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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-22-50-55</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3356</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Систолическая функция левого и правого желудочков и показатели деформации миокарда у лиц молодого возраста с метаболическим синдромом</article-title><trans-title-group xml:lang="en"><trans-title>Systolic function of the left and right ventricles and myocardial strain in young adults with metabolic syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7300-1942</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бартош-Зеленая</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Bartosh-Zelenaya</surname><given-names>S. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры функциональной диагностики</p></bio><bio xml:lang="en"><p>DMedSci, Professor</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-7141-0586</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач отделения функциональной диагностики. Аспирантка 3-го года кафедры функциональной диагностики</p></bio><bio xml:lang="en"><p>specialist of functional diagnostics department of City Hospital</p></bio><email xlink:type="simple">vikkistepanova16@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4443-5797</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлова</surname><given-names>Н. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlova</surname><given-names>N. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач отделения функциональной диагностики</p></bio><bio xml:lang="en"><p>specialist of functional diagnostics department of City Hospital</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4722-6950</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамаева</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamaeva</surname><given-names>O. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p> заведующая отделением функциональной диагностики</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, chief of functional diagnostics department of City Hospital</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5047-2792</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербак</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sherbak</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедройпоследипломного образования Медицинского факультета Санкт-Петербургского государственного университета, главный врач СПб ГБУЗ Городская больница №40 МЗ РФ</p></bio><bio xml:lang="en"><p>MD, PhD, DMedSci, Professor, head of Postgraduate Medical education at St.Petersburg State University, chief physician of City Hospital</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-Западный государственный медицинский университет им. И. И. Мечникова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University by I. I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>СПб ГБУЗ, «Городская больница № 40 Курортного района»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State hospital № 40</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>08</day><month>11</month><year>2023</year></pub-date><volume>1</volume><issue>22</issue><issue-title>Современная функциональная диагностика (3)</issue-title><fpage>50</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бартош-Зеленая С.Ю., Степанова В.В., Павлова Н.Е., Мамаева О.П., Щербак С.Г., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Бартош-Зеленая С.Ю., Степанова В.В., Павлова Н.Е., Мамаева О.П., Щербак С.Г.</copyright-holder><copyright-holder xml:lang="en">Bartosh-Zelenaya S.Y., Stepanova V.V., Pavlova N.E., Mamaeva O.P., Sherbak S.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3356">https://www.med-alphabet.com/jour/article/view/3356</self-uri><abstract><p>Целью этой статьи является оценка систолической функции левого и правого желудочков и показателей деформации миокарда у лиц молодого возраста (от 18 до 44 лет) с впервые установленным клинико-лабораторным диагнозом метаболический синдром (МС) согласно критериям Международной федерации диабетологов (IDF), для выявления ранних маркеров дисфункции миокарда. Всем участникам проводилась стандартная трансторакальная эхокардиография (ЭхоКГ) с оценкой систолической функции левого и правого желудочков (ЛЖ и ПЖ). В работе определяли ранние маркеры дисфункции миокарда желудочков с помощью технологии Speckle tracking в 2D- и 4D-режиме, а также исследовали взаимосвязи между основными компонентами МС и эхокардиографическими показателями. С помощью сравнительного анализа были выявлены статистически значимо низкие значения глобальной продольной деформации ЛЖ и ПЖ в 2D- и 4D- режимах в основной группе по сравнению с группой контроля. У лиц с МС, средние значения циркулярной (GCS), радиальной (GRS) деформации и площади деформации (GAS) ЛЖ также были значительно ниже контрольной группы. Показатели ожирения (масса тела и окружность талии) имели отрицательную корреляцию с фракцией выброса (ФВ) и параметрами деформации желудочков сердца.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of this article is to evaluate the systolic function of the left and right ventricles and measure myocardial Strain in young people (from 18 to 44 years old) with a newly established clinical and laboratory diagnosis of metabolic syndrome (MS) according to the criteria of the International Diabetes Federation (IDF), to identify possible early markers of myocardial dysfunction. All patients underwent standard transthoracic echocardiography (EchoCG) with assessment of systolic function of the left and right ventricles (LV and RV). The work detects early markers of ventricular myocardial dysfunction using speckle tracking 2D and 4D EchoCG, and also investigates the relationship between the main components of MS and echocardiographic parameters. With the help of a comparative analysis, statistical data were revealed on the low global longitudinal strain of the left and right ventricle in 2D and 4D in the main group compared with the control group. In individuals with MS, the mean values of global circular strain (GCS), radial (GRS) strain and global area strain (GAS) of the left ventricle were also significantly lower than the control group. Indicators obesity diseases (body weight and waist circumference) had a negative correlation with the ejection fraction (EF) and parameters of ventricular strain.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метаболический синдром</kwd><kwd>эхокардиография</kwd><kwd>спекл- трекинг-эхокардиография</kwd><kwd>фракция выброса</kwd><kwd>деформация миокарда</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metabolic syndrome</kwd><kwd>echocardiography speckle tracking echocardiography</kwd><kwd>injection fraction</kwd><kwd>myocardial strain</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алехин М. Н. Двухмерная спекл-трекинг-эхокардиография для оценки деформации миокарда и камер сердца: Учебное пособие / Алехин М. Н. — М.: Издательский дом Видар-М, 2022. — 112 с.</mixed-citation><mixed-citation xml:lang="en">Алехин М. Н. 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