<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2024-2-47-49</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3618</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Аденома гипофиза. Клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Pituitary adenoma. Clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3276-7615</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болдырева</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Boldyreva</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Болдырева Юлия Викторовна - к.м.н., доцент, доцент кафедры биологической химии Института фармации.</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Boldyreva Yulia V. - PhD Med, associate professor at Dept of Biological Chemistry at the Institute of Pharmacy.</p><p>Tyumen</p></bio><email xlink:type="simple">tgma.06@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5405-7182</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедев Илья Аркадьевич - д.м.н., профессор кафедры топографической анатомии и оперативной хирургии с курсом остеопатии Института фундаментальной медицины.</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Lebedev Ilya A. - DM Sci (habil.), professor at Dept of Topographic Anatomy and Operative Surgery with a Course of Osteopathy at the Institute of Fundamental.Tyumen</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8921-2979</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Собинов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobinov</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Собинов Руслан Алексеевич - студент 3 курса.</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Sobinov Ruslan A. - third year student</p><p>Tyumen</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7534-9552</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гавриленко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavrilenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гавриленко Елена Александровна - студентка 4 курса.</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Gavrilenko Elena A. - 4th year student.</p><p>Tyumen</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вакуленко</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vakulenko</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вакуленко Юлия Андреевна - студентка 3 курса.</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Vakulenko Yulia A. - 3rd year student.</p><p>Tyumen</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Тюменский Государственный Медицинский Университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>27</day><month>04</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><issue-title>Неврология и психиатрия (1)</issue-title><fpage>47</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Болдырева Ю.В., Лебедев И.А., Собинов Р.А., Гавриленко Е.А., Вакуленко Ю.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Болдырева Ю.В., Лебедев И.А., Собинов Р.А., Гавриленко Е.А., Вакуленко Ю.А.</copyright-holder><copyright-holder xml:lang="en">Boldyreva Y.V., Lebedev I.A., Sobinov R.A., Gavrilenko E.A., Vakulenko Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3618">https://www.med-alphabet.com/jour/article/view/3618</self-uri><abstract><p>В статье представлено описание клинического случая аденомы гипофиза. Известно, что она является опухолевым образованием доброкачественного характера из железистой ткани передней доли. Её рост сопровождается эндокринными, неврологическими  и нейроофтальмологическими осложнениями, что является серьезной проблемой в связи с вовлечением в патологический процесс важнейших анатомических структур и обуславливает сложность радикальной резекции опухоли при минимальном количестве осложнений.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a clinical case of pituitary adenoma. It is known, that a pituitary adenoma is a benign tumor formation emanating from the glandular tissue of the anterior pituitary gland. Its growth is accompanied by endocrine, neurological and neuro-ophthalmological complications, which is a serious problem in modern neurosurgery due to the involvement of the most important anatomical structures in the pathological process and makes radical tumor resection difficult with a minimum number of complications.