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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-9-87-90</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3783</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Эффективность и безопасность нитевой имплантологии в отдаленный период времени: данные патоморфологического исследования</article-title><trans-title-group xml:lang="en"><trans-title>Efficiency and safety of thread implantology in the long term: data from a pathomorphological study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-1302-1467</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Серов</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Serov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Серов Дмитрий Николаевич - к. м. н., гл. врач.</p><p>г. Химки</p></bio><bio xml:lang="en"><p>Dmitry N. Serov - PhD Med, chief physician.</p><p>Khimki</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3190-7460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Круглова</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruglova</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Круглова Мария Сергеевна - студентка 3 курса лечебного факультета.</p><p>Москва</p></bio><bio xml:lang="en"><p>Maria S. Kruglova - 3rd year student of the Faculty of Medicine.</p><p>Moscow</p></bio><email xlink:type="simple">kruglovamashulka@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центр медицинской косметологии ООО «Эстетика Групп»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Centre for Medical Cosmetology of ‘Aesthetics Group’ Co.</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>21</day><month>07</month><year>2024</year></pub-date><volume>0</volume><issue>9</issue><issue-title>Дерматология (1)</issue-title><fpage>87</fpage><lpage>90</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Серов Д.Н., Круглова М.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Серов Д.Н., Круглова М.С.</copyright-holder><copyright-holder xml:lang="en">Serov D.N., Kruglova M.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3783">https://www.med-alphabet.com/jour/article/view/3783</self-uri><abstract><p>Эволюция методов, используемых в эстетической медицине, включает переход к менее инвазивным процедурам, обладающим высокой безопасностью и минимальным периодом реабилитации. Именно поэтому многочисленные неинвазивные методы коррекции инволютивных изменений кожи лица (нитевой лифтинг, аппаратные методики) изучаются на предмет эффективности и безопасности в течение последних десятилетий. Такие методики позволяют улучшить результаты лечения и избежать или отложить по времени проведение хирургического вмешательства.</p><sec><title>Материал и методы</title><p>Материал и методы. В работе проводилось патоморфологическое изучение материала, взятого при помощи биопсии в местах имплантирования нитей и окружающих тканях (отступ 1 см) (Nano spring, Exellence Visage, Exellence Visage HA) в сроки 12 месяцев после проведения нитевого лифтинга. Из готовых парафиновых блоков изготавливали парафиновые срезы толщиной 5–7 мкм окрашивали: гематоксилином – эозином; по методу Вейгерта-Ван Гизона; окраска Sirius Red. Используя микроскоп с цифровой фото насадкой Sony, разрешением 12 мегапикселей из каждого гистологического препарата было получено по пять фотографий.</p></sec><sec><title>Результаты исследования</title><p>Результаты исследования. В результате патоморфологического исследования лоскута кожи и подкожно-жировой клетчатки с синтетической нитью в жировой ткани было выявлено, что по периферии, изучаемого материала отмечается умеренное хроническое воспаление (гигантские клетки по типу клеток инородных тел, лимфоциты, фибробласты) и слабый фиброз, а также преобладание коллагена I типа в коже, а подкожной жировой клетчатке преобладал коллаген III типа.</p></sec></abstract><trans-abstract xml:lang="en"><p>The evolution of methods used in aesthetic medicine includes a transition to less invasive procedures with high safety and minimal recovery time. That is why numerous non-invasive methods for correcting involutive changes in facial skin (thread lifting, hardware techniques) have been studied for effectiveness and safety over the past decades. Such techniques can improve treatment results and avoid or delay surgical intervention.