<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-16-65-68</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3844</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Влияние физической нагрузки на мозговой натрийуретический пептид при различных состояниях сердечно-сосудистой системы: обзор предметного поля</article-title><trans-title-group xml:lang="en"><trans-title>The effect of physical activity on the brain natriuretic peptide in various conditions of the cardiovascular system: a review of the subject field</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4982-5615</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мештель</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Meshtel</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мештель Александр Виталиевич, аспирант кафедры спортивной медицины, ассистент кафедры анатомии и биологической антропологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Meshtel Alexander V., postgraduate student of Dept of Sports Medicine, assistant at Dept of Anatomy and Biological Anthropology</p><p>Moscow</p></bio><email xlink:type="simple">meshtel.author@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4030-0302</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирошников</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Miroshnikov</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мирошников Александр Борисович, д. б. н., доцент, декан факультета адаптивной физической культуры, рекреации и туризма, проф. кафедры спортивной медицины</p><p>Москва</p></bio><bio xml:lang="en"><p>Miroshnikov Alexander B., Dr Bio Sci, associate professor, dean of the Faculty of Adaptive Physical Culture, Recreation and Tourism, professor at Dept of Sports Medicine</p><p>Moscow</p></bio><email xlink:type="simple">benedikt116@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5663-9936</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смоленский</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smolensky</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Смоленский Андрей Вадимович, академик РАЕН, д. м. н., проф., зав. кафедрой спортивной медицины</p><p>Москва</p></bio><bio xml:lang="en"><p>Smolensky Andrey V., academician of the Russian Academy of Natural Sciences, DM Sci (habil.), professor, head of Dept of Sports Medicine</p><p>Moscow</p></bio><email xlink:type="simple">chair.sportmed@gtsolifk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Российский университет спорта “ГЦОЛИФК”»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian University of Sports “GTSOLIFK”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>05</day><month>09</month><year>2024</year></pub-date><volume>0</volume><issue>16</issue><issue-title>Диетология и нутрициология</issue-title><fpage>65</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мештель А.В., Мирошников А.Б., Смоленский А.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Мештель А.В., Мирошников А.Б., Смоленский А.В.</copyright-holder><copyright-holder xml:lang="en">Meshtel A.V., Miroshnikov A.B., Smolensky A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3844">https://www.med-alphabet.com/jour/article/view/3844</self-uri><abstract><p>В данном обзоре предметного поля рассматриваются мозговой натрийуретический пептид и его предшественник – N-концевой про- мозговой натрийуретический пептид – как маркер для оценки эффективности реабилитационных программ, включающих физические нагрузки, при таких заболеваниях, как артериальная гипертензия, хроническая сердечная недостаточность, ишемическая болезнь сердца и др. Кроме того, рассматривается реакция данного пептида на физическую нагрузку у здоровых людей.