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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-16-34-40</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3256</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Изучение показателей артериальной ригидности у лиц молодого возраста в зависимости от «классических» и «современных» факторов риска</article-title><trans-title-group xml:lang="en"><trans-title>Study of indicators of arterial stiffness in young people depending on ‘classical’ and ‘modern’ risk factors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7505-2698</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пушкина</surname><given-names>Я. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pushkina</surname><given-names>Ya. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пушкина Яна Александровна, очный аспирант кафедры</p><p>г. Саранск</p></bio><bio xml:lang="en"><p>Pushkina Yana A., full-time postgraduate student of Dept. of Faculty Therapy with courses of physiotherapy, physical therapy of Medical Institute</p><p>Saransk</p></bio><email xlink:type="simple">frolkina1992yana@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4324-9071</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гончарова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Goncharova</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гончарова Людмила Никитична, д. м. н., доцент, проф. кафедры</p><p>г. Саранск</p></bio><bio xml:lang="en"><p>Goncharova Ludmila N., DM Sci (habil.), associate professor, professor at Dept. of Faculty Therapy with courses of physiotherapy, physical therapy of Medical Institute</p><p>Saransk</p></bio><email xlink:type="simple">glnsm@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8274-7906</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергутова</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergutova</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергутова Наталья Петровна, к. м.н, доцент кафедры</p><p>г. Саранск</p></bio><bio xml:lang="en"><p>Sergutova Natalia P., PhD Med, associate professor at Dept. of Faculty Therapy with courses of physiotherapy, physical therapy of Medical Institute</p><p>Saransk</p></bio><email xlink:type="simple">sergutovanp@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1559-4721</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антипова</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Antipova</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Антипова Валентина Николаевна, к. м. н., доцент, проф. кафедры</p><p>г. Саранск</p></bio><bio xml:lang="en"><p>Antipova Valentina N., PhD Med, associate professor, professor at Dept. of Faculty Therapy with courses of physiotherapy, physical therapy of Medical Institute</p><p>Saransk</p></bio><email xlink:type="simple">valentina.antipova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8440-6598</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левашова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Levashova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Левашова Ольга Анатольевна, к. б. н., доцент кафедры медицинской микробиологии и лабораторной медицины</p><p>г. Пенза</p></bio><bio xml:lang="en"><p>Levashova Olga A., PhD Bio, associate professor at Dept of Medical Microbiology and Laboratory Medicine</p><p>Penza</p></bio><email xlink:type="simple">olga.lewashowa@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7206-1767</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белькин</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Belkin</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белькин Юрий Алексеевич, к. м. н., доцент кафедры терапии и кардиологии медицинского института</p><p>Нижний Новгород</p></bio><bio xml:lang="en"><p>Belkin Yury A., PhD Med, associate professor at Dept. of Faculty Therapy and Cardiology of Medical Institute</p><p>Nizhny Novgorod</p></bio><email xlink:type="simple">postdiplom@pimunn.mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра факультетской терапии с курсами физиотерапии, лечебной физкультуры медицинского института ФГБОУ ВО «Национальный исследовательский Мордовский государственный университет имени Н. П. Огарева»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research Mordovian State University n. a. N. P. Ogaryov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Пензенский институт усовершенствования врачей – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza Institute for Postgraduate Medicine – a Branch of Russian Medical Academy for Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Privolzhsky Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2023</year></pub-date><volume>0</volume><issue>16</issue><issue-title>Кардиология. Неотложная медицина (2)</issue-title><fpage>34</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пушкина Я.