<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-11-77-80</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3709</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Комплексная оценка эффективности диагностики и лечения пациентов с хроническим апикальным периодонтитом на основании микробиологического и джоульметрического методов исследования</article-title><trans-title-group xml:lang="en"><trans-title>Comprehensive assessment of the effectiveness of diagnosis and treatment of patients with chronic apical periodontitis based on microbiological and joulemetric research methods</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5097-0601</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фролова</surname><given-names>К. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Frolova</surname><given-names>K. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кристина Евгеньевна Фролова - старший преподаватель кафедры стоматологии.</p><p>Пенза</p></bio><bio xml:lang="en"><p>Kristina Evgenievna Frolova -  Senior lecturer of the Department of Dentistry.</p></bio><email xlink:type="simple">kristina.frolova.1983@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2938-3063</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зюлькина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zyulkina</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лариса Алексеевна Зюлькина - д.м.н., доцент, заведующий кафедрой стоматологии.</p><p>Пенза</p></bio><bio xml:lang="en"><p>Larisa Alekseevna Zyulkina - Doctor of medical sciences, associate professor, head of the Department of Dentistry.</p></bio><email xlink:type="simple">larisastom@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1746-5878</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юркевич</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yurkevich</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Владимирович Юркевич - д.м.н., доцент, член-корреспондент РАЕН, декан стоматологического факультета, заведующий кафедрой стоматологии ортопедической.</p><p>Хабаровск</p></bio><bio xml:lang="en"><p>Alexander Vladimirovich Yurkevich - Doctor of Medical Sciences, Associate Professor, Corresponding Member of the Russian Academy of Natural Sciences, Dean of the Faculty of Dentistry, Head of the Department of Orthopedic Dentistry of the Far Eastern State Medical University of the Ministry of Health of Russia.</p></bio><email xlink:type="simple">dokdent@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5678-1104</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефремова Анастасия Владимировна - к.м.н., доцент кафедры стоматологии дицинского института.</p><p>Пенза</p></bio><bio xml:lang="en"><p>Anastasia Vladimirovna Efremova - Candidate of medical sciences, associate professor.</p></bio><email xlink:type="simple">nastasya.efremova.87@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Пензенский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО Дальневосточный государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far Eastern State Medical University of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>12</day><month>05</month><year>2024</year></pub-date><volume>0</volume><issue>11</issue><issue-title>Стоматология (2)</issue-title><fpage>77</fpage><lpage>80</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фролова К.Е., Зюлькина Л.А., Юркевич А.В., Ефремова А.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Фролова К.Е., Зюлькина Л.А., Юркевич А.В., Ефремова А.В.</copyright-holder><copyright-holder xml:lang="en">Frolova K.E., Zyulkina L.A., Yurkevich A.V., Efremova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3709">https://www.med-alphabet.com/jour/article/view/3709</self-uri><abstract><sec><title>Актуальность и цели</title><p>Актуальность и цели. Увеличение числа пациентов с хроническим апикальным периодонтитом становится общемировой тенденцией, что опосредовано несколькими факторами: формированием очагов хронического инфицирования, увеличением количества различных одонтогенных осложнений, приводящих к потере причинного зуба, снижение общей резистентности и развитию стойкой сенсибилизации организма</p><p>Цель исследования – оценка эффективности диагностических мероприятий на основе комплекса микробиологических и джоульметрических методов у пациентов с хроническим апикальным периодонтитом.