</p></abstract><trans-abstract xml:lang="en"><p>In this review of the subject field, the brain natriuretic peptide and its predecessor, the N-terminal pro-brain natriuretic peptide, are considered as a marker for evaluating the effectiveness of rehabilitation programs, including physical activity, in diseases such as arterial hypertension, chronic heart failure, coronary heart disease and other diseases. In addition, the reaction of this peptide to physical activity in healthy people is considered.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мозговой натрийуретический пептид</kwd><kwd>кардиореабилитация</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>физическая реабилитация</kwd><kwd>хроническая сердечная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>brain natriuretic peptide</kwd><kwd>cardiorehabilitation</kwd><kwd>coronary heart disease</kwd><kwd>physical rehabilitation</kwd><kwd>chronic heart failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Simão A. F., Précoma D. B., de Andrade J. P., Filho H. C., Saraiva J. F.K., Oliveira G. M.M. I diretriz brasileira de prevenção cardiovascular. Arq. Bras. Cardiol. 2014; 102: 420–431. DOI: 10.5935/abc.2013S 012</mixed-citation><mixed-citation xml:lang="en">Simão A. F., Précoma D. B., de Andrade J. P., Filho H. C., Saraiva J. F.K., Oliveira G. M.M. I diretriz brasileira de prevenção cardiovascular. Arq. Bras. Cardiol. 2014; 102: 420–431. DOI: 10.5935/abc.2013S 012</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Cao Z., Jia Y., Zhu B. BNP and NT-proBNP as Diagnostic Biomarkers for Cardiac Dysfunction in Both Clinical and Forensic Medicine. Int J. Mol. Sci. 2019 Apr 12; 20 (8): 1820. DOI: 10.3390/ijms20081820</mixed-citation><mixed-citation xml:lang="en">Cao Z., Jia Y., Zhu B. BNP and NT-proBNP as Diagnostic Biomarkers for Cardiac Dysfunction in Both Clinical and Forensic Medicine. Int J. Mol. Sci. 2019 Apr 12; 20 (8): 1820. DOI: 10.3390/ijms20081820</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Schmitt W., Rühs H., Burghaus R., Diedrich C., Duwal S., Eissing T., Garmann D., Meyer M., Ploeger B., Lippert J. NT-proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure. Clin. Pharmacol. Ther. 2021 Aug; 110 (2): 498–507. DOI: 10.1002/cpt.2222</mixed-citation><mixed-citation xml:lang="en">Schmitt W., Rühs H., Burghaus R., Diedrich C., Duwal S., Eissing T., Garmann D., Meyer M., Ploeger B., Lippert J. NT-proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure. Clin. Pharmacol. Ther. 2021 Aug; 110 (2): 498–507. DOI: 10.1002/cpt.2222</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Fan J., Ma J., Xia N., Sun L., Li B., Liu H. Clinical Value of Combined Detection of CK-MB, MYO, cTnI and Plasma NT-proBNP in Diagnosis of Acute Myocardial Infarction. Clin. Lab. 2017 Mar 1; 63 (3): 427–433. DOI: 10.7754/Clin.Lab.2016.160533</mixed-citation><mixed-citation xml:lang="en">Fan J., Ma J., Xia N., Sun L., Li B., Liu H. Clinical Value of Combined Detection of CK-MB, MYO, cTnI and Plasma NT-proBNP in Diagnosis of Acute Myocardial Infarction. Clin. Lab. 2017 Mar 1; 63 (3): 427–433. DOI: 10.7754/Clin.Lab.2016.160533</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation / Tricco A. C., Lillie E., Zarin W. [et al]. Ann Intern Med. 2018; 169 (7): 467–473. DOI: 10.7326/M18-0850</mixed-citation><mixed-citation xml:lang="en">PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation / Tricco A. C., Lillie E., Zarin W. [et al]. Ann Intern Med. 2018; 169 (7): 467–473. DOI: 10.7326/M18-0850</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Bordbar S., Bigi M. A., Aslani A., Rahimi E., Ahmadi N. Effect of endurance and strength exercise on release of brain natriuretic peptide. J. Cardiovasc Dis Res. 2012 Jan; 3 (1): 22–5. DOI: 10.4103/0975-3583.91599</mixed-citation><mixed-citation xml:lang="en">Bordbar S., Bigi M. A., Aslani A., Rahimi E., Ahmadi N. Effect of endurance and strength exercise on release of brain natriuretic peptide. J. Cardiovasc Dis Res. 2012 Jan; 3 (1): 22–5. DOI: 