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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-5-43-47</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3649</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Клинический случай нетипичной клинической картины почечной колики у невербальной пациентки</article-title><trans-title-group xml:lang="en"><trans-title>A clinical case of an atypical clinical pattern of renal colic in a nonverbal patient</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-8893-7938</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Францев</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Frantsev</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Францев Роман Сергеевич - доцент кафедры урологии СГМУ, врач-уролог ГКБСМП.</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Frantsev Roman S. - associate professor at Dept of Urology, Urologist.</p><p>Stavropol</p></bio><email xlink:type="simple">francuz26@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1659-319X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Деревянко</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Derevyanko</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Деревянко Татьяна Игоревна - д.м.н., профессор, заведующий кафедрой урологии и детской урологии-андрологии.</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Derevyanko Tatyana I. - DM Sci (habil.), professor, head of Dept of Urology and Paediatric Urology-Andrology.</p><p>Stavropol</p></bio><email xlink:type="simple">uro-dep@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павленко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlenko</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павленко Игорь Владимирович - к.м.н., врач-уролог, зав. урологическим отделением.</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Pavlenko Igor V. - PhD Med, urologist, head of Urology Dept.</p><p>Stavropol</p></bio><email xlink:type="simple">igorpavlenko1974@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хаджиев</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Hadzhiev</surname><given-names>O. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хаджиев Одиссей Гераклитович - врач-уролог урологического отделения № 1.</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Khadzhiev Odisey G. - urologist, Urological Dept No.1.</p><p>Stavropol</p></bio><email xlink:type="simple">odissey15ru@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-1226-373X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Osipov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Осипов Арсен Валерьевич - врач-уролог.</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Osipov Arsen V. - urologist.</p><p>Stavropol</p></bio><email xlink:type="simple">475888@ro.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6891-0332</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карасева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Karaseva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карасева Наталья Владимировна - старший преподаватель кафедры биологии и общей генетики.</p><p>Москва</p></bio><bio xml:lang="en"><p>Karaseva Natalya V. - senior lecturer at Dept of Biology and General Genetics.</p><p>Moscow</p></bio><email xlink:type="simple">karaseva-nv@rudn.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-7961-6612</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крупина</surname><given-names>О. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Krupina</surname><given-names>O. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крупина Ольга Олеговна - студентка 2 курса лечебного факультета.</p><p>Москва</p></bio><bio xml:lang="en"><p>Krupina Olga O. - 2nd year student at General Medicine Faculty of Medical Institute.</p><p>Moscow</p></bio><email xlink:type="simple">1132226404@rudn.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткаченко</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkachenko</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ткаченко Даниил Михайлович - студент 6 курса лечебного факультета.</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Tkachenko Daniil M. - 6th year student at General Medicine Faculty.</p><p>Moscow</p></bio><email xlink:type="simple">kd1800@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ставропольский государственный медицинский университет» Минздрава России; ГБУЗ СК «Городская клиническая больница скорой медицинской помощи»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University; City Clinical Emergency Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ставропольский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ СК «Городская клиническая больница скорой медицинской помощи»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Emergency Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Ставропольский краевой клинический консультативно-диагностический центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol Regional Clinical Consulting and Diagnostic Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов им. Патриса Лумумбы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia n.a. Patrice Lumumba</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>07</day><month>05</month><year>2024</year></pub-date><volume>0</volume><issue>5</issue><issue-title>Практическая гастроэнтерология (1)</issue-title><fpage>43</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Францев Р.