medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2024-13-34-41medalphabet-3718Research ArticleСтатьиОтдаленные последствия лучевой терапии в поликлинической практикеLong-term effects of radiation therapy in outpatient practicehttps://orcid.org/0000-0001-8124-109XКарселадзеН. Д.KarseladzeN. D.

Карселадзе Наталья Джимшеровна - к. м. н., врач-терапевт.

Москва

Karseladze Natalia D. - PhD Med, general practitioner.

Moscow

karseladze@yandex.ruhttps://orcid.org/0000-0002-7833-935XТигановаО. А.TiganovaO. A.

Тиганова Ольга Александровна - к. м. н., доцент кафедры госпитальной педиатрии педиатрического факультета РНИМУ имени Н. И. Пирогова, врач детский онколог-гематолог Морозовская ДКБ ДЗ города Москвы.

Москва

Tiganova Olga A. - PhD Med, associate professor, staff of the State Academy of Pediatrics Pirogov RNRMU, pediatric oncologist-hematologist Morozovskaya Children`s CC H of the Department of Health of the City of Moscow.

Moscow

svudy@yandex.ruhttps://orcid.org/0000-0001-8375-4569ИльенкоЛ. И.IlyenkoL. I.

Ильенко Лидия Ивановна - д. м. н., проф., декан педиатрического факультета, заведующая кафедрой госпитальной педиатрии № 2 педиатрического факультета.

Москва

Ilyenko Lydia I. - DM Sci (habil.), professor, dean of the Faculty of Pediatrics, head of the Dept of Hospital Pediatrics No. 2 of the Faculty of Pediatric.

Moscow

vrach315@yandex.ruhttps://orcid.org/0000-0002-4293-3285ОрловаН. В.OrlovaN. V.

Орлова Наталья Васильевна - д. м. н., проф., проф. кафедры факультетской терапии педиатрического факультета.

Москва

Orlova Natalia V. - DM Sci (habil.), professor at the Dept of faculty therapy.

Moscow

vrach315@yandex.ruhttps://orcid.org/0000-0002-8594-6406ДанелянС. Ж.DanelyanS. Z.

Данелян Соня Жоровна, к. м. н., заместитель главного врача по акушерскогинекологической помощи.

Москва

Danelyan Sonya Zh. - PhD Med, deputy chief physician for Obstetric and Gynecological Care.

Moscow

vrach315@yandex.ruМедицинский центр аэропорта Московского авиационного узлаРоссияMedical Center of the Airport of the MOWRussian FederationФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Минздрава России; ГБУЗ «Морозовская детская городская клиническая больница Департамента здравоохранения города Москвы»РоссияPirogov Russian National Research Medical University, Ministry of Healthcare of Russia; Morozovskaya Children`s City Clinical Hospital of the Department of Health of the City of MoscowRussian FederationФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Минздрава РоссииРоссияPirogov Russian National Research Medical University, Ministry of Healthcare of RussiaRussian FederationГБУЗ «Московский многопрофильный клинический центр „Коммунарка“ ДЗМ»РоссияMoscow multidisciplinary clinical center «Kommunarka»Russian Federation202413052024013«Современная поликлиника» (1)3441Copyright © Карселадзе Н.Д., Тиганова О.А., Ильенко Л.И., Орлова Н.В., Данелян С.Ж., 20242024Карселадзе Н.Д., Тиганова О.А., Ильенко Л.И., Орлова Н.В., Данелян С.Ж.Karseladze N.D., Tiganova O.A., Ilyenko L.I., Orlova N.V., Danelyan S.Z.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/3718

Лучевая терапия является одним из основных методов лечения злокачественных новообразований. Наряду с высокой эффективностью лучевая терапия приводит к осложнениям в раннем и позднем периоде. Врачи общей практики и терапевты в недостаточной мере знакомы с отдаленными радиационно-индуцированными осложнениями. В статье представлены данные о патогенезе, клинических проявлениях, диагностике и лечении лучевых поражений костной системы, легких, миокарда, желудочно-кишечного тракта, мочеполовой системы, системы кроветворения, а также о хроническом болевом синдроме. Симптомы поздних осложнений лучевой терапии неспецифичны и сходны с симптомами соматических заболеваний. Знание клинических проявлений радиационно-индуцированных осложнений в отдаленном периоде позволяет своевременно провести диагностику и лечение.

Moscow multidisciplinary clinical center «Kommunarka», Moscow, Russia SUMMARY Radiation therapy is one of the main methods of treating malignant neoplasms. Along with high efficiency, radiation therapy leads to complications in the early and late period. General practitioners and therapists are insufficiently familiar with long-term radiation-induced complications. The article presents data on the pathogenesis, clinical manifestations, diagnosis and treatment of radiation lesions of the bone system, lungs, myocardium, gastrointestinal tract, genitourinary system, hematopoiesis system, as well as chronic pain syndrome. The symptoms of late complications of radiation therapy are nonspecific and similar to the symptoms of somatic diseases. Knowledge of the clinical manifestations of radiation-induced complications in the long term allows timely diagnosis and treatment.

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The authors declare that there are no conflicts of interest present.