10.4103/0975-3583.91599</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Cirer-Sastre R., Legaz-Arrese A., Corbi F., George K., Nie J., Carranza-García L.E., Reverter-Masià J. Cardiac Biomarker Release After Exercise in Healthy Children and Adolescents: A Systematic Review and Meta-Analysis. Pediatr. Exerc. Sci. 2019 Feb 1; 31 (1): 28–36. DOI: 10.1123/pes.2018-0058</mixed-citation><mixed-citation xml:lang="en">Cirer-Sastre R., Legaz-Arrese A., Corbi F., George K., Nie J., Carranza-García L.E., Reverter-Masià J. Cardiac Biomarker Release After Exercise in Healthy Children and Adolescents: A Systematic Review and Meta-Analysis. Pediatr. Exerc. Sci. 2019 Feb 1; 31 (1): 28–36. DOI: 10.1123/pes.2018-0058</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Hamasaki H. The Effects of Exercise on Natriuretic Peptides in Individuals without Heart Failure. Sports (Basel). 2016 May 31; 4 (2): 32. DOI: 10.3390/sports4020032</mixed-citation><mixed-citation xml:lang="en">Hamasaki H. The Effects of Exercise on Natriuretic Peptides in Individuals without Heart Failure. Sports (Basel). 2016 May 31; 4 (2): 32. DOI: 10.3390/sports4020032</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Legaz-Arrese A., López-Laval I., George K., Puente-Lanzarote J.J., Mayolas-Pi C., Serrano-Ostáriz E., Revilla-Martí P., Moliner-Urdiales D., Reverter-Masià J. Impact of an endurance training program on exercise-induced cardiac biomarker release. Am. J. Physiol. Heart Circ Physiol. 2015 Apr 15; 308 (8): H913–20. DOI: 10.1152/ajpheart.00914.2014</mixed-citation><mixed-citation xml:lang="en">Legaz-Arrese A., López-Laval I., George K., Puente-Lanzarote J.J., Mayolas-Pi C., Serrano-Ostáriz E., Revilla-Martí P., Moliner-Urdiales D., Reverter-Masià J. Impact of an endurance training program on exercise-induced cardiac biomarker release. Am. J. Physiol. Heart Circ Physiol. 2015 Apr 15; 308 (8): H913–20. DOI: 10.1152/ajpheart.00914.2014</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Mandroukas A., Metaxas T. I., Heller J., Vamvakoudis E., Christoulas K., Riganas C. S., Sendelides T., Stefanidis P., Kotoglou K., Karamouzis I., Mandroukas K. The effect of different exercise-testing protocols on atrial natriuretic peptide. Clin Physiol Funct Imaging. 2011 Jan; 31 (1): 5–10. DOI: 10.1111/j.1475–097X.2010.00971.x</mixed-citation><mixed-citation xml:lang="en">Mandroukas A., Metaxas T. I., Heller J., Vamvakoudis E., Christoulas K., Riganas C. S., Sendelides T., Stefanidis P., Kotoglou K., Karamouzis I., Mandroukas K. The effect of different exercise-testing protocols on atrial natriuretic peptide. Clin Physiol Funct Imaging. 2011 Jan; 31 (1): 5–10. DOI: 10.1111/j.1475–097X.2010.00971.x</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Koretskaya A. Y. Endurance and combined endurance-resistance training in patients with chronic heart failure and preserved ejection fraction. Kuban scientific medical bulletin. 2009; 4 (109): 98–103.</mixed-citation><mixed-citation xml:lang="en">Koretskaya A. Y. Endurance and combined endurance-resistance training in patients with chronic heart failure and preserved ejection fraction. Kuban scientific medical bulletin. 2009; 4 (109): 98–103.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Nilsson B. B., Westheim A., Risberg M. A., Arnesen H., Seljeflot I. No effect of groupbased aerobic interval training on N-terminal pro- B-type natriuretic peptide levels in patients with chronic heart failure. Scand. Cardiovasc. J. 2010 Aug; 44 (4): 223–9. DOI: 10.3109/14017431.2010.496869</mixed-citation><mixed-citation xml:lang="en">Nilsson B. B., Westheim A., Risberg M. A., Arnesen H., Seljeflot I. No effect of groupbased aerobic interval training on N-terminal pro- B-type natriuretic peptide levels in patients with chronic heart failure. Scand. Cardiovasc. J. 2010 Aug; 44 (4): 223–9. DOI: 10.3109/14017431.2010.496869</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Passino C., Severino S., Poletti R., Piepoli M. F., Mammini C., Clerico A., Gabutti A., Nassi G., Emdin M. Aerobic training decreases B-type natriuretic peptide expression and adrenergic activation in patients with heart failure. J. Am. Coll. Cardiol. 