С., Деревянко Т.И., Павленко И.В., Хаджиев О.Г., Осипов А.В., Карасева Н.В., Крупина О.О., Ткаченко Д.М., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Францев Р.С., Деревянко Т.И., Павленко И.В., Хаджиев О.Г., Осипов А.В., Карасева Н.В., Крупина О.О., Ткаченко Д.М.</copyright-holder><copyright-holder xml:lang="en">Frantsev R.S., Derevyanko T.I., Pavlenko I.V., Hadzhiev O.G., Osipov A.V., Karaseva N.V., Krupina O.O., Tkachenko D.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3649">https://www.med-alphabet.com/jour/article/view/3649</self-uri><abstract><p>Почечная колика – это состояние, вызванное прохождением конкремента из почки через мочеточник в мочевой пузырь, которое сопровождается выраженным болевым синдромом. Пациенты с почечной коликой часто обращаются за неотложной помощью с жалобами на сильную боль, тошноту, дизурию. Однако, существует категория людей, которые по разным причинам не могут словесно выразить свои ощущения. Такие пациенты называются невербальными. Невербальные пациенты – люди с тяжелыми когнитивными нарушениями или те, кто временно не может говорить из-за операции или болезни, но они все еще могут демонстрировать боль с помощью невербальных сигналов. В этой статье мы представляем наблюдение за нетипичной клинической картиной почечной колики у невербальной пациентки пожилого возраста. У наблюдаемой женщины острый приступ почечной колики длился 5 дней проходил сначала под «маской» острого панкреатита. Не получая патогенетическую терапию у больной, развился острый обструктивный пиелонефрит, септический шок, который изначально был принят за острое нарушение мозгового кровообращения. Выполненная компьютерная томография (КТ) помогла выявить конкремент в верхней трети мочеточника слева, нарушение оттока мочи из левой почки. Пациентке в экстренном порядке был установлен стент в лоханку левой почки, восстановлен отток мочи, назначена противовоспалительная дезинтоксикационнная литолитическая терапия. После чего состояние пациентки значительно улучшилось, а через 3 месяца при контрольной КТ было замечено уменьшение размеров и фрагментация конкремента.</p><p>Заключение. Невербальные пациенты представляют собой особую группу пациентов, клиническая картина которых может протекать смазано, или атипично. Оценка симптомов боли у невербальных пациентов затруднена, что может привести к постановке неверного диагноза и удлинить срок диагностики заболевания. Так же на своевременность диагностики почечной колики у невербальных пациентов влияет локализация боли, так как ее иррадиирующий характер может направить диагностический поиск «по ложному следу».</p></abstract><trans-abstract xml:lang="en"><p>Renal colic is a condition caused by the passage of a concretion from the kidney through the ureter into the bladder, which is accompanied by a pronounced pain syndrome. Patients with renal colic often seek emergency help with complaints of severe pain, nausea, dysuria. However, there is a category of people who, for various reasons, cannot verbally express their feelings. Such patients are called nonverbal. Nonverbal patients are people with severe cognitive impairments or those who are temporarily unable to speak due to surgery or illness, but they can still demonstrate pain using nonverbal signals.In this article, we present an observation of an atypical clinical picture of renal colic in a nonverbal elderly patient. In the observed woman, an acute attack of renal colic lasted 5 days and passed first under the «mask» of acute pancreatitis. Without receiving pathogenetic therapy, the patient developed acute obstructive pyelonephritis, septic shock, which was initially mistaken for an acute violation of cerebral circulation. The performed computed tomography (CT) helped to identify a concretion in the upper third of the ureter on the left, a violation of the outflow of urine from the left kidney. The patient urgently had a stent installed in the pelvis of the left kidney, urine outflow was restored, anti-inflammatory, detoxification, litolytic therapy was prescribed. After that, the patient's condition improved significantly, and after 3 months, a decrease in the size and fragmentation of the concretion was observed during the control CT scan.