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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-16-13-18</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3832</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Фитонутриенты в комплексной диетотерапии алкогольной болезни печени и неалкогольной жировой болезни печени</article-title><trans-title-group xml:lang="en"><trans-title>Phytonutrients in complex diet therapy for alcoholic liver disease and non-alcoholic fatty liver disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4689-3591</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орлова Светлана Владимировна, д. м. н., проф., зав. кафедрой диетологии и клинической нутрициологии, главный научный сотрудник</p><p>Москва</p></bio><bio xml:lang="en"><p>Orlova Svetlana V., DM Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology, Chief Researcher</p><p>Moscow</p></bio><email xlink:type="simple">orlova-sv@rudn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5203-1082</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Водолазкая</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Vodolazkaya</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Водолазкая Ангелина Николаевна, врач-диетолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Vodolazkaya Angelina N., dietitian</p><p>Moscow</p></bio><email xlink:type="simple">drvodolazkaya@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6376-8189</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарасова Ольга Ивановна, к. м. н., доцент, директор центра изучения печени им. проф. П. П. Огурцова, доцент кафедры госпитальная терапия с курсами эндокринологии, гематологии и КЛД</p><p>Москва</p></bio><bio xml:lang="en"><p>Tarasova Olga I. PhD Med, associate professor, director of the Center for the Study of the Liver named after Prof. P. P. Ogurtsov, Associate Professor of Dept of Hospital Therapy with courses in Endocrinology, Hematology and Clinical Diagnostics</p><p>Moscow</p></bio><email xlink:type="simple">tarasova_oi@pfur.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3220-0333</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитина Елена Александровна, к. м. н., доцент кафедры диетологии и клинической нутрициологии, научный сотрудник, эксперт методического аккредитационно-симуляционного центра</p><p>Москва</p></bio><bio xml:lang="en"><p>Nikitina Elena A., PhD Med, associate professor of Dept of Dietetics and Clinical Nutrition1, research fellow, expert of the Methodological Accreditation and Simulation Center</p><p>Moscow</p></bio><email xlink:type="simple">nikitina-ea1@rudn.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3811-9459</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прокопенко</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokopenko</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прокопенко Елена Валерьевна, врач-эндокринолог, диетолог, руководитель отдела развития и сопровождения медицинских информационных системи сервисов</p><p>Москва</p></bio><bio xml:lang="en"><p>Prokopenko Elena V., endocrinologist, dietitian, Project Manager of Medical Dept</p><p>Moscow</p></bio><email xlink:type="simple">elvprokopenko@gmail.com</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0548-3414</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балашова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Balashova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Балашова Наталья Валерьевна, к. б. н., доцент кафедры диетологии и клинической нутрициологии, доцент кафедры клинической лабораторной диагностики факультета усовершенствования врачей</p><p>Москва</p></bio><bio xml:lang="en"><p>Balashova Natalya V., PhD Bio Sci, assistant professor at Dept of Clinical Laboratory Diagnostics of the Faculty of Advanced Training of Doctors3, assistant professor at Dept of Dietetics and Clinical Nutritiology</p><p>Moscow</p><p>Author ID: 832745</p></bio><email xlink:type="simple">BalashovaN77@mail.ru</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-1327-1557</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миносян</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Minosyan</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Миносян Илона Сергеевна, б/з, б/с, врач-гастроэнтеролог центра изучения печени им. проф. П. П. Огурцова КДЦ, аспирант кафедры госпитальная терапия с курсами эндокринологии, гематологии и КЛД</p><p>Москва</p></bio><bio xml:lang="en"><p>Minosyan Ilona S., b/c, b/c, gastroenterologist at the Prof. P. P. Ogurtsov Center for Liver Studies, CDC RUDN University, postgraduate student of Dept of Hospital Therapy with courses in Endocrinology, Hematology and Clinical Diagnostics</p><p>Moscow</p></bio><email xlink:type="simple">1142220093@rudn.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Уразов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Urazov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уразов Виктор Васильевич, директор Института восточной медицины</p><p>Москва</p></bio><bio xml:lang="en"><p>Urazov Victor V., director of the Institute of Oriental Medicine</p><p>Moscow</p></bio><email xlink:type="simple">urazov-vv@rudn.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia n. a. Patrice Lumumba (RUDN University); Scientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of Healt</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М. Ф. Владимирского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research Clinical Institute named after M. F. Vladimirsky</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia n. a. Patrice Lumumba (RUDN University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»;  ФГБУ «Национальный медицинский исследовательский центр терапии и профилактической медицины» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia n. a. Patrice Lumumba (RUDN University); Scientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of Healt; National Medical Research Center for Therapy and Preventive Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ООО «ИНВИТРО»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>“INVITRO” Limited Liability Company</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М. Ф. Владимирского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia n. a. Patrice Lumumba (RUDN University); Moscow Regional Research Clinical Institute named after M. F. Vladimirsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>05</day><month>09</month><year>2024</year></pub-date><volume>0</volume><issue>16</issue><issue-title>Диетология и нутрициология</issue-title><fpage>13</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Орлова С.В., Водолазкая А.Н., Тарасова О.И., Никитина Е.А., Прокопенко Е.В., Балашова Н.В., Миносян И.С., Уразов В.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Орлова С.В., Водолазкая А.Н., Тарасова О.И., Никитина Е.А., Прокопенко Е.В., Балашова Н.В., Миносян И.С., Уразов В.В.</copyright-holder><copyright-holder xml:lang="en">Orlova S.V., Vodolazkaya A.N., Tarasova O.I., Nikitina E.A., Prokopenko E.V., Balashova N.V., Minosyan I.S., Urazov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3832">https://www.med-alphabet.com/jour/article/view/3832</self-uri><abstract><p>Серьезную проблему общественного здравоохранения с разными эпидемиологическими профилями представляют собой как алкогольная болезнь печени (АБП), так и неалкогольная жировая болезнь печени (НАЖБП). Долгосрочной целью лечения хронического гепатоза является предотвращение прогрессирования цирроза и/или рака печени и в итоге продление выживаемости и качество жизни пациентов. Большим потенциалом в оптимизации терапевтического воздействия у таких пациентов обладают фитодобавки, содержащие лекарственные растения, такие как расторопша пятнистая, трифала, имбирь и растения рода Филлантус.</p></abstract><trans-abstract xml:lang="en"><p>Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are serious health problems with different epidemiological profiles. The long-term goal of treating chronic hepatosis is to prevent the progression of cirrhosis and/or liver cancer and prolong survival and patient’s quality of life. Herbal supplements containing medicinal plants, such as milk thistle, triphala, ginger and plants of the genus Phyllanthus, have great potential in optimizing the therapeutic effect in such patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>алкогольная болезнь печени (АБП)</kwd><kwd>неалкогольная жировая болезнь печени (НАЖБП)</kwd><kwd>фитокомплекс</kwd><kwd>расторопша пятнистая</kwd><kwd>трифала</kwd><kwd>имбирь и растения рода Филлантус</kwd></kwd-group><kwd-group xml:lang="en"><kwd>alcoholic liver disease (ALD)</kwd><kwd>non-alcoholic fatty liver disease (NAFLD)</kwd><kwd>phytocomplex</kwd><kwd>Milk Thistle</kwd><kwd>Triphala</kwd><kwd>Ginger and plants of the genus Phyllanthus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jichitu A., Bungau S., Stanescu A. M.A., Vesca C. M., Toma M. M., Bustea C., et al. 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