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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-16-69-72</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3845</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Влияние различных дозировок кофеина на скоростно-силовые параметры борцов вольного стиля: пилотное исследование</article-title><trans-title-group xml:lang="en"><trans-title>Effect of different doses of caffeine on speed and strength parameters of freestyle wrestlers: a pilot study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1165-6518</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыбакова</surname><given-names>П. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Rybakova</surname><given-names>P. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рыбакова Полина Денисовна, аналитик отдела спортивной нутрициологии, аспирант кафедры спортивной медицины</p><p>Москва</p></bio><bio xml:lang="en"><p>Rybakova Polina D., analyst at Dept of Sports Nutritionology, postgraduate student of Dept of Sports Medicine</p><p>Moscow</p></bio><email xlink:type="simple">rybakova.poly@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3409-4485</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антонов</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Antonov</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Антонов Алексей Геннадьевич, аналитик отдела спортивной нутрициологии, аспирант кафедры спортивной медицины</p><p>Москва</p></bio><bio xml:lang="en"><p>Antonov Alexey G., analyst at Dept of Sports Nutritionology, postgraduate student of Dept of Sports Medicine</p><p>Moscow</p></bio><email xlink:type="simple">alexantonovk@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4030-0302</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирошников</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Miroshnikov</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мирошников Александр Борисович, д. б. н., доцент, проф. кафедры спортивной медицины, декан факультета адаптивной физической культуры, рекреации и туризма</p><p>Москва</p></bio><bio xml:lang="en"><p>Miroshnikov Alexander B., Dr Bio Sci, associate professor, professor of Dept of Sports Medicine, dean of the Faculty of Adaptive Physical Culture, Recreation and Tourism</p><p>Moscow</p></bio><email xlink:type="simple">benedikt116@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГКУ города Москвы «Центр спортивных инновационных технологий и подготовки сборных команд» Департамента спорта города Москвы; ФГБОУ ВО «Российский университет спорта “ГЦОЛИФК”»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Sports Innovative Technologies and training of National Teams; Russian University of Sports “GTSOLIFK”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Российский университет спорта “ГЦОЛИФК”»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian University of Sports “GTSOLIFK”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>05</day><month>09</month><year>2024</year></pub-date><volume>0</volume><issue>16</issue><issue-title>Диетология и нутрициология</issue-title><fpage>69</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рыбакова П.Д., Антонов А.Г., Мирошников А.Б., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Рыбакова П.Д., Антонов А.Г., Мирошников А.Б.</copyright-holder><copyright-holder xml:lang="en">Rybakova P.D., Antonov A.G., Miroshnikov A.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3845">https://www.med-alphabet.com/jour/article/view/3845</self-uri><abstract><p>Постоянно растущая конкуренция в единоборствах требует внедрения оптимальных факторов нутритивно-метаболической поддержки. Среди популярных биологически активных добавок кофеин является одним из наиболее потребляемых веществ в мире спорта и признан эргогенным агентом.Цель. Оценка влияния различных дозировок биологически активной добавки кофеина на скоростно-силовые параметры работоспособности у борцов вольного стиля.