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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-34-29-32</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3488</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Клинический случай COVID-19 у ребенка с герпесвирусной инфекцией</article-title><trans-title-group xml:lang="en"><trans-title>Clinical case of COVID‑19 in child with herpesvirus infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мальцева</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maltseva</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мальцева Юлия Вадимовна, к.м.н., ст. преподаватель кафедры внутренних болезней,</p><p>Орел.</p></bio><bio xml:lang="en"><p>Maltseva Yulia V., PhD Med, senior lecturer at Dept of Internal Medicine,</p><p>Orel.</p></bio><email xlink:type="simple">79155022098@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Надточеева</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nadtocheeva</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Надточеева Любовь Александровна, зав. вторым инфекционно-боксированным отделением № 2</p><p>Орел.</p></bio><bio xml:lang="en"><p>Nadtocheeva Lyubov A., head of Second Infectious-Boxed Dept No. 2,</p><p>Orel.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королева</surname><given-names>Л. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Koroleva</surname><given-names>L. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Королева Лилия Юрьевна, ст. преподаватель кафедры внутренних болезней,</p><p>Орел.</p></bio><bio xml:lang="en"><p>Koroleva Liliya Yu., senior lecturer at Dept of Internal Medicine,</p><p>Orel.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Орловский государственный университет имени И.С. Тургенева»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Orel State University n.a. I. S. Turgenev</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>БУЗ Орловской области «Научно-клинический многопрофильный центр медицинской помощи матерям и детям имени З.И. Круглой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific and Clinical Multidisciplinary Centre for Medical Care for Mothers and Children n.a. Z.I. Krugloy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>18</day><month>01</month><year>2024</year></pub-date><volume>0</volume><issue>34</issue><issue-title>Обозрение (3)</issue-title><fpage>29</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мальцева Ю.В., Надточеева Л.А., Королева Л.Ю., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Мальцева Ю.В., Надточеева Л.А., Королева Л.Ю.</copyright-holder><copyright-holder xml:lang="en">Maltseva Y.V., Nadtocheeva L.A., Koroleva L.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3488">https://www.med-alphabet.com/jour/article/view/3488</self-uri><abstract><p>По данным Минздрава России (2022), среди детей зарегистрировано 12–13 % случаев COVID‑19. В настоящее время COVID‑19 рассматривается как системное заболевание, характеризующееся как респираторными, так и внелегочными симптомами, в том числе дерматологическими проявлениями. По данным ряда зарубежных авторов, частота кожных проявлений при COVID‑19 у детей составляет от 0,2 до 20,4% случаев. В литературе представлены немногочисленные случаи экзантемы у детей, характеризующейся ливедо, пятнисто-папулезными, уртикарными, папуло-везикулезными элементами, что обусловливает актуальность данной проблемы. Продемонстрированный нами клинический случай коронавирусной инфекции у ребенка на фоне дерматологических проявлений ассоциирован с реактивацией ВЭБ-инфекции, что довольно редко встречается в практической деятельности педиатра и тем самым может вызывать определенные сложности в проведении дифференциальной диагностики с рядом других заболеваний.</p></abstract><trans-abstract xml:lang="en"><p>According to the Ministry of Health of the Russian Federation (2022) 12–13% of cases of COVID‑19 were registered among children. Currently, COVID‑19 is considered as a systemic disease characterized by both respiratory and extrapulmonary symptoms, including dermatological manifestations. According to a number of foreign authors, the frequency of skin manifestations in COVID‑19 in children ranges from 0.2% to 20.4% of cases. The literature presents a few cases of exanthema in children, characterized by livedo, spotted-papular, urticar, papulo-vesicular elements, which determines the relevance of this problem. The clinical case of coronavirus infection in a child demonstrated by us against the background of dermatological manifestations is associated with the reactivation of EBV infection, which is quite rare in the practice of a pediatrician, thereby may cause certain difficulties in conducting differential diagnosis with a number of other diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>клинический случай</kwd><kwd>дети</kwd><kwd>COVID‑19</kwd><kwd>вирус Эпштейна–Барр</kwd><kwd>экзантема</kwd></kwd-group><kwd-group xml:lang="en"><kwd>clinical case</kwd><kwd>children</kwd><kwd>COVID‑19</kwd><kwd>Epstein-Barr virus</kwd><kwd>exanthema</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Korber B, Fischer WM, Gnanakaran S, Yoon H, Theiler J, Abfalterer W, et al. Tracking changes in SARS-CoV‑2 spike: Evidence that D614G increases infectivity of the COVID‑19virus. 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