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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-31-43-46</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3450</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Поражение суставов и позвоночника у больных воспалительными заболеваниями кишечника</article-title><trans-title-group xml:lang="en"><trans-title>Joint and spine damage in patients with inflammatory bowel diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8974-836X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>Д. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>D. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарасова Дарья Дмитриевна - ассистент кафедры госпитальной терапии, ВПТ.</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Daria D. Tarasova - assistant at Dept of Hospital, Military and Field Therapy.</p><p>Volgograd</p></bio><email xlink:type="simple">bdd_34@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0438-8554</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шилова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilova</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шилова Людмила Николаевна - д.м.н., зав. кафедрой госпитальной терапии, ВПТ.</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Lyudmila N. Shilova - DM Sci (habil.), head of Dept of Hospital, Military and Field Therapy.</p><p>Volgograd</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Волгоградский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volgograd State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>13</day><month>01</month><year>2024</year></pub-date><volume>0</volume><issue>31</issue><issue-title>Ревматология в общей врачебной практике (2)</issue-title><fpage>43</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тарасова Д.Д., Шилова Л.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Тарасова Д.Д., Шилова Л.Н.</copyright-holder><copyright-holder xml:lang="en">Tarasova D.D., Shilova L.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3450">https://www.med-alphabet.com/jour/article/view/3450</self-uri><abstract><p>Поражение суставов и позвоночника является частым внекишечным проявлением (ВКП) воспалительных заболеваний кишечника (ВЗК). Исследования показывают генетическую и иммунологическую связь поражения суставов и кишечного воспаления. Могут развиваться олиго- и полиартриты мелких и крупных суставов, артралгии, анкилозирующий спондилит (АС). Артриты при ВЗК являются серонегативными, характеризуются неэрозивным и недеструктивным поражением. Суставной синдром чаще ассоциирован с тяжелым течением ВЗК и большой протяженностью поражения. Артрит при ВЗК в основном дебютирует одновременно с кишечным воспалением или возникает после, но может предшествовать развитию ВЗК. Поражение суставов может дебютировать с развернутой клинической картиной, также описаны случаи латентного течения, что осложняет своевременную постановку диагноза. Сочетание суставного синдрома и кишечного воспаления требует междисциплинарного подхода.</p></abstract><trans-abstract xml:lang="en"><p>Damage to the joints and spine is a frequent extra-intestinal manifestation of inflammatory bowel diseases (IBD). Studies show a genetic and immunological link between joint damage and intestinal inflammation. Oligo- and polyarthritis of small and large joints, arthralgia, ankylosing spondylitis may develop. Arthritis in IBD is seronegative, characterized by non-erosive and non-destructive lesions. Articular syndrome is more often associated with a severe course of IBD and a large extent of the lesion. Arthritis with IBD, basically, debuts simultaneously with intestinal inflammation or occurs after, but may precede the development of IBD. Joint damage can make its debut with a detailed clinical picture, cases of latent course are also described, which complicates the timely diagnosis. The combination of joint syndrome and intestinal inflammation requires an interdisciplinary approach.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>анкилозирующий спондилит</kwd><kwd>язвенный колит</kwd><kwd>болезнь Крона</kwd><kwd>внекишечные проявления</kwd><kwd>поражение суставов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ankylosing spondylitis</kwd><kwd>ulcerative colitis</kwd><kwd>Crohn's disease</kwd><kwd>extra-intestinal manifestations</kwd><kwd>joint damage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fragoulis G.E. et al. Inflammatory bowel diseases and spondyloarthropathies: From pathogenesis to treatment. World Journal of Gastroenterology. 