Методы. В перекрестное исследование вошло 5 высококвалифицированных спортсменов, занимающихся вольной борьбой. Были определены генетические вариации фермента CYP1A2. Двойным слепым методом участники принимали за 60 мин. до тестирования: плацебо; кофеин: 6 мг/кг массы тела, 3 мг/кг массы тела и 1,5 мг/кг массы тела. Участники выполняли 30-секундный Вингейтский анаэробный тест на ручном эргометре. Регистрировались показатели кислородного запроса и кислородного долга с помощью газоанализатора, фиксировался уровень лактата крови через 3, 5 и 7 мин. после окончания теста.Результаты. Прием кофеина по протоколу 1,5 мг/кг массы тела не показал различий в сравнении с плацебо. Прием кофеина по протоколу 3 мг/кг массы тела снизил показатели потребления кислорода, в то время как остальные параметры не были изменены. Прием кофеина по протоколу 6 мг/кг массы тела не привел к изменению времени достижения максимальной мощности, параметров потребления кислорода, однако снизились параметры мощности. Лактат крови при приеме плацебо был увеличен на 7-й мин. работы в сравнении с 3-й мин. Прием кофеина в дозировке 1,5 мг/кг массы тела привел к значительному увеличению лактата в сравнении с 3-й мин., однако изменения не были статистически значимыми. Дозировка кофеина 3 мг/кг массы тела привела к увеличению лактата в сравнении с 3-й и 5-й мин. Прием кофеина в дозировке 6 мг/кг массы тела показал снижение до его исходного уровня на 7-й мин.Выводы. Борцы не улучшали скоростно-силовые показатели работоспособности и восстановления после приема кофеина в 30-секундном Вингейтском анаэробном тесте на ручном эргометре.</p></abstract><trans-abstract xml:lang="en"><p>The ever-increasing competition in combat sports requires the introduction of optimal nutritional and metabolic support factors. Among popular supplements, caffeine is one of the most consumed substances in the world of sport and is recognised as an ergogenic agent.Objective. To evaluate the effect of different doses of biologically active caffeine supplement on speed and strength performance parameters in freestyle wrestlers.Methods. A cross-sectional study included 5 highly qualified athletes involved in freestyle wrestling. Genetic variations of the CYP1A2 enzyme were determined. In a double-blind method, participants took 60 minutes before testing: placebo; caffeine: 6 mg/kg body weight, 3 mg/kg body weight, and 1.5 mg/kg body weight. Participants performed a 30-second Wingate anaerobic test on a manual ergometer. Oxygen demand and oxygen debt were recorded using a gas analyzer, and blood lactate levels were recorded at 3, 5 and 7 minutes after the end of the test.Results. Caffeine ingestion according to the protocol of 1.5 mg/kg body weight showed no differences compared to placebo. Caffeine administration under the protocol 3 mg/kg body weight decreased oxygen consumption values, while the other parameters were not changed. Caffeine administration under the protocol of 6 mg/kg body weight did not change the time to reach maximal power, oxygen consumption parameters, but power parameters were decreased. Blood lactate was increased at the 7th minute of running compared to the 3rd minute when taking placebo. Caffeine administration at a dosage of 1.5 mg/kg body weight resulted in a significant increase in lactate compared to the 3rd minute, but the changes were not statistically significant. A caffeine dosage of 3 mg/kg body weight resulted in an increase in lactate compared to the 3rd and 5th minute. Caffeine administration at a dosage of 6 mg/kg body weight showed a decrease to its baseline level at the 7th minute.Conclusions. Wrestlers did not improve speed and strength performance and recovery after caffeine ingestion in the 30-second Wingate anaerobic manual ergometer test.