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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-25-14-20</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3360</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Антикоагулянтная терапия у пациентов с фибрилляцией предсердий и хронической болезнью почек: за или против</article-title><trans-title-group xml:lang="en"><trans-title>Anticoagulant therapy in patients with atrial fibrillation and chronic kidney disease: Arguments for or against</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8633-7012</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комарова</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Komarova</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Комарова Анна Григорьевна, к.м.н., врач-кардиолог, зам. гл. врача по региональному сосудистому центру</p></bio><bio xml:lang="en"><p>Komarova Anna G., PhD Med, cardiologist, deputy chief physician for Regional Vascular Centre</p></bio><email xlink:type="simple">bellis-06@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ляхова</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyakhova</surname><given-names>N. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ляхова Наталия Леонидовна, к.м.н., врач-кардиолог, зав. кардиологическим отделением № 4</p></bio><bio xml:lang="en"><p>Lyakhova Natalia L., PhD Med, cardiologist, head of Cardiology Dept No. 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7236-5699</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кованцев</surname><given-names>С. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Covantsev</surname><given-names>S. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кованцев Сергей Дмитриевич, врач-хирург, н.с. </p></bio><bio xml:lang="en"><p>Covantsev Serghei D., general surgeon, researcher</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-1994-871X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нарышкина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Naryshkina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нарышкина Екатерина Александровна, врач-кардиолог</p></bio><bio xml:lang="en"><p>Naryshkina Ekaterina A., cardiologist</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8121-6713</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слепухова</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Slepukhova</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Слепухова Диана Витальевна, врач-хирург, аспирант кафедры хирургии</p></bio><bio xml:lang="en"><p>Slepukhova Diana V., MD, general surgeon, PhD student at Dept of Surgery</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ г. Москвы «Городская клиническая больница имени С.П. Боткина Департамента здравоохранения Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Botkin Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy for Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>08</day><month>11</month><year>2023</year></pub-date><volume>0</volume><issue>25</issue><issue-title>Кардиология. Неотложная медицина (3)</issue-title><fpage>14</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Комарова А.Г., Ляхова Н.Л., Кованцев С.Д., Нарышкина Е.А., Слепухова Д.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Комарова А.Г., Ляхова Н.Л., Кованцев С.Д., Нарышкина Е.А., Слепухова Д.В.</copyright-holder><copyright-holder xml:lang="en">Komarova A.G., Lyakhova N.L., Covantsev S.D., Naryshkina E.A., Slepukhova D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3360">https://www.med-alphabet.com/jour/article/view/3360</self-uri><abstract><p>Фибрилляция предсердий, как и хроническая почечная недостаточность, являются распространенными состояниями среди населения, имеющие схожи факторы риска. Оба заболевания являются независимыми факторами риска развития тромбоэмболических осложнений. Существуют неопровержимые доказательства, подтверждающие преимущества антикоагулянтной терапии при фибрилляции предсердий в общей популяции, однако у пациентов с прогрессирующей хронической почечной недостаточностью возможность применения антикоагулянтов может быть ограничена. Ряд исследований показали противоречивые результаты, и данная тема представляет интерес для дальнейшего обсуждения и всестороннего анализа существующей проблемы.</p></abstract><trans-abstract xml:lang="en"><p>Atrial fibrillation and chronic renal failure are common diseases in the population with similar risk factors. Both conditions are independent riskfactors for the development of thromboembolic complications. There is compelling evidence to support the benefits of anticoagulant therapy for atrial fibrillation in the general population, but in patients with advanced chronic renal failure, the use of anticoagulants may be limited. A number of studies have shown conflicting results, and this topic is of interest for further discussion and a comprehensive analysis of the existing data.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая болезнь почек</kwd><kwd>фибрилляция предсердий</kwd><kwd>тромбоэмболия</kwd><kwd>инсульт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic kidney disease</kwd><kwd>atrial fibrillation</kwd><kwd>thromboembolism</kwd><kwd>stroke.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Go A.S., Hylek E.M., Phillips K.A., Chang Y., Henault L.E., Selby J.V., et al. 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