2019. V. 25. No. 18. P. 2162.</mixed-citation><mixed-citation xml:lang="en">Fragoulis G.E. et al. Inflammatory bowel diseases and spondyloarthropathies: From pathogenesis to treatment. World Journal of Gastroenterology. 2019. V. 25. No. 18. P. 2162.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Kuhn K. A. et al. Bacteroidales recruit IL-6-producing intraepithelial lymphocytes in the colon to promote barrier integrity. Mucosal Immunology. 2018. V. 11. No. 2. P. 357–368.</mixed-citation><mixed-citation xml:lang="en">Kuhn K. A. et al. Bacteroidales recruit IL-6-producing intraepithelial lymphocytes in the colon to promote barrier integrity. Mucosal Immunology. 2018. V. 11. No. 2. P. 357–368.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Frank D. N. et al. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proceedings of the national academy of sciences. 2007. V. 104. No. 34. P. 13780–13785.</mixed-citation><mixed-citation xml:lang="en">Frank D. N. et al. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proceedings of the national academy of sciences. 2007. V. 104. No. 34. P. 13780–13785.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Шелыгин Ю. А. и др. Клинические рекомендации. Болезнь Крона (К50), взрослые. Колопроктология. 2023. Т. 22. № 3. С. 10–49. https://doi.org/10.33878/2073–7556–2023–22–3–10–49</mixed-citation><mixed-citation xml:lang="en">Shelygin Yu.A., at al. Clinical guidelines. Crohn’s disease (К50), adults. Koloproktologia. 2023; 22 (3): 10–49. https://doi.org/10.33878/2073–7556–2023–22–3–10–49</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Vavricka S.R. et al. Frequency and risk factors for extraintestinal manifestations in the Swiss inflammatory bowel disease cohort. Official Journal of the American College of Gastroenterology. ACG. 2011. V. 106. No. 1. P. 110–119.</mixed-citation><mixed-citation xml:lang="en">Vavricka S.R. et al. Frequency and risk factors for extraintestinal manifestations in the Swiss inflammatory bowel disease cohort. Official Journal of the American College of Gastroenterology. ACG. 2011. V. 106. No. 1. P. 110–119.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Dorofeyev A.E., Vasilenko I.V., Rassokhina O.A. Joint extraintestinal manifestations in ulcerative colitis. Digestive Diseases. 2009. V. 27. No. 4. P. 502–510.</mixed-citation><mixed-citation xml:lang="en">Dorofeyev A.E., Vasilenko I.V., Rassokhina O.A. Joint extraintestinal manifestations in ulcerative colitis. Digestive Diseases. 2009. V. 27. No. 4. P. 502–510.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Zippi M. et al. Extraintestinal manifestations in a large series of Italian inflammatory bowel disease patients. World Journal of Gastroenterology: WJG. 2014. V. 20. No. 46. P. 17463.</mixed-citation><mixed-citation xml:lang="en">Zippi M. et al. Extraintestinal manifestations in a large series of Italian inflammatory bowel disease patients. World Journal of Gastroenterology: WJG. 2014. V. 20. No. 46. P. 17463.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Белоусова Е. А. и др. Социально-демографическая характеристика, особенности течения и варианты лечения воспалительных заболеваний кишечника в России. Результаты двух многоцентровых исследований. Альманах клинической медицины. 2018. Т. 46. № 5. С. 445–463. DOI: 10.18786/2072–0505–2018–46–5–445–463.</mixed-citation><mixed-citation xml:lang="en">Belousova EA at al. Social and demographic characteristics, Features of disease course and treatment options of inflammatory bower disease in Russia: Results of two multicenter studies. Almanac of Clinical Medicine. 2018; 46 (5): 445–63. DOI: 10.18786/2072–0505–2018–46–5–445–463.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">The First European Evidence-based Consensus on Extra-Intestinal Manifestations in IBD. Journal of Crohn's and Colitis – 2016. No. 10 (3). Pр. 239–254.</mixed-citation><mixed-citation xml:lang="en">The First European Evidence-based Consensus on Extra-Intestinal Manifestations in IBD. Journal of Crohn's and Colitis – 2016. No. 10 (3). Pр. 239–254.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Sieper J. Axial spondyloarthritis. J. Sieper, D. Poddubnyy. Lancet. 2017. No. 390 (10089). P. 73–84.</mixed-citation><mixed-citation xml:lang="en">Sieper J. Axial spondyloarthritis. J. Sieper, D. Poddubnyy. Lancet. 2017. No. 390 (10089). P. 73–84.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Российские клинические рекомендации. Ревматология. Под ред. Е. Л. Насонова. М.: ГЭОТАР-Медиа; 2017. 