2006 May 2; 47 (9): 1835–9. DOI: 10.1016/j.jacc.2005.12.050</mixed-citation><mixed-citation xml:lang="en">Passino C., Severino S., Poletti R., Piepoli M. F., Mammini C., Clerico A., Gabutti A., Nassi G., Emdin M. Aerobic training decreases B-type natriuretic peptide expression and adrenergic activation in patients with heart failure. J. Am. Coll. Cardiol. 2006 May 2; 47 (9): 1835–9. DOI: 10.1016/j.jacc.2005.12.050</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Lara Fernandes J., Serrano C. V., Toledo F., Hunziker M. F., Zamperini A., Teo F. H., Oliveira R. T., Blotta M. H., Rondon M. U., Negrão C. E. Acute and chronic effects of exercise on inflammatory markers and B-type natriuretic peptide in patients with coronary artery disease. Clin. Res Cardiol. 2011 Jan; 100 (1): 77–84. DOI: 10.1007/s00392-010-0215-x</mixed-citation><mixed-citation xml:lang="en">Lara Fernandes J., Serrano C. V., Toledo F., Hunziker M. F., Zamperini A., Teo F. H., Oliveira R. T., Blotta M. H., Rondon M. U., Negrão C. E. Acute and chronic effects of exercise on inflammatory markers and B-type natriuretic peptide in patients with coronary artery disease. Clin. Res Cardiol. 2011 Jan; 100 (1): 77–84. DOI: 10.1007/s00392-010-0215-x</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Badiani S., van Zalen J., Althunayyan A., Al-Borikan S., Treibel T., Marshall A., Patel N., Bhattacharyya S., Lloyd G. Natriuretic peptide release during exercise in patients with valvular heart disease: A systematic review. Int J. Clin. Pract. 2021 Oct; 75 (10): e14137. DOI: 10.1111/ijcp.14137</mixed-citation><mixed-citation xml:lang="en">Badiani S., van Zalen J., Althunayyan A., Al-Borikan S., Treibel T., Marshall A., Patel N., Bhattacharyya S., Lloyd G. Natriuretic peptide release during exercise in patients with valvular heart disease: A systematic review. Int J. Clin. Pract. 2021 Oct; 75 (10): e14137. DOI: 10.1111/ijcp.14137</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Giallauria F., de Lorenzo A., Pilerci F., Manakos A., Lucci R., Psaroudaki M., D’Agostino M., Del Forno D., Vigorito C. Reduction of N terminal-pro-brain (B-type) natriuretic peptide levels with exercise-based cardiac rehabilitation in patients with left ventricular dysfunction after myocardial infarction. Eur. J. Cardiovasc Prev Rehabil. 2006 Aug; 13 (4): 625–32. DOI: 10.1097/01.hjr.0000209810.59831.f4</mixed-citation><mixed-citation xml:lang="en">Giallauria F., de Lorenzo A., Pilerci F., Manakos A., Lucci R., Psaroudaki M., D’Agostino M., Del Forno D., Vigorito C. Reduction of N terminal-pro-brain (B-type) natriuretic peptide levels with exercise-based cardiac rehabilitation in patients with left ventricular dysfunction after myocardial infarction. Eur. J. Cardiovasc Prev Rehabil. 2006 Aug; 13 (4): 625–32. DOI: 10.1097/01.hjr.0000209810.59831.f4</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kutsch J., Faul C., von Scheidt W., Schwaiblmair M., Berghaus T. M. The association of the N-terminal pro-brain-type natriuretic peptide response to exercise with disease severity in therapy-naive pulmonary arterial hypertension: a cohort study. Respir Res. 2018 Jan 15; 19 (1): 8. DOI: 10.1186/s12931-017-0712-9</mixed-citation><mixed-citation xml:lang="en">Kutsch J., Faul C., von Scheidt W., Schwaiblmair M., Berghaus T. M. The association of the N-terminal pro-brain-type natriuretic peptide response to exercise with disease severity in therapy-naive pulmonary arterial hypertension: a cohort study. Respir Res. 2018 Jan 15; 19 (1): 8. DOI: 10.1186/s12931-017-0712-9</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