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>кофеин</kwd><kwd>эргогенная помощь</kwd><kwd>работоспособность</kwd><kwd>вольная борьба</kwd><kwd>тест Вингейт</kwd><kwd>скоростно-силовые параметры</kwd></kwd-group><kwd-group xml:lang="en"><kwd>caffeine</kwd><kwd>ergogenic assistance</kwd><kwd>performance</kwd><kwd>freestyle wrestling</kwd><kwd>Wingate test</kwd><kwd>speed</kwd><kwd>and strength parameter</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Vasconcelos BB, Protzen GV, Galliano LM, Kirk C, Del Vecchio FB. Effects of High-Intensity Interval Training in Combat Sports: A Systematic Review with Meta-Analysis. J. Strength Cond. Res. 2020; 34: 888–900. DOI: 10.1519/JSC.0000000000003255</mixed-citation><mixed-citation xml:lang="en">Vasconcelos BB, Protzen GV, Galliano LM, Kirk C, Del Vecchio FB. Effects of High-Intensity Interval Training in Combat Sports: A Systematic Review with Meta-Analysis. J. Strength Cond. Res. 2020; 34: 888–900. DOI: 10.1519/JSC.0000000000003255</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bridge CA, Ferreira da Silva Santos J, Chaabène H, Pieter W, Franchini E. Physical and physiological profiles of taekwondo athletes. Sports Med. 2014; 44: 713–733. DOI: 10.1007/s40279-014-0159-9</mixed-citation><mixed-citation xml:lang="en">Bridge CA, Ferreira da Silva Santos J, Chaabène H, Pieter W, Franchini E. Physical and physiological profiles of taekwondo athletes. Sports Med. 2014; 44: 713–733. DOI: 10.1007/s40279-014-0159-9</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Lebron MA, Stout JR, Fukuda DH. Physiological Perturbations in Combat Sports: Weight Cycling and Metabolic Function – A Narrative Review. Metabolites. 2024; 14 (2): 83. https://doi.org/10.3390/metabo14020083</mixed-citation><mixed-citation xml:lang="en">Lebron MA, Stout JR, Fukuda DH. Physiological Perturbations in Combat Sports: Weight Cycling and Metabolic Function – A Narrative Review. Metabolites. 2024; 14 (2): 83. https://doi.org/10.3390/metabo14020083</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Del Coso J, Munoz G, Munoz-Guerra J. Prevalence of caffeine use in elite athletes following its removal from the World Anti-Doping Agency list of banned substances. Appl. Physiol. Nutr. Metab. 2011; 36: 555–561. DOI: 10.1139/h11–052</mixed-citation><mixed-citation xml:lang="en">Del Coso J, Munoz G, Munoz-Guerra J. Prevalence of caffeine use in elite athletes following its removal from the World Anti-Doping Agency list of banned substances. Appl. Physiol. Nutr. Metab. 2011; 36: 555–561. DOI: 10.1139/h11–052</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Guest NS, VanDusseldorp TA, Nelson MT, Grgic J, Schoenfeld BJ, Jenkins NDM, Arent SM, Antonio J, Stout JR, Trexler ET. International society of sports nutrition position stand: Caffeine and exercise performance. J. Int. Soc. Sports Nutr. 2021; 18: 1. DOI: 10.1186/s12970-020-00383-4</mixed-citation><mixed-citation xml:lang="en">Guest NS, VanDusseldorp TA, Nelson MT, Grgic J, Schoenfeld BJ, Jenkins NDM, Arent SM, Antonio J, Stout JR, Trexler ET. International society of sports nutrition position stand: Caffeine and exercise performance. J. Int. Soc. Sports Nutr. 2021; 18: 1. DOI: 10.1186/s12970-020-00383-4</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Delleli S, Ouergui I, Messaoudi H, Trabelsi K, Ammar A, Glenn JM, Chtourou H. Acute Effects of Caffeine Supplementation on Physical Performance, Physiological Responses, Perceived Exertion, and Technical-Tactical Skills in Combat Sports: A Systematic Review and Meta-Analysis. Nutrients. 2022; 14 (14): 2996. DOI: 10.3390/nu14142996</mixed-citation><mixed-citation xml:lang="en">Delleli S, Ouergui I, Messaoudi H, Trabelsi K, Ammar A, Glenn JM, Chtourou H. Acute Effects of Caffeine Supplementation on Physical Performance, Physiological Responses, Perceived Exertion, and Technical-Tactical Skills in Combat Sports: A Systematic Review and Meta-Analysis. Nutrients. 2022; 14 (14): 2996. DOI: 10.3390/nu14142996</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Vicente-Salar N, Fuster-Muñoz E, Martínez-Rodríguez A. Nutritional Ergogenic Aids in Combat Sports: A Systematic Review and Meta-Analysis. Nutrients. 2022; 14 (13): 2588. DOI: 10.3390/nu14132588</mixed-citation><mixed-citation xml:lang="en">Vicente-Salar N, Fuster-Muñoz E, Martínez-Rodríguez A. Nutritional Ergogenic Aids in Combat Sports: A Systematic Review and Meta-Analysis. Nutrients. 