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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-35-12-18</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3491</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Острый коронарный синдром у пациентов с онкологическими заболеваниями</article-title><trans-title-group xml:lang="en"><trans-title>Acute coronary syndrome in patients with oncological diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2619-1592</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Близнюк</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bliznyuk</surname><given-names>S. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Близнюк Светлана Александровна, к.м.н., зав. кардиологическим отделением, н.с. </p><p> </p></bio><bio xml:lang="en"><p>Bliznyuk Svetlana A., PhD Med, head of Cardiology Dept, researche</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8633-7012</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комарова</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Komarova</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Комарова Анна Григорьевна, к.м.н., зам. гл. врача по медицинской части по региональному сосудистому центру, в.н.с., врач-кардиолог</p></bio><bio xml:lang="en"><p>Komarova Anna G., PhD Med, deputy chief physician for medical affairs at Regional Vascular Centre, leading researcher, cardiologist</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0912-6342</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Либов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Libov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Либов Игорь Айзикович, к.м.н., с.н.с. </p></bio><bio xml:lang="en"><p>Libov Igor A., PhD Med, senior researcher</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2701-3525</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ляхова</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyakhova</surname><given-names>N. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ляхова Наталия Леонидовна, к.м.н., зав. кардиологическим отделением, н.с., врач-кардиолог </p></bio><bio xml:lang="en"><p>Lyakhova Natalia L., PhD Med, head of Cardiology Dept, researcher, cardiologist</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8614-8150</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеев</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseev</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеев Владимир Григорьевич, д.м.н., проф., врач-терапевт</p></bio><bio xml:lang="en"><p>Alekseev Vladimir G., DM Sci (habil.), professor, general practitioner</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ г. Москвы «Городская клиническая больница имени С. П. Боткина Департамента здравоохранения Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital n.a. S. P. Botkin</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>18</day><month>01</month><year>2024</year></pub-date><volume>0</volume><issue>35</issue><issue-title>Кардиология. Неотложная медицина (4)</issue-title><fpage>12</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Близнюк С.А., Комарова А.Г., Либов И.А., Ляхова Н.Л., Алексеев В.Г., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Близнюк С.А., Комарова А.Г., Либов И.А., Ляхова Н.Л., Алексеев В.Г.</copyright-holder><copyright-holder xml:lang="en">Bliznyuk S.А., Komarova A.G., Libov I.A., Lyakhova N.L., Alekseev V.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3491">https://www.med-alphabet.com/jour/article/view/3491</self-uri><abstract><p>Цель данной работы – повысить настороженность врачей, курирующих онкологических больных, в отношении высокого риска развития у них острого коронарного синдрома (ОКС) и понимание особенностей патогенетических механизмов его развития. Противоопухолевая терапия должна быть персонифицирована и согласована междисциплинарной командой с оценкой ее влияния на риск развития ОКС, особенно у больных высокого сердечно-сосудистого риска. С учетом ограниченного количества исследований, принципы ведения онкологических больных с ОКС должны быть основаны на оценке ишемических и геморрагических рисков.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of this work is to increase the alertness of doctors treating cancer patients due to the high risk of developing acute coronary syndrome (ACS) and understanding the pathogenetic mechanisms of the development of ACS. Antitumor therapy should be personalized and agreed upon by an interdisciplinary team with an assessment of the impact on the risk of developing ACS, especially in patients with high cardiovascular risk. Given the limited number of studies, principles for the management of cancer patients with ACS should be based on an assessment of ischemic and hemorrhagic risks.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый коронарный синдром</kwd><kwd>инфаркт миокарда</kwd><kwd>рак</kwd><kwd>онкологические заболевания</kwd><kwd>химиотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute coronary syndrome</kwd><kwd>myocardial infarction</kwd><kwd>cancer</kwd><kwd>oncological diseases</kwd><kwd>chemotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Navi B. B., Reiner A. S., Kamel H., Iadecola C., Okin P. M., Tagawa S. T., Panageas K. S., DeAngelis L. M. Arterial thromboembolic events preceding the diagnosis of cancer in old er persons. Blood. 2019; 133 (8): 781–789. https://doi.org/10.1182/blood2018–06–860874</mixed-citation><mixed-citation xml:lang="en">Navi B. 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