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Обследованы 25 пациентов с установленным диагнозом «хронический апикальный периодонтит». Проведены микробиологический и джоульметрический анализы системы корневых каналов до и на этапах лечения с применением метода отсроченной обтурации, предусматривающей внутриканальное введение препарата высокодисперсной гидроокиси кальция.</p></sec><sec><title>Результаты</title><p>Результаты. Проведенный комплексный анализ результатов бактериологического и джоульметрического исследований содержимого системы корневых каналов у обследуемых пациентов на диагностическом этапе и этапах лечения полностью соответствовали клинической картине течения данной нозологической формы и отражали динамику (отрицательную и положительную) воспалительного процесса в исследуемой периапикальной области.</p></sec><sec><title>Выводы</title><p>Выводы. Сочетанное применение микробиологических и джоульметрических методик увеличивает эффективность лечебно-диагностических мероприятий у пациентов с хроническим апикальным периодонтитом, что в свою очередь снижает риск возможных осложнений и способствует повышению эффективности непосредственных и отдаленных результатов терапии.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. An increase in the number of patients with chronic apical periodontitis is becoming a global trend, which is mediated by several factors: the formation of foci of chronic infection, an increase in the number of various odontogenic complications leading to the loss of a causal tooth, a decrease in general resistance and the development of persistent sensitization of the body.</p><p>The aim of the study was to evaluate the effectiveness of diagnostic measures based on a complex of microbiological and joulemetric methods in patients with chronic apical periodontitis.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 25 patients with the established diagnosis of «chronic apical periodontitis» were examined. Microbiological and joulemetric analyses of the root canal system were performed before and at the stages of treatment using the delayed obturation method, which provides for intra-channel administration of a preparation of highly dispersed calcium hydroxide.</p></sec><sec><title>Results</title><p>Results. The comprehensive analysis of the results of bacteriological and joulemetric studies of the contents of the root canal system in the examined patients at the diagnostic and treatment stages fully corresponded to the clinical picture of the course of this nosological form and reflected the dynamics (negative and positive) of the inflammatory process in the studied periapical region.</p></sec><sec><title>Conclusions</title><p>Conclusions. The combined use of microbiological and joulemetric techniques increases the effectiveness of therapeutic and diagnostic measures in patients with chronic apical periodontitis, which in turn reduces the risk of possible complications and improves the effectiveness of immediate and long-term therapy results.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический апикальный периодонтит</kwd><kwd>джоульметрический метод</kwd><kwd>микробиологический метод</kwd><kwd>высокодисперсная гидроокись кальция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic apical periodontitis</kwd><kwd>joulemetric method</kwd><kwd>microbiological method</kwd><kwd>highly dispersed calcium hydroxide</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ekert T., Krois J., Meinhold L., Elhennawy K., Emara R., Golla T., Schwendicke F. Deep Learning for the Radiographic Detection of Apical Lesions// J Endod. 2019. Vol. 45, № 7. P. 917-922. DOI: 10.1016/j.joen.2019.03.016.</mixed-citation><mixed-citation xml:lang="en">Ekert T., Krois J., Meinhold L., Elhennawy K., Emara R., Golla T., Schwendicke F. Deep Learning for the Radiographic Detection of Apical Lesions// J Endod. 2019. Vol. 45, № 7. P. 917-922. DOI: 10.1016/j.joen.2019.03.016.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Patel, S.; Durack, C. Radiology of Apical Periodontitis. Essent. Endodontology// Prev. Treat. Apical.Periodontitis 2019. P. 179–210.</mixed-citation><mixed-citation xml:lang="en">Patel, S.; Durack, C. Radiology of Apical Periodontitis. Essent. Endodontology// Prev. Treat. Apical.Periodontitis 2019. P. 179–210.