2022; 14 (13): 2588. DOI: 10.3390/nu14132588</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Wang B, Zhou SF. Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr. Med. Chem. 2009; 16 (31): 4066-4218</mixed-citation><mixed-citation xml:lang="en">Wang B, Zhou SF. Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr. Med. Chem. 2009; 16 (31): 4066-4218</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Yang A, Palmer AA, de Wit H. Genetics of caffeine consumption and responses to caffeine // Psychopharmacology (Berl). 2010; 211 (3): 245–57. DOI: 10.1007/s00213-010-1900-1</mixed-citation><mixed-citation xml:lang="en">Yang A, Palmer AA, de Wit H. Genetics of caffeine consumption and responses to caffeine // Psychopharmacology (Berl). 2010; 211 (3): 245–57. DOI: 10.1007/s00213-010-1900-1</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Harriss DJ, MacSween A, Atkinson G. Ethical Standards in Sport and Exercise Science Research: 2020 Update. Int J. Sports Med. 2019; 40 (13): 813–817. DOI: 10.1055/a‑1015-3123</mixed-citation><mixed-citation xml:lang="en">Harriss DJ, MacSween A, Atkinson G. Ethical Standards in Sport and Exercise Science Research: 2020 Update. Int J. Sports Med. 2019; 40 (13): 813–817. DOI: 10.1055/a‑1015-3123</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Nehlig A. Inter individual differences in caffeine metabolism and factors driving caffeine consumption. Pharmacol Rev. 2018; 70: 384–411. DOI: 10.1124/pr.117.014407</mixed-citation><mixed-citation xml:lang="en">Nehlig A. Inter individual differences in caffeine metabolism and factors driving caffeine consumption. Pharmacol Rev. 2018; 70: 384–411. DOI: 10.1124/pr.117.014407</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Sachse C, Brockmöller J, Bauer S, Roots I. Functional significance of a C—&gt;A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine // Br. J. Clin. Pharmacol. 1999; 47 (4): 445–9. DOI: 10.1046/j.1365–2125.1999.00898.x</mixed-citation><mixed-citation xml:lang="en">Sachse C, Brockmöller J, Bauer S, Roots I. Functional significance of a C—&gt;A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine // Br. J. Clin. Pharmacol. 1999; 47 (4): 445–9. DOI: 10.1046/j.1365–2125.1999.00898.x</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Grgic J, Grgic I, Pickering C, Schoenfeld BJ, Bishop DJ, Pedisic Z. Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses. Br. J. Sports Med. 2020; 54 (11): 681–688. DOI: 10.1136/bjsports‑2018-100278</mixed-citation><mixed-citation xml:lang="en">Grgic J, Grgic I, Pickering C, Schoenfeld BJ, Bishop DJ, Pedisic Z. Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses. Br. J. Sports Med. 2020; 54 (11): 681–688. DOI: 10.1136/bjsports‑2018-100278</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Valiño-Marques A, Lamas A, Miranda JM, Cepeda A, Regal P. Nutritional Ergogenic Aids in Cycling: A Systematic Review. Nutrients. 2024; 16 (11): 1768. DOI: 10.3390/nu16111768</mixed-citation><mixed-citation xml:lang="en">Valiño-Marques A, Lamas A, Miranda JM, Cepeda A, Regal P. Nutritional Ergogenic Aids in Cycling: A Systematic Review. Nutrients. 2024; 16 (11): 1768. DOI: 10.3390/nu16111768</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang Y, Diao P, Wang J, Li S, Fan Q, Han Y, Liang Y, Wang Z, Del Coso J. The Effect of Post-Activation Potentiation Enhancement Alone or in Combination with Caffeine on Anaerobic Performance in Boxers: A Double-Blind, Randomized Crossover Study. Nutrients. 2024; 16 (2): 235. DOI: 10.3390/nu16020235</mixed-citation><mixed-citation xml:lang="en">Zhang Y, Diao P, Wang J, Li S, Fan Q, Han Y, Liang Y, Wang Z, Del Coso J. The Effect of Post-Activation Potentiation Enhancement Alone or in Combination with Caffeine on Anaerobic Performance in Boxers: A Double-Blind, Randomized Crossover Study. Nutrients. 2024; 16 (2): 235. DOI: 10.3390/nu16020235</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Rahimi MR, Semenova EA, John G, Fallah F, Larin AK, Generozov EV, Ahmetov II. Effect of ADORA2A Gene Polymorphism and Acute Caffeine Supplementation on Hormonal Response to Resistance Exercise: A Double-Blind, Crossover, Placebo-Controlled Study. Nutrients. 