464 с.</mixed-citation><mixed-citation xml:lang="en">Russian clinical guidelines. Rheumatology. Ed. E.L. Nasonov. M.: GEOTAR-Media; 2017. 464 p.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Karreman M.C. et al. The prevalence and incidence of axial and peripheral spondyloarthritis in inflammatory bowel disease: A systematic review and meta-analysis. Journal of Crohn's and Colitis. 2017. Т. 11. No. 5. P. 631–642.</mixed-citation><mixed-citation xml:lang="en">Karreman M.C. et al. The prevalence and incidence of axial and peripheral spondyloarthritis in inflammatory bowel disease: A systematic review and meta-analysis. Journal of Crohn's and Colitis. 2017. Т. 11. No. 5. P. 631–642.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Sepriano A., Rubio R., Ramiro S., Landewé R., van der Heijde D. Performance of the ASAS classification criteria for axial and peripheral spondyloarthritis: A systematic literature review and meta-analysis. Ann Rheum Dis. 2017; 76: 886–90. DOI: 10.1136/annrheumdis-2016–210747.</mixed-citation><mixed-citation xml:lang="en">Sepriano A., Rubio R., Ramiro S., Landewé R., van der Heijde D. Performance of the ASAS classification criteria for axial and peripheral spondyloarthritis: A systematic literature review and meta-analysis. Ann Rheum Dis. 2017; 76: 886–90. DOI: 10.1136/annrheumdis-2016–210747.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Brakenhoff L. The joint-gut axis in inflammatory bowel diseases. L. Brakenhoff, D.M. van der Heijde, D.W. Hommes [et al.]. Journal of Crohn’s and Colitis. 2010. No. 4. P. 257–268.</mixed-citation><mixed-citation xml:lang="en">Brakenhoff L. The joint-gut axis in inflammatory bowel diseases. L. Brakenhoff, D.M. van der Heijde, D.W. Hommes [et al.]. Journal of Crohn’s and Colitis. 2010. No. 4. P. 257–268.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Rogler G. et al. Extraintestinal manifestations of inflammatory bowel disease: Current concepts, treatment, and implications for disease management. Gastroenterology. 2021. V. 161. No. 4. P. 1118–1132.</mixed-citation><mixed-citation xml:lang="en">Rogler G. et al. Extraintestinal manifestations of inflammatory bowel disease: Current concepts, treatment, and implications for disease management. Gastroenterology. 2021. V. 161. No. 4. P. 1118–1132.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Greenstein A. Extra-intestinal complications of Crohn’s disease and ulcerative colitis A. Greenstein, H. Janowitz, D. Sachar. Medicine. 1976. No. 55. Pр. 401–412.</mixed-citation><mixed-citation xml:lang="en">Greenstein A. Extra-intestinal complications of Crohn’s disease and ulcerative colitis A. Greenstein, H. Janowitz, D. Sachar. Medicine. 1976. No. 55. Pр. 401–412.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Salvarani C. Clinical features and epidemiology of spondylarthritis associated with inflammatory bowel disease. C. Salvarani, W. Fries. World J Gastroenterol. 2009. No. 15 (20). Alvilde M Ossum, et al. P. 2449–2455.</mixed-citation><mixed-citation xml:lang="en">Salvarani C. Clinical features and epidemiology of spondylarthritis associated with inflammatory bowel disease. C. Salvarani, W. Fries. World J Gastroenterol. 2009. No. 15 (20). Alvilde M Ossum, et al. P. 2449–2455.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Turkcapar N. et al. The prevalence of extraintestinal manifestations and HLA association in patients with inflammatory bowel disease. Rheumatology International. 2006. V. 26. P. 663–668.</mixed-citation><mixed-citation xml:lang="en">Turkcapar N. et al. The prevalence of extraintestinal manifestations and HLA association in patients with inflammatory bowel disease. Rheumatology International. 2006. V. 26. P. 663–668.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Rudwaleit M. Referral strategies for early diagnosis of axial spondyloarthritis. M. Rudwaleit, J. Sieper. Nature Reviews Rheumatology. 2012. No. 8 (5). P. 262–268.</mixed-citation><mixed-citation xml:lang="en">Rudwaleit M. Referral strategies for early diagnosis of axial spondyloarthritis. M. Rudwaleit, J. Sieper. Nature Reviews Rheumatology. 2012. No. 8 (5). P. 262–268.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Sieper J. et al. New criteria for inflammatory back pain in patients with chronic back pain: A real patient exercise by experts from the Assessment of SpondyloArthritis international Society (ASAS). Annals of the Rheumatic Diseases. 2009. V. 68. No. 6. P. 784–788.