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kanagasingam S.; Hussaini H.M.; Soo I.; Baharin S.; Ashar, A.; Patel S. Accuracy of Single and Parallax Film and Digital Periapical Radiographs in Diagnosing Apical Periodontitis – A Cadaver Study.Int. // Endod. J.2017. P. 427–436. DOI: 10.1111/iej.12651.</mixed-citation><mixed-citation xml:lang="en">Kanagasingam S.; Hussaini H.M.; Soo I.; Baharin S.; Ashar, A.; Patel S. Accuracy of Single and Parallax Film and Digital Periapical Radiographs in Diagnosing Apical Periodontitis – A Cadaver Study.Int. // Endod. J.2017. P. 427–436. DOI: 10.1111/iej.12651.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kruse C., Spin-Neto R., Reibel J., Wenzel A., Kirkevang L.L. Diagnostic validity of periapical radiography and CBCT for assessing periapical lesions that persist after endodontic surgery. Dentomaxillofac Radiol. // Kaohsiung Book of Abstracts. 2017. P. 1–3. DOI: 10.1259/dmfr.20170210.</mixed-citation><mixed-citation xml:lang="en">Kruse C., Spin-Neto R., Reibel J., Wenzel A., Kirkevang L.L. Diagnostic validity of periapical radiography and CBCT for assessing periapical lesions that persist after endodontic surgery. Dentomaxillofac Radiol. // Kaohsiung Book of Abstracts. 2017. P. 1–3. DOI: 10.1259/dmfr.20170210.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Li C.W., Lin S.Y., Chou H.S., Chen T.Y., Chen Y.A., Liu S.Y., Liu, Y.L., Chen C.A., Huang Y.C., Chen S.L. et al. Detection of Dental Apical Lesions Using CNNs on Periapical Radiograph. //Sensors (Basel) 2021. P. 1–17. DOI: 10.3390/s21217049.</mixed-citation><mixed-citation xml:lang="en">Li C.W., Lin S.Y., Chou H.S., Chen T.Y., Chen Y.A., Liu S.Y., Liu, Y.L., Chen C.A., Huang Y.C., Chen S.L. et al. Detection of Dental Apical Lesions Using CNNs on Periapical Radiograph. //Sensors (Basel) 2021. P. 1–17. DOI: 10.3390/s21217049.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Ba-Hattab, R., Barhom N., Osman S.A.A., Naceur I., Odeh A., Asad A., Al-Najdi, S.A.R.N., Ameri E., Daer A., Silva R.L.B.D. et al. Detection of Periapical Lesions on Panoramic Radiographs Using Deep Learning. // Appl. Sci. 2023. P. 1–12.</mixed-citation><mixed-citation xml:lang="en">Ba-Hattab, R., Barhom N., Osman S.A.A., Naceur I., Odeh A., Asad A., Al-Najdi, S.A.R.N., Ameri E., Daer A., Silva R.L.B.D. et al. Detection of Periapical Lesions on Panoramic Radiographs Using Deep Learning. // Appl. Sci. 2023. P. 1–12.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hilmi A., Patel S., Mirza K., Galicia J.C. Efficacy of imaging techniques for the diagnosis of apical periodontitis: A systematic review. // Int Endod J. 2023. Vol. 56. № 3. P. 326–339. DOI: 10.1111/iej.13921.</mixed-citation><mixed-citation xml:lang="en">Hilmi A., Patel S., Mirza K., Galicia J.C. Efficacy of imaging techniques for the diagnosis of apical periodontitis: A systematic review. // Int Endod J. 2023. Vol. 56. № 3. P. 326–339. DOI: 10.1111/iej.13921.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Патент № 2798671 C1 Российская Федерация, МПК A61B 5/00, G01N 33/00, G01N 27/66. Способ экспресс-диагностики воспаления тканей периодонта № 2022128944: заявл. 08.11.2022: опубл. 23.06.2023 / К.Е. Фролова, Л.А. Зюлькина, С.М. Геращенко, А.В. Демидов; заявитель Федеральное государственное бюджетное образовательное учреждение высшего образования «Пензенский государственный университет».</mixed-citation><mixed-citation xml:lang="en">Patent No. 2798671 C1 Russian Federation, IPC A61B 5/00, G01N 33/00, G01N 27/66. Method of rapid diagnosis of periodontal tissue inflammation No. 2022128944 : application 08.11.2022 : publ. 23.06.2023 / K.E. Frolova, L.A. Zyulkina, S.M. Gerashchenko, A.V. Demidov; applicant Federal State Budgetary Educational Institution of Higher Education «Penza State University» (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Рентгенологическая оценка эффективности лечения хронического апикального периодонтита препаратами на основе высокодисперсной гидроокиси кальция / К.Е. Фролова, Л.А. Зюлькина, С.М. Геращенко [и др.] // Медицинский вестник Башкортостана. – 2023. – Т. 18, № 3(105). – С. 25–28.</mixed-citation><mixed-citation xml:lang="en">Frolova K.E., Zyulkina L.A., Gerashchenko S.M. et al. X-ray evaluation of the effectiveness of treatment of chronic apical periodontitis with drugs based on highly dispersed calcium hydroxide // Medical Bulletin of Bashkortostan. 2023. Vol. 18, № 3(105): 25–28 (In Russ.)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