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аденома</kwd><kwd>гипофиз</kwd><kwd>осложнения</kwd><kwd>поля зрения</kwd><kwd>опухоль</kwd><kwd>лечение</kwd><kwd>гормоны</kwd></kwd-group><kwd-group xml:lang="en"><kwd>adenoma</kwd><kwd>pituitary gland</kwd><kwd>complications</kwd><kwd>visual fields</kwd><kwd>tumor</kwd><kwd>treatment</kwd><kwd>hormones</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Липатенкова А. К., Дзеранова Л. К., Пигарова Е. А., Астафьева Л. И., Григорьев А. Ю., Шишкина Л. В., Черебило В. Ю., Эктова А. П. «Немые» аденомы гипофиза: обзор литературы и описание серии клинических случаев. Ожирение и метаболизм. 2015; 12 (2): 40–46</mixed-citation><mixed-citation xml:lang="en">Lipatenkova A. K., Dzeranova L. K., Pigarova E. A., Astaf’eva L.I., Grigor’ev A. Ju., Shishkina L. V., Cherebilo V. Ju., Jektova A. P. Silent pituitary adenomas: review and clinical cases. Ozhirenie i metabolism – Obesity and metabolism. 2015; 12 (2): 40–46 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Калинин П. Л., Трунин Ю. Ю., Фомичев Д. В., Чернов И. В., Рыжова М. В. Агрессивные аденомы гипофиза (обзор литературы и клиническое наблюдение). Опухоли головы и шеи. 2017; 7 (4): 74–80</mixed-citation><mixed-citation xml:lang="en">Kalinin P. L., Trunin Ju. Ju., Fomichev D. V., Chernov I. V., Ryzhova M. V. Aggressive forms of pituitary adenomas (literature review and clinical observation). Opuholi golovy i shei – Head and neck tumors. 2017; 7 (4): 74–80 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Dai C., Feng M., Liu X. et al. Refractory pituitary adenoma: a novel classification for pituitary tumors. Oncotarget. 2016; 7 (50): 83657–83668. DOI: 10.18632/oncotarget.13274.</mixed-citation><mixed-citation xml:lang="en">Dai C., Feng M., Liu X. et al. Refractory pituitary adenoma: a novel classification for pituitary tumors. Oncotarget. 2016; 7 (50): 83657–83668. DOI: 10.18632/oncotarget.13274.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Dillard T. H., Gultekin S. H., Delashaw J. B. Jr. et al. Temozolomide for corticotroph pituitary adenomas refractory to standard therapy. Pituitary. 2011; 14 (1): 80–91. DOI: 10.1007/s11102–010–0264–1.</mixed-citation><mixed-citation xml:lang="en">Dillard T. H., Gultekin S. H., Delashaw J. B. Jr. et al. Temozolomide for corticotroph pituitary adenomas refractory to standard therapy. Pituitary. 2011; 14 (1): 80–91. DOI: 10.1007/s11102–010–0264–1.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Priola S. M., Esposito F., Cannavò S. et al. Aggressive pituitary adenomas: the dark side of the moon. World Neurosurg. 2017; 97: 140–155. DOI: 10.1016/j.wneu.2016.09.092.</mixed-citation><mixed-citation xml:lang="en">Priola S. M., Esposito F., Cannavò S. et al. Aggressive pituitary adenomas: the dark side of the moon. World Neurosurg. 2017; 97: 140–155. DOI: 10.1016/j.wneu.2016.09.092.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Liu J. K., Patel J., Eloy J. A. The role of temozolomide in the treatment of aggressive pituitary tumors. J Clin Neurosci. 2015; 22 (6): 923–929. DOI: 10.1016/j.jocn.2014.12.007.</mixed-citation><mixed-citation xml:lang="en">Liu J. K., Patel J., Eloy J. A. The role of temozolomide in the treatment of aggressive pituitary tumors. J Clin Neurosci. 2015; 22 (6): 923–929. DOI: 10.1016/j.jocn.2014.12.007.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Chiloiro S., Doglietto F., Trapasso B. et al. Typical and atypical pituitary adenomas: a single-center analysis of outcome and prognosis. Neuroendocrinology. 2015; 101 (2): 143–150. DOI: 10.1159/000375448.</mixed-citation><mixed-citation xml:lang="en">Chiloiro S., Doglietto F., Trapasso B. et al. Typical and atypical pituitary adenomas: a single-center analysis of outcome and prognosis. Neuroendocrinology. 2015; 101 (2): 143–150. DOI: 10.1159/000375448.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Zaidi H. A., Cote D. J., Dunn I. F., Laws E. R. Jr. Predictors of aggressive clinical phenotype among immunohistochemically confirmed atypical adenomas. J Clin Neurosci. 2016; 34: 246–251. DOI: 10.1016/j.jocn.2016.09.014.</mixed-citation><mixed-citation xml:lang="en">Zaidi H. A., Cote D. J., Dunn I. F., Laws E. R. Jr. Predictors of aggressive clinical phenotype among immunohistochemically confirmed atypical adenomas. J Clin Neurosci. 2016; 34: 246–251. DOI: 10.1016/j.jocn.2016.09.014.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