</mixed-citation><mixed-citation xml:lang="en">Sieper J. et al. New criteria for inflammatory back pain in patients with chronic back pain: A real patient exercise by experts from the Assessment of SpondyloArthritis international Society (ASAS). Annals of the Rheumatic Diseases. 2009. V. 68. No. 6. P. 784–788.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Alvilde M. Ossum, et al. Ankylosing Spondylitis and Axial Spondyloarthritis in Patients with Long-term Inflammatory Bowel Disease: Results From 20 Years of Follow-up in the IBSEN Study. Alvilde M Ossum [et al.]. Journal of Crohn's and Colitis. 2018. Vol. 12. No. 1. P. 96–104.</mixed-citation><mixed-citation xml:lang="en">Alvilde M. Ossum, et al. Ankylosing Spondylitis and Axial Spondyloarthritis in Patients with Long-term Inflammatory Bowel Disease: Results From 20 Years of Follow-up in the IBSEN Study. Alvilde M Ossum [et al.]. Journal of Crohn's and Colitis. 2018. Vol. 12. No. 1. P. 96–104.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Elding S. W. Refinement in localization and identification of gene regions associated with Crohn disease. S.W. Elding [et al.]. American Journal of Human Genetics. 2013. Vol. 92. No. 1. Р. 107–113.</mixed-citation><mixed-citation xml:lang="en">Elding S. W. Refinement in localization and identification of gene regions associated with Crohn disease. S.W. Elding [et al.]. American Journal of Human Genetics. 2013. Vol. 92. No. 1. Р. 107–113.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Thjodleifsson B. A common genetic background for inflammatory bowel disease and ankylosing spondylitis: A genealogic study in Iceland. B. Thjodleifsson [et al.]. Arthritis and Rheumatism. 2007. Vol. 56. No. 8. Р. 2633–2639.</mixed-citation><mixed-citation xml:lang="en">Thjodleifsson B. A common genetic background for inflammatory bowel disease and ankylosing spondylitis: A genealogic study in Iceland. B. Thjodleifsson [et al.]. Arthritis and Rheumatism. 2007. Vol. 56. No. 8. Р. 2633–2639.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Asquith M. The interaction between host genetics and the microbiome in the pathogenesis of spondyloarthropathies. M. Asquith, J. T. Rosenbaum. Current Opinion in Rheumatology. 2016. Vol. 28. No. 4. Р. 405–412.</mixed-citation><mixed-citation xml:lang="en">Asquith M. The interaction between host genetics and the microbiome in the pathogenesis of spondyloarthropathies. M. Asquith, J. T. Rosenbaum. Current Opinion in Rheumatology. 2016. Vol. 28. No. 4. Р. 405–412.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Van Praet L. Microscopic gut inflammation in axial spondyloarthritis: A multiparametric predictive model. L. Van Praet [et al.]. Annals of the Rheumatic Diseases. 2013. Vol. 72. No. 3. Р. 414–417.</mixed-citation><mixed-citation xml:lang="en">Van Praet L. Microscopic gut inflammation in axial spondyloarthritis: A multiparametric predictive model. L. Van Praet [et al.]. Annals of the Rheumatic Diseases. 2013. Vol. 72. No. 3. Р. 414–417.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Matzkies F. G. Markers of intestinal inflammation in patients with ankylosing spondylitis: A pilot study. F. G. Matzkies [et al.] Arthritis Research and Therapy. 2012. Vol. 14. No. 6. Р. R261.</mixed-citation><mixed-citation xml:lang="en">Matzkies F. G. Markers of intestinal inflammation in patients with ankylosing spondylitis: A pilot study. F. G. Matzkies [et al.] Arthritis Research and Therapy. 2012. Vol. 14. No. 6. Р. R261.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Абдулганиева Д. И. и др. Проект междисциплинарных рекомендаций по диагностике, методам оценки степени активности воспалительного процесса, терапевтической эффективности и применению генно-инженерных биологических препаратов у пациентов с сочетанными иммуновоспалительными заболеваниями (псориаз, псориатический артрит, болезнь Крона). Альманах клинической медицины. 2018. Т. 46. № 5. С. 426–444. DOI: 10.18786/2072–0505–2018–46–5–426–444.</mixed-citation><mixed-citation xml:lang="en">Abdulganieva D.I., at al. A draft of the interdisciplinary guidelines for diagnosis, methods for assessment of the degree of inflammatory activity, therapeutic efficacy, and for the use of biological agents in patients with concomitant immunoinflammatory diseases (psoriasis, psoriatic arthritis, Crohn's disease). Almanac of Clinical Medicine. 2018. Vol. 46. No. 5. P. 426–444. DOI: 10.18786/2072–0505–2018–46–5–426–444.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