2024; 16 (12): 1803. DOI: 10.3390/nu16121803</mixed-citation><mixed-citation xml:lang="en">Rahimi MR, Semenova EA, John G, Fallah F, Larin AK, Generozov EV, Ahmetov II. Effect of ADORA2A Gene Polymorphism and Acute Caffeine Supplementation on Hormonal Response to Resistance Exercise: A Double-Blind, Crossover, Placebo-Controlled Study. Nutrients. 2024; 16 (12): 1803. DOI: 10.3390/nu16121803</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Grgic J, Pickering C, Del Coso J, Schoenfeld BJ, Mikulic P. CYP1A2 genotype and acute ergogenic effects of caffeine intake on exercise performance: a systematic review. Eur. J. Nutr. 2021; 60 (3): 1181–1195. DOI: 10.1007/s00394-020-02427-6</mixed-citation><mixed-citation xml:lang="en">Grgic J, Pickering C, Del Coso J, Schoenfeld BJ, Mikulic P. CYP1A2 genotype and acute ergogenic effects of caffeine intake on exercise performance: a systematic review. Eur. J. Nutr. 2021; 60 (3): 1181–1195. DOI: 10.1007/s00394-020-02427-6</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Kocatürk RR, Karagöz İ, Yanik E, Özcan ÖÖ, Ergüzel TT, Karahan M, Tarhan N. The effects of CYP1A2 and ADORA2A genotypes association with acute caffeine intake on physiological effects and performance: A systematic review. Baltic Journal of Health and Physical Activity. 2022; 14 (3): 8. DOI: 10.29359/BJHPA.14.3.08</mixed-citation><mixed-citation xml:lang="en">Kocatürk RR, Karagöz İ, Yanik E, Özcan ÖÖ, Ergüzel TT, Karahan M, Tarhan N. The effects of CYP1A2 and ADORA2A genotypes association with acute caffeine intake on physiological effects and performance: A systematic review. Baltic Journal of Health and Physical Activity. 2022; 14 (3): 8. DOI: 10.29359/BJHPA.14.3.08</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Marinho AH, Lopes-Silva JP, Cristina-Souza G, Sousa FAB, Ataide-Silva T, Lima-Silva AE, Araujo GG, Silva-Cavalcante MD. Effects of caffeine ingestion on cardiopulmonary responses during a maximal graded exercise test: a systematic review with meta-analysis and meta-regression. Crit. Rev. Food. Sci. Nutr. 2024; 64 (1): 127–139. DOI: 10.1080/10408398.2022.2104807</mixed-citation><mixed-citation xml:lang="en">Marinho AH, Lopes-Silva JP, Cristina-Souza G, Sousa FAB, Ataide-Silva T, Lima-Silva AE, Araujo GG, Silva-Cavalcante MD. Effects of caffeine ingestion on cardiopulmonary responses during a maximal graded exercise test: a systematic review with meta-analysis and meta-regression. Crit. Rev. Food. Sci. Nutr. 2024; 64 (1): 127–139. DOI: 10.1080/10408398.2022.2104807</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Wang J, Dewi L, Peng Y, Hou CW, Song Y, Condello G. Does ergogenic effect of caffeine supplementation depend on CYP1A2 genotypes? A systematic review with meta-analysis. J. Sport Health Sci. 2024; 13 (4): 499–508. Doi: 10.1016/j.jshs.2023.12.005</mixed-citation><mixed-citation xml:lang="en">Wang J, Dewi L, Peng Y, Hou CW, Song Y, Condello G. Does ergogenic effect of caffeine supplementation depend on CYP1A2 genotypes? A systematic review with meta-analysis. J. Sport Health Sci. 2024; 13 (4): 499–508. Doi: 10.1016/j.jshs.2023.12.005</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Guest NS, VanDusseldorp TA, Nelson MT, Grgic J, Schoenfeld BJ, Jenkins NDM, Arent SM, Antonio J, Stout JR, Trexler ET, Smith-Ryan AE, Goldstein ER, Kalman DS, Campbell BI. International society of sports nutrition position stand: caffeine and exercise performance. J. Int Soc Sports Nutr. 2021; 18 (1): 1. DOI: 10.1186/s12970-020-00383-4</mixed-citation><mixed-citation xml:lang="en">Guest NS, VanDusseldorp TA, Nelson MT, Grgic J, Schoenfeld BJ, Jenkins NDM, Arent SM, Antonio J, Stout JR, Trexler ET, Smith-Ryan AE, Goldstein ER, Kalman DS, Campbell BI. International society of sports nutrition position stand: caffeine and exercise performance. J. Int Soc Sports Nutr. 2021; 18 (1): 1. DOI: 10.1186/s12970-020-00383-4</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