</p><sec><title>Material and methods</title><p>Material and methods. The work involved a pathomorphological study of material taken by biopsy at the sites of thread implantation and surrounding tissues (1 cm indentation) (Nano spring, Excellence Visage, Excellence Visage HA) within 12 months after thread lifting. Paraffin sections with a thickness of 5–7 microns were made from ready-made paraffin blocks and stained with: hematoxylin – eosin; according to the Weigert-Van Gieson method; Sirius Red paint. Using a microscope with a Sony digital photo attachment with a resolution of 12 megapixels, five photographs were taken from each histological specimen.</p></sec><sec><title>Research results</title><p>Research results. As a result of a pathomorphological study of a flap of skin and subcutaneous fat with a synthetic thread in the adipose tissue, it was revealed that along the periphery of the studied material there was moderate chronic inflammation (giant cells of the type of foreign body cells, lymphocytes, fibroblasts) and weak fibrosis, as well as a predominance type I collagen in the skin, and type III collagen predominated in subcutaneous fat tissue.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>имплантированные нити</kwd><kwd>гистологическое исследование</kwd><kwd>коллагеновые волокна</kwd><kwd>эластические волокна</kwd><kwd>отдаленные результаты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>implanted threads</kwd><kwd>histological examination</kwd><kwd>collagen fibers</kwd><kwd>elastic fibers</kwd><kwd>long-term results</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Yoo K. H., Kim W. S., Hong K. K., Kim B. J. Chronic inflammatory reaction after thread lifting: a delayed, unusual complication of non-absorbable thread. Dermatol Surg. 2015 April; 41 (4): 510–3.</mixed-citation><mixed-citation xml:lang="en">Yoo K. H., Kim W. S., Hong K. K., Kim B. J. Chronic inflammatory reaction after thread lifting: a delayed, unusual complication of non-absorbable thread. Dermatol Surg. 2015 April; 41 (4): 510–3.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Sarygul Guduk S., Karadzha N. Safety and complications of absorbable poly-L-lactic acid and polylactide/glycolide sutures: an experience in 148 consecutive patients. J Cosmet Dermatol. 2018 Dec; 17 (6): 1189–1193.</mixed-citation><mixed-citation xml:lang="en">Sarygul Guduk S., Karadzha N. Safety and complications of absorbable poly-L-lactic acid and polylactide/glycolide sutures: an experience in 148 consecutive patients. J Cosmet Dermatol. 2018 Dec; 17 (6): 1189–1193.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Wu W. T. Serrated sutures for facial rejuvenation. Aesthete Surg J. 2008; 28 (3): 335–47. 582–7.</mixed-citation><mixed-citation xml:lang="en">Wu W. T. Serrated sutures for facial rejuvenation. Aesthete Surg J. 2008; 28 (3): 335–47. 582–7.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Rachel J. D., Luck E. B., Larson B. Rates of complications and early recurrence in 29 patients after facial rejuvenation with a barbed suture lift. Dermatol Surg 2010; 36: 348–54.</mixed-citation><mixed-citation xml:lang="en">Rachel J. D., Luck E. B., Larson B. Rates of complications and early recurrence in 29 patients after facial rejuvenation with a barbed suture lift. Dermatol Surg 2010; 36: 348–54.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Lee C. J., Park J. G., Yoo S. G., Hwang J. G. et al. Dysesthesia and fasciculation: Unusual complications after face lift with barbed sutures. Dermatol Surg 2007; 33: 253–5.</mixed-citation><mixed-citation xml:lang="en">Lee C. J., Park J. G., Yoo S. G., Hwang J. G. et al. Dysesthesia and fasciculation: Unusual complications after face lift with barbed sutures. Dermatol Surg 2007; 33: 253–5.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Суламанидзе М., Суламанидзе Г., Воздвиженский И., Суламанидзе С. Избегание осложнений при наложении швов «Аптос». «Эстет Сург Дж.» 2011; 31: 863–73.</mixed-citation><mixed-citation xml:lang="en">Sulamanidze M., Sulamanidze G., Vozdvizhensky I., Sulamanidze S. Avoiding complications when applying Aptos sutures. «Aesthete Surg J.» 2011; 31: 863–73 (In Russ).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