</p><p>Conclusion. Nonverbal patients are a special group of patients whose clinical picture may be blurred or atypical. Assessment of pain symptoms in nonverbal patients is difficult, which can lead to an incorrect diagnosis and lengthen the period of diagnosis of the disease. The timely diagnosis of renal colic in nonverbal patients is also affected by the localization of pain, since its irradiating nature can direct the diagnostic search «on the wrong track».</p></trans-abstract><kwd-group xml:lang="ru"><kwd>почечная колика</kwd><kwd>МКБ</kwd><kwd>невербальный пациент</kwd><kwd>боль</kwd><kwd>компьютерная томография (КТ)</kwd><kwd>атипичная клиническая картина</kwd><kwd>обструктивный пиелонефрит</kwd><kwd>септический шок (Septic Shock)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>renal colic</kwd><kwd>urolithiasis</kwd><kwd>nonverbal patient</kwd><kwd>pain</kwd><kwd>computed tomography (CT)</kwd><kwd>atypical clinical picture</kwd><kwd>obstructive pyelonephritis</kwd><kwd>Septic Shock</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Alfahhad MF, Qasem HA, Alrajhi NN, Khayat LT, Alsulami MK, Al Marri SA, Alshuqaybi HM, Aldhafyan SR, Al Jabir FM, Albaqami NA, Alyami AM, Alamrani AM, Abusabir DN, Alkhaldi AN, Al-Hawaj F. Ruptured Isolated Common Iliac Artery Aneurysm Masquerading as Renal Colic. Cureus. 2021 Nov 19;13(11): e19752. doi: 10.7759/cureus.19752.</mixed-citation><mixed-citation xml:lang="en">Alfahhad MF, Qasem HA, Alrajhi NN, Khayat LT, Alsulami MK, Al Marri SA, Alshuqaybi HM, Aldhafyan SR, Al Jabir FM, Albaqami NA, Alyami AM, Alamrani AM, Abusabir DN, Alkhaldi AN, Al-Hawaj F. Ruptured Isolated Common Iliac Artery Aneurysm Masquerading as Renal Colic. Cureus. 2021 Nov 19;13(11): e19752. doi: 10.7759/cureus.19752.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Barnett D, Kinnear N, Yao HH, Chee J. Renal colic causing Boerhaave syndrome. Transl Androl Urol. 2020 Apr;9(2):828–830. doi: 10.21037/tau.2019.12.11.</mixed-citation><mixed-citation xml:lang="en">Barnett D, Kinnear N, Yao HH, Chee J. Renal colic causing Boerhaave syndrome. Transl Androl Urol. 2020 Apr;9(2):828–830. doi: 10.21037/tau.2019.12.11.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ganti S, Sohil P. Renal Colic: A Red Herring for Mucocele of the Appendiceal Stump. Case Rep Emerg Med. 2018 Dec 6;2018:2502183. doi: 10.1155/2018/2502183</mixed-citation><mixed-citation xml:lang="en">Ganti S, Sohil P. Renal Colic: A Red Herring for Mucocele of the Appendiceal Stump. Case Rep Emerg Med. 2018 Dec 6;2018:2502183. doi: 10.1155/2018/2502183</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Imamoglu M, Aygun A, Bekar O, Erdem E, Cicek M, Tatli O, Karaca Y, Sahin A, Turkmen S, Turedi S. A retrospective analysis of nebulized versus intravenous fentanyl for renal colic. Am J Emerg Med. 2017 May;35(5):757–763. doi: 10.1016/j.ajem.2017.01.026.</mixed-citation><mixed-citation xml:lang="en">Imamoglu M, Aygun A, Bekar O, Erdem E, Cicek M, Tatli O, Karaca Y, Sahin A, Turkmen S, Turedi S. A retrospective analysis of nebulized versus intravenous fentanyl for renal colic. Am J Emerg Med. 2017 May;35(5):757–763. doi: 10.1016/j.ajem.2017.01.026.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Kilic Y, Gokdogan Y, Abdullah S. Spontaneous renal pelvis haematoma presenting as renal colic. BJR Case Rep. 2018 Oct 2;5(1):20180086. doi: 10.1259/bjrcr.20180086.</mixed-citation><mixed-citation xml:lang="en">Kilic Y, Gokdogan Y, Abdullah S. Spontaneous renal pelvis haematoma presenting as renal colic. BJR Case Rep. 2018 Oct 2;5(1):20180086. doi: 10.1259/bjrcr.20180086.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mann U, Jain K, Wong R, Li Z, Eng A, Blachman-Braun R, Patel P. Predictors of mortality for patients admitted to the intensive care unit with obstructing septic stones. Can Urol Assoc J. 2021 Nov;15(11): E 593-E 597. doi: 10.5489/cuaj.7118.</mixed-citation><mixed-citation xml:lang="en">Mann U, Jain K, Wong R, Li Z, Eng A, Blachman-Braun R, Patel P. Predictors of mortality for patients admitted to the intensive care unit with obstructing septic stones. Can Urol Assoc J. 2021 Nov;15(11): E 593-E 597. doi: 10.5489/cuaj.7118.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Reyner K, Heffner AC, Karvetski CH. Urinary obstruction is an important complicating factor in patients with septic shock due to urinary infection. Am J Emerg Med. 2016 Apr;34(4):694–6. doi: 10.1016/j.ajem.2015.12.068.</mixed-citation><mixed-citation xml:lang="en">Reyner K, Heffner AC, Karvetski CH. Urinary obstruction is an important complicating factor in patients with septic shock due to urinary infection. Am J Emerg Med. 2016 Apr;34(4):694–6. doi: 10.1016/j.ajem.2015.12.068.