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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-328</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Высокопоточная оксигенотерапия при лечении острой дыхательной недостаточности различного генеза: возможности и перспективы</article-title><trans-title-group xml:lang="en"><trans-title>High-flow oxygen therapy in treatment of acute respiratory failure of various genesis: opportunities and prospects</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Власенко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vlasenko</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корякин</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Koryakin</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евдокимов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Evdokimov</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ДПО «Российская медицинская академия непрерывного последипломного образования» Минздрава России; ГБУЗ г. Москвы «Городская клиническая больница имени С. П. Боткина» Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy for Postgraduate Continuous Education; City Clinical Hospital n.a. S. P. Botkin</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>19</day><month>09</month><year>2017</year></pub-date><volume>3</volume><issue>29</issue><issue-title>Неотложная медицина</issue-title><fpage>16</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Власенко А.В., Корякин А.Г., Евдокимов Е.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Власенко А.В., Корякин А.Г., Евдокимов Е.А.</copyright-holder><copyright-holder xml:lang="en">Vlasenko A.V., Koryakin A.G., Evdokimov E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/328">https://www.med-alphabet.com/jour/article/view/328</self-uri><abstract><p>Профилактика, диагностика и лечение тяжелой дыхательной недостаточности были и остаются одними из наиболее актуальных проблем медицины и реаниматологии. Несмотря на бурный прогресс методов жизнеобеспечения и респираторных технологий, искусственная вентиляция легких не в состоянии адекватно и безопасно протезировать функцию внешнего дыхания. Поэтому сохранение спонтанного дыхания больного и применение вспомогательных неинвазивных способов респираторной поддержки при отсутствии противопоказаний представляется перспективным направлением лечения острой дыхательной недостаточности, особенно на ранних стадиях. В последние годы в клиническую практику активно внедряется инновационная респираторная технология, позволяющая неинвазивно доставлять больному воздушно-кислородную смесь с большой скоростью потока (до 60 л в минуту). Высокопоточная оксигенотерапия (high flow oxygen therapy, HFOT) обеспечивает не только высокую скорость потока, но и эффективное увлажнение и согревание воздушно-газовой смеси с точным контролем фракции кислорода. Различные исследования показали, что высокопоточная оксигенотерапия представляется эффективным и хорошо переносимым методом неинвазивной респираторной поддержки при дыхательной недостаточности различного генеза. Целью настоящей публикации является обзор литературных данных и предварительных результатов собственных исследований применения высокопоточной оксигенотерапии в разных клинических ситуациях.</p></abstract><trans-abstract xml:lang="en"><p>Prevention, diagnosis and treatment of severe acute respiratory failure have been and remain one of the urgent problems of medicine and resuscitation. Despite the rapid progress of life support methods and respiratory technologies, artificial lung ventilation is not able to adequately and safely replacement of respiratory function. Therefore, the preservation of the patient spontaneous breathing and the use of non-invasive respiratory support methods, in the absence of contraindications, seems to be a promising direction for the treatment of acute respiratory failure, especially in the early stages. In recent years, innovative respiratory technology is actively being introduced into clinical practice, which allows to deliver the air-oxygen mixture with a high flow rate (up to 60 liters per minute) in an no invasive manner. High flow oxygen therapy (HFOty provides not only a high flow rate, but also an effective humidity and warming of the air-gas mixture with precise control of the oxygen fraction. Various studies have shown that high-flow oxygen therapy (HPV) seems to be an effective and well tolerated method for non-invasive respiratory support in respiratory failure of various genesis. The aim of this publication is to review the literature data and preliminary results of our own studies on the use of HFOT in different clinical situations.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дыхательная недостаточность</kwd><kwd>респираторная поддержка</kwd><kwd>неинвазивная вентиляция легких</kwd><kwd>высокопоточная оксигенотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>respiratory failure</kwd><kwd>respiratory support</kwd><kwd>non-invasive ventilation</kwd><kwd>high-flow oxygen therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Власенко А. В., Мороз В. В., Яковлев В. Н., Алексеев В. Г. Дифференцированное лечение острого респираторного дистресс-синдрома. Новости анестезиологии и реаниматологии. 2012, № 4: С. 23-33.</mixed-citation><mixed-citation xml:lang="en">Власенко А. В., Мороз В. В., Яковлев В. Н., Алексеев В. Г. 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