><issue-title>Неврология и психиатрия (3)</issue-title><fpage>57</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Адамова А.С., Клочева Е.Г., Голдобин В.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Адамова А.С., Клочева Е.Г., Голдобин В.В.</copyright-holder><copyright-holder xml:lang="en">Adamova A.S., Klocheva E.G., Goldobin V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3957">https://www.med-alphabet.com/jour/article/view/3957</self-uri><abstract><p>Проблема возникновения стойкой обонятельной дисфункции (ОД), ассоциированной с новой коронавирусной инфекцией (COVID-19), в настоящее время приобрела актуальное значение, однако регламентированного стандарта терапии не разработано. По данным литературы, около 60 % пациентов отмечают наличие обонятельных нарушений, сохраняющихся от нескольких месяцев и более после выздоровления от COVID-19. Однако за медицинской помощью по поводу обонятельных нарушений обращается не более 5 %, что обозначает значимость проблемы и необходимость лечения в условиях поликлинического звена. В настоящее время используются два основных направления лечения количественных и качественных нарушений обоняния – медикаментозная и немедикаментозная терапия. В статье предложен вариант систематизации на базе существующих методов лечения с оценкой их эффективности. Описана методика выполнения обонятельной тренировки, а также представлены результаты лечения стойкой ОД.</p></abstract><trans-abstract xml:lang="en"><p>The problem of the occurrence of persistent olfactory dysfunction (OD) associated with Novel Coronavirus infection (COVID-19) has now become relevant, however, a regulated standard of therapy has not been developed. According to the literature, about 60 % of patients report the presence of olfactory disorders that persist for several months or more after recovery from COVID-19. However, no more than 5 % seek medical help for olfactory disorders, which indicates the importance of the problem and the need for treatment in a polyclinic setting. Currently, two main areas of treatment for quantitative and qualitative disorders of the sense of smell are used – drug and non-drug therapy. The article proposes a systematization option based on existing treatment methods with an assessment of their effectiveness. The method of performing olfactory training is described, and the results of treatment of persistent OD are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стойкая обонятельная дисфункция</kwd><kwd>COVID-19</kwd><kwd>Sniffin’ Stick тест</kwd><kwd>интраназальные кортикостероиды</kwd><kwd>сульфат цинка</kwd><kwd>витамин А</kwd><kwd>цитрат натрия</kwd><kwd>интраназальный инсулин</kwd><kwd>обонятельная тренировка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>persistent olfactory dysfunction</kwd><kwd>COVID-19</kwd><kwd>Sniffin' Sticks Test</kwd><kwd>Intranasal Corticosteroids</kwd><kwd>Zinc Sulfate</kwd><kwd>vitamin A</kwd><kwd>Sodium citrate</kwd><kwd>Intranasal insulin</kwd><kwd>olfactory training</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Killingley B., Mann A. J., Kalinova M. et al. 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