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Schoenfeld EM, Pekow PS, Shieh MS, Scales CD Jr, Lagu T, Lindenauer PK. The Diagnosis and Management of Patients with Renal Colic across a Sample of US Hospitals: High CT Utilization Despite Low Rates of Admission and Inpatient Urologic Intervention. PLoS One. 2017 Jan 3;12(1): e0169160. doi: 10.1371/journal.pone.0169160.</mixed-citation><mixed-citation xml:lang="en">Schoenfeld EM, Pekow PS, Shieh MS, Scales CD Jr, Lagu T, Lindenauer PK. The Diagnosis and Management of Patients with Renal Colic across a Sample of US Hospitals: High CT Utilization Despite Low Rates of Admission and Inpatient Urologic Intervention. PLoS One. 2017 Jan 3;12(1): e0169160. doi: 10.1371/journal.pone.0169160.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Schoenfeld EM, Shieh MS, Pekow PS, Scales CD, Jr, Munger JM, Lindenauer PK. Association of patient and visit characteristics with rate and timing of urologic procedures for patients discharged from the emergency department with renal colic. JAMA Netw Open. 2019;2: e1916454.</mixed-citation><mixed-citation xml:lang="en">Schoenfeld EM, Shieh MS, Pekow PS, Scales CD, Jr, Munger JM, Lindenauer PK. Association of patient and visit characteristics with rate and timing of urologic procedures for patients discharged from the emergency department with renal colic. JAMA Netw Open. 2019;2: e1916454.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Thia I, Saluja M. An update on management of renal colic. Aust J Gen Pract. 2021 Jul;50(7):445–449. doi: 10.31128/AJGP-11–20–5751.</mixed-citation><mixed-citation xml:lang="en">Thia I, Saluja M. An update on management of renal colic. Aust J Gen Pract. 2021 Jul;50(7):445–449. doi: 10.31128/AJGP-11–20–5751.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Türk C, Petřík A, Sarica K, Seitz C, Skolarikos A, Straub M, Knoll T. EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis. Eur Urol. 2016 Mar;69(3):468–74. doi: 10.1016/j.eururo.2015.07.040</mixed-citation><mixed-citation xml:lang="en">Türk C, Petřík A, Sarica K, Seitz C, Skolarikos A, Straub M, Knoll T. EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis. Eur Urol. 2016 Mar;69(3):468–74. doi: 10.1016/j.eururo.2015.07.040</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Громов А. И., Буйлов В. М. Лучевая диагностика и терапия в урологии: национальное руководство. М.: ГЭОТАР-Медиа; 2011.</mixed-citation><mixed-citation xml:lang="en">Gromov A. I., Builov V. M. Radiation diagnostics and therapy in urology. М.: GEOTAR-Media; 2011 (in Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А. Д., Аполихин О. И., Сивков А. В., Анохин Н. В., Гаджиев Н. К., Малхасян В. А., Акопян Г. Н., Просянников М. Ю. Заболеваемость мочекаменной болезнью в Российской Федерации с 2005 по 2020 гг. Экспериментальная и клиническая урология 2022;15(2)10–17; https://doi.org/10.29188/2222–8543–2022–15–2–10–17</mixed-citation><mixed-citation xml:lang="en">Kaprin A. D., Apolikhin O. I., Sivkov A. V., Anokhin N. V., Gadzhiev N. K., Malkhasyan V. A., Akopyan G. N., Prosyannikov M. Y. Incidence of urolithiasis in the Russian Federation from 2005 to 2020. Experimental and Clinical Urology 2022;15(2)10–17. https://doi.org/10.29188/2222–8543–2022–15–2–10–17</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Кульченко Н. Г., Векильян М. А. Анализ антибактериальной чувствительности E. Coli у пациентов с хроническим калькулезным пиелонефритом. Вестник Российского университета дружбы народов. Серия: Медицина. 2016; 3: 125–131</mixed-citation><mixed-citation xml:lang="en">Kulchenko N. G., Vekilyan M. A. Analysis of antibiotic sensitivity of e. coli in patients with chronic calculous pyelonephritis. RUDN Journal of Medicine. 2016;3:125–131. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Кульченко Н. Г., Векильян М. А. Данные об изменениях антибактериальной чувствительности микрофлоры к антибиотикам у пациентов с хроническим калькулезным пиелонефритом на фоне сахарного диабета 2 типа. Вестник медицинского института «РЕАВИЗ»: реабилитация, врач и здоровье. 2016; 3 (23): 85–90.</mixed-citation><mixed-citation xml:lang="en">Kulchenko NG, Vekilian MA. Data of change of microflora antibacterial sensitivity to antibiotics in patients with chronic calculous pyelonephritis and diabetes mellitus of type 2. Bulletin of the Medical Institute “REAVIZ” (Rehabilitation, Doctor and Health). 2016;3(23):85–90. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Петров В. И., Винаров А. З., Векильян М. А., Кульченко Н. Г. Изменение структуры возбудителей калькулезного пиелонефрита, осложненного сахарным диабетом 2 типа, в урологическом стационаре Волгограда. Урология. 2016;4:58–62.</mixed-citation><mixed-citation xml:lang="en">Petrov VI, Vinarov AZ, Vekilyan MA, Kulchenko NG. Changes in the structure of pathogens of calculous pyelonephritis complicated with diabetes mellitus type ii, in the hospital urology of the city of Volgograd. Urologiia. 2016;4:58–62. (In Russ.)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
