medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»medalphabet-364Research ArticleСтатьиИнтраоперационная лучевая терапия: вчера, сегодня, завтра (обзор литературы)Intraoperative radiation therapy: yesterday, today, futureТер-ОванесовМ. Д.Ter-OvanesovM. D.noemail@neicon.ruКукошМ. Ю.KukoshM. Yu.noemail@neicon.ruФГАОУ ВО «Российский университет дружбы народов»; ГБУЗ «Городская клиническая больница № 40» Департамента здравоохранения г. МосквыРоссияPeople’s Friendship University of Russia; Municipal Clinical Hospital No. 40Russian Federation201712112017335Диагностика и онкотерапия2328Copyright © Тер-Ованесов М.Д., Кукош М.Ю., 20172017Тер-Ованесов М.Д., Кукош М.Ю.Ter-Ovanesov M.D., Kukosh M.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/364

В обзоре литературы дана историческая справка и представлены современные подходы к интраоперационной лучевой терапии (ИОЛТ) как высокоэффективному методу противоопухолевого лечения. Обобщен обширный опыт применения данного метода при различных злокачественных новообразованиях, оценены влияние на локорегиональный контроль, безрецидивную и общую выживаемость, качество жизни, токсичность и летальность. Описаны особенности дозиметрического планирования, визуализации мишени и перспективы ИОЛТ: стереоскопическая навигация и интеграция лапароскопических и прероботических хирургических техник с ИОЛТ.

The article gives a review of the historical reference and presents the innovative approaches to intraoperative radiation therapy (IORT) procedures as effective method of oncology treatment. The authors summarize big experience to use this method in the different cancer diseases, estimate the influence on locoregional control, disease-free survival and overall survival, quality of life, toxicity, postoperative mortality. Also authors describe the features of dose planning, perspectives of IORT: stereotactic navigation, intraoperative imaging, and integration of laparoscopic and pre-robotic techniques with this method.

лучевая терапияинтраоперационная лучевая терапиялинейные ускорителихирургическая навигациярак желудкарак поджелудочной железыsurgeryradiation oncologyintraoperative radiation therapyintraoperative electron-beam radiation therapycytoreductive surgeryhyperthermic intraperitoneal chemotherapycarcinoma of the stomachpancreasReferencesЗавьялов А. А., Мусабаева А.И., Лисин В. А. Пятнадцатилетний опыт применения интраоперационной лучевой терапии // Сибирский онкологический журнал. - 2004.- No 2-3.- С. 75-84.Завьялов А. А., Мусабаева А.И., Лисин В. А. Пятнадцатилетний опыт применения интраоперационной лучевой терапии // Сибирский онкологический журнал. - 2004.- No 2-3.- С. 75-84.Отт П.А., Привалов А. В., Важенин А. В., Е. А. Надвикова, и др. Непосредственные результаты комбинированного лечения интраоперационной лучевой терапией сарком мягких тканей // Вопросы онкологии.- 2013. - том 59, No 5. - С. 602-605.Отт П.А., Привалов А. В., Важенин А. В., Е. А. Надвикова, и др. 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The authors declare that there are no conflicts of interest present.