medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2023-29-8-14medalphabet-3406Research ArticleСтатьиФетальное программирование как тренд современной медицины: в фокусе дефицит магнияFetal programming as a trend in modern medicine: Magnesium deficiency is the focushttps://orcid.org/0000-0003-3220-0333НикитинаЕ. А.NikitinaЕ. А.

Никитина Елена Александровна, к.м.н., доцент кафедры диетологии и клинической нутрициологии; научный сотрудник

Москва

Nikitina Elena A., PhD Med, assistant professor of Dept of Dietetics and Clinical Nutritiology; Researcher

Moscow

nikitina-ea1@rudn.ruhttps://orcid.org/0000-0002-4689-3591ОрловаС. В.OrlovaS. V.

Орлова Светлана Владимировна, д.м.н., проф., зав. кафедрой диетологии и клинической нутрициологии; главный научный сотрудник

Москва

Orlova Svetlana V., DM Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology; Chief Researcher

Moscow

orlova-sv@rudn.ruhttps://orcid.org/0000-0003-0928-2131БатышеваТ. Т.BatyshevaТ. Т.

Батышева Татьяна Тимофеевна, д.м.н., проф., директор; глав. внештатный детский специалист-невролог ДЗМ, гл. внештатный детский специалист по медицинской реабилитации Минздрава России, зав. кафедрой неврологии, физической, реабилитационной медицины и психологии детского возраста; заслуженный врач РФ

Москва

Batysheva Tatyana T., DM Sci (habil.), professor, director; head. freelance pediatric specialist neurologist of the Department of Healthcare, head. freelance children’s specialist in medical rehabilitation of the Ministry of Health of the Russian Federation, head. Department of Neurology, Physical, Rehabilitation Medicine and Childhood Psychology, Federal Scientific Educational Institution MI RUDN University, Honored Doctor of the Russian Federation

Moscow

batysheva-tt@rudn.ruhttps://orcid.org/0000-0002-0548-3414БалашоваН. В.BalashovaN. V.

Балашова Наталья Валерьевна, к.б.н., доцент кафедры клинической лабораторной диагностики факультета усовершенствования врачей; доцент кафедры диетологии и клинической нутрициологии

Author ID: 832745

Москва

Balashova Natalya V., PhD Bio Sci, assistant professor at Dept of Clinical Laboratory Diagnostics of the Faculty of Advanced Training of Doctors; assistant professor at Dept of Dietetics and Clinical Nutritiology

Author ID: 832745

Moscow

 

BalashovaN77@mail.ruhttps://orcid.org/0000-0001-8448-8493АлексееваМ. В.AlekseevaМ. V.

Алексеева Марина Валерьевна, к.м.н., зам. директора по организационно-методической работе

Москва

Alekseeva Marina V., PhD Med, deputy director for Organizational andMethodological Work

 

marina.lal@mail.ruhttps://orcid.org/0000-0003-4214-606XВолковаЛ. Ю.VolkovaL. Yu.

Волкова Людмила Юрьевна, ст. преподаватель; к.м.н

Москва

Volkova Lyudmila Yu., PhD Med, senior teacher

Moscow

volkova2912@gmail.comhttps://orcid.org/0000-0002-5203-1082ВодолазкаяА. Н.VodolazkayaA. N.

Водолазкая Ангелина Николаевна, врач-эндокринолог, диетолог, руководитель направления обучения по нутрициологии

Москва

Vodolazkaya Angelina N., endocrinologist, dietitian, head of nutrition training

Moscow

drvodolazkaya@gmail.comhttps://orcid.org/0000-0002-3811-9459ПрокопенкоЕ. В.ProkopenkoE. V.

Прокопенко Елена Валерьевна, врач-эндокринолог, диетолог, ведущий менеджер проектов медицинского департамента

Москва

Prokopenko Elena V., endocrinologist, dietitian, senior project manager of Medical Department

Moscow

elvprokopenko@gmail.comФГАОУ ВО «Российский университет дружбы народов» имени Патриса Лумумбы; ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»РоссияPeoples’ Friendship University of Russia named after Patrice Lumumba; Scientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of HealthRussian FederationФГАОУ ВО «Российский университет дружбы народов» имени Патриса Лумумбы; ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М.Ф. Владимирского»РоссияPeoples’ Friendship University of Russia named after Patrice Lumumba; Moscow Regional Research Clinical Institute named after M. F. VladimirskyRussian FederationГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»РоссияScientific and Practical Center for Pediatric Psychoneurology of the Moscow Department of HealthRussian FederationФГБУ «НМИЦ терапии и профилактической медицины» Минздрава РоссииРоссияNational Medical Research Center for Therapy and Preventive MedicineRussian FederationАвстрийская клиника микронутриентной терапии BiogenaРоссияAustrian clinic of micronutrient therapy BiogenaRussian FederationООО «ИНВИТРО»РоссияINVITRO Limited Liability CompanyRussian Federation202304122023029«Диетология и нутрициология» (2)814Copyright © Никитина Е.А., Орлова С.В., Батышева Т.Т., Балашова Н.В., Алексеева М.В., Волкова Л.Ю., Водолазкая А.Н., Прокопенко Е.В., 20232023Никитина Е.А., Орлова С.В., Батышева Т.Т., Балашова Н.В., Алексеева М.В., Волкова Л.Ю., Водолазкая А.Н., Прокопенко Е.В.Nikitina Е.А., Orlova S.V., Batysheva Т.Т., Balashova N.V., Alekseeva М.V., Volkova L.Y., Vodolazkaya A.N., Prokopenko E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/3406

В последние годы были проведены многочисленные исследования по выявлению роли микроэлементов в патологии и клинической практике. Особое внимание уделяется роли запасов магния у матери во время беременности как ключевого фактора внутриутробного развития плода и в постнатальной жизни, а также последствиям дефицита магния у матери во время беременности на состояние здоровья ребенка при рождении, в детстве и взрослом возрасте. К настоящему времени исследования показали связь между недостаточностью магния и некоторыми состояниями во время беременности, связанными с высокой смертностью и заболеваемостью, такими как гестационный диабет, преждевременные роды, преэклампсия, а также рождение младенцев малых для гестационного возраста или с задержкой внутриутробного развития. Низкие запасы магния у матери во время беременности следует включать в число многочисленных факторов, лежащих в основе фетального программирования заболеваний у взрослых.

In recent years, numerous studies have been carried out to identify the role of trace elements in pathology and clinical practice. Particular attention is paid to the role of maternal magnesium reserves during pregnancy, as a key factor in intrauterine development of the fetus and in postnatal life, as well as the consequences of maternal magnesium deficiency during pregnancy on health status at birth, in childhood and adulthood. To date, research has shown an association between magnesium deficiency and several conditions during pregnancy associated with high mortality and morbidity, such as gestational diabetes, preterm birth, preeclampsia, and small for gestational age infants or intrauterine growth restriction. Low maternal magnesium stores during pregnancy should be included among the many factors underlying fetal programming of disease in adults.

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The authors declare that there are no conflicts of interest present.