medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2024-16-8-12medalphabet-3831Research ArticleСтатьиРоль природных антиоксидантов и ингибиторов ферментов в профилактике старения кожиThe role of natural antioxidants and enzyme inhibitors in the prevention of skin aginghttps://orcid.org/0000-0002-4689-3591ОрловаС. В.OrlovaS. V.

Орлова Светлана Владимировна, д. м. н., проф., зав. кафедрой диетологии и клинической нутрициологии, главный научный сотрудник

Москва

Orlova Svetlana V., DM Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology, Chief Researcher

Moscow

orlova-sv@rudn.ruhttps://orcid.org/0000-0002-3811-9459ПрокопенкоЕ. В.ProkopenkoE. V.

Прокопенко Елена Валерьевна, врач-эндокринолог, диетолог, руководитель отдела развития и сопровождения медицинских информационных систем и сервисов

Москва

Prokopenko Elena V., endocrinologist, dietitian

Moscow

elvprokopenko@gmail.comhttps://orcid.org/0000-0003-3220-0333НикитинаЕ. А.NikitinaE. A.

Никитина Елена Александровна, к. м. н., доцент кафедры диетологии и клинической нутрициологии, научный сотрудник, эксперт Методического аккредитационно-симуляционного центра

Москва

Nikitina Elena A., PhD Med, associate professor at Dept of Dietetics and Clinical Nutrition, Research Fellow, Expert of the Methodological Accreditation and Simulation Center

Moscow

nikitina-ea1@rudn.ruhttps://orcid.org/0000-0003-0928-2131БатышеваТ. Т.BatyshevaT. T.

Батышева Татьяна Тимофеевна, д. м. н., проф., заслуженный врач РФ, директор, глав. внештатный детский специалист невролог ДЗМ, глав. внештатный детский специалист по медицинской реабилитации МЗ РФ, зав. кафедрой неврологии, физической, реабилитационной медицины и психологии детского возраста

Москва

Batysheva Tatyana T., DM Sci (habil.), director, head. freelance pediatric specialist neurologist at Dept of Healthcare, head. freelance children’s specialist in medical rehabilitation of the Ministry of Health of the Russian Federation, head of Dept of Neurology, Physical, Rehabilitation Medicine and Childhood Psychology, Honored Doctor of the Russian Federation

Moscow

https://orcid.org/0000-0002-0548-3414БалашоваН. В.BalashovaN. V.

Балашова Наталья Валерьевна, к. б. н., доцент кафедры диетологии и клинической нутрициологии, доцент кафедры клинической лабораторной диагностики факультета усовершенствования врачей

Москва

Author ID: 832745

Balashova Natalya V., PhD Bio Sci, assistant professor at Dept of Clinical Laboratory Diagnostics of the Faculty of Advanced Training of Doctors, assistant professor at Dept of Dietetics and Clinical Nutritiology

Moscow

Author ID: 832745

BalashovaN77@mail.ruhttps://orcid.org/0000-0001-8448-8493АлексееваМ. В.AlekseevaM. V.

Алексеева Марина Валерьевна, к. м. н., зам. директора по организационно-методической работе

Москва

Alekseeva Marina.V., PhD Med, deputy director for Organizational and Methodological Work

Moscow

https://orcid.org/0000-0002-5203-1082ВодолазкаяА. Н.VodolazkayaA. N.

Водолазкая Ангелина Николаевна, врач-диетолог

Vodolazkaya Angelina N., dietitian

ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»РоссияPeoples’ Friendship University of Russia» named after Patrice Lumumba (RUDN University); Scientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of Health, Russia Moscow Regional Research Clinical Institute named after M. F. VladimirskyRussian FederationООО «ИНВИТРО»Россия“INVITRO” LLCRussian FederationФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»; ФГБУ «Национальный медицинский исследовательский центр терапии и профилактической медицины» Минздрава РоссииРоссияPeoples’ Friendship University of Russia» named after Patrice Lumumba (RUDN University); Scientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of Health, Russia Moscow Regional Research Clinical Institute named after M. F. Vladimirsky; National Medical Research Center for Therapy and Preventive MedicineRussian FederationФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы» (РУДН); ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М. Ф. Владимирского»РоссияPeoples’ Friendship University of Russia» named after Patrice Lumumba (RUDN University); National Medical Research Center for Therapy and Preventive MedicineRussian FederationГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»РоссияPeoples’ Friendship University of Russia» named after Patrice Lumumba (RUDN University); Scientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of HealthRussian Federation202404092024016Диетология и нутрициология812Copyright © Орлова С.В., Прокопенко Е.В., Никитина Е.А., Батышева Т.Т., Балашова Н.В., Алексеева М.В., Водолазкая А.Н., 20242024Орлова С.В., Прокопенко Е.В., Никитина Е.А., Батышева Т.Т., Балашова Н.В., Алексеева М.В., Водолазкая А.Н.Orlova S.V., Prokopenko E.V., Nikitina E.A., Batysheva T.T., Balashova N.V., Alekseeva M.V., Vodolazkaya A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/3831

Старение – это прогрессирующее дегенеративное состояние, сопровождающееся нарастающей потерей физиологической целостности и функции. Старение является неизбежным процессом, который, в частности, включает в себя дисбаланс между антиоксидантной защитой и активными формами кислорода, изменениями в обновлении белков и митохондрий, истощением теломер, клеточным старением, эпигенетическими изменениями и истощением стволовых клеток. Эти состояния связаны с легким и умеренным воспалением, которое всегда сопровождает процесс старения и возрастные заболевания. Старение кожи – это очень сложное биологическое явление, контролируемое многими внутренними и внешними факторами. Природные вещества являются предпочтительными для улучшения здоровья и внешнего вида кожи.

Aging is a progressive degenerative condition accompanied by an increasing loss of physiological integrity and function. Aging is an inevitable process that includes, among other things, an imbalance between antioxidant defenses and reactive oxygen species, changes in protein and mitochondrial turnover, telomere attrition, cellular senescence, epigenetic changes and stem cell depletion. These conditions are associated with mild to moderate inflammation, which always accompanies the aging process and age-related diseases. Skin aging is a very complex biological phenomenon controlled by many internal and external factors. Natural substances are preferred to improve the health and appearance of the skin.

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The authors declare that there are no conflicts of interest present.