А., Гончарова Л.Н., Сергутова Н.П., Антипова В.Н., Левашова О.А., Белькин Ю.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Пушкина Я.А., Гончарова Л.Н., Сергутова Н.П., Антипова В.Н., Левашова О.А., Белькин Ю.А.</copyright-holder><copyright-holder xml:lang="en">Pushkina Y.A., Goncharova L.N., Sergutova N.P., Antipova V.N., Levashova O.A., Belkin Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3256">https://www.med-alphabet.com/jour/article/view/3256</self-uri><abstract><p>Цель. Выявить «классические» и «современные» факторы риска (ФР) у лиц молодого возраста 18–25 лет в студенческой среде и оценить их влияние на показатели ригидности артериальной стенки с помощью неинвазивных методов обследования.Материалы и методы. Обследован 171 студент гуманитарного вуза 18–25 лет, из них 52,1 % – девушки и 47,9 % – юноши. Для выявления основных ФР проведен анонимный опрос. Методом объемной сфигмографии и высокочувствительной компрессионной осциллометрии проведена оценка состояния сосудистой стенки.Результаты. На фоне «классических» ФР (низкая физическая активность – 61,9 %, эссенциальная артериальная гипертензия [АГ] – 29,8 %, отягощенная наследственность по АГ – 18,3 %, избыточная масса тела – 14,0 %, ожирение – 8,5 %, курение сигарет – 3,0 %), выявлены «современные» ФР: сочетание курения кальяна и сигарет – 31,0 %, использование электронных сигарет – 17,0 %, употребление энергетических напитков – 25,3 %. У студентов с наличием «современных» ФР получены значения скорости пульсовой волны (PWV) – 8,4 ± 2,7 м/с, относительно PWV у студентов без ФР – 5,1 ± 0,6 м/с (p = 0,002). Установлено, что относительный риск увеличения PWV при комбинированном использовании кальяна и сигарет возрастает в 52,1 раза (95 % ДИ: 11,2–242,1 при χ2 = 37,987; р = 0,001), при употреблении энергетических напитков – в 27,4 раза (95 % ДИ: 6,8–111,0 при χ2 = 29,328; р = 0,001), при использовании электронных сигарет – в 2,6 раза (95 % ДИ: 1,3–5,2 при χ2 = 6,496; р = 0,011).Выводы. У студентов 18–25 лет выявлена высокая приверженность к современным ФР (сочетание курения кальяна и сигарет, прием энергетических напитков, использование электронных сигарет), которые приводят к нарушению упруго-эластических свойств сосудистой стенки, что указывает на эндотелиальную дисфункцию.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To identify ‘classical’ and ‘modern’ risk factors (RFs) in young people aged 18–25 years in a student environment and evaluate their impact on arterial wall stiffness using non-invasive examination methods.Materials and methods. 171 students of a humanitarian university aged 18–25 years old were examined, of which 52.1 % were girls and 47.9 % were boys. An anonymous survey was conducted to identify the main risk factors. The method of volumetric sphygmography and highly sensitive compression oscillometry was used to assess the state of the vascular wall.Results. Against the background of ‘classic’ risk factors (low physical activity – 61.9 %, essential arterial hypertension [AH] – 29.8 %, aggravated heredity for hypertension – 18.3 %, overweight – 14.0 %, obesity – 8.5 %, cigarette smoking – 3.0 %), ‘modern’ RFs were identified: a combination of hookah and cigarette smoking – 31.0 %, use of electronic cigarettes – 17.0 %, use of energy drinks – 25.3 %. In students with the presence of ‘modern’ PR, the values of pulse wave velocity (PWV) were obtained – 8.4 ± 2.7 m/s, relative to the PWV of students without PR 5.1 ± 0.6 m/s (p = 0.002). It was found that the relative risk of an increase in PWV with the combined use of hookah and cigarettes increases by 52.1 times (95 % CI: 11.2–242.1 at χ2 = 37.987; p = 0.001), with the use of energy drinks by 27.4 times (95 % CI: 6.8–111.0 at χ2 = 29.328; p = 0.001), when using electronic cigarettes by 2.6 times (95 % CI: 1.3–5.2 at χ2 = 6.496; p = 0.011).Conclusions. Students aged 18–25 years showed a high adherence to modern risk factors (a combination of hookah and cigarette smoking, energy drinks, use of electronic cigarettes) that lead to a violation of the elastic properties of the vascular wall, which indicates endothelial dysfunction.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>молодой возраст</kwd><kwd>современные факторы риска</kwd><kwd>артериальная ригидность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>young age</kwd><kwd>current risk factors</kwd><kwd>arterial stiffness</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Щербакова Е. М. Демографические итоги I полугодия 2019 года в России (часть II). Демоскоп Weekly. 2019. № 825–8246.</mixed-citation><mixed-citation xml:lang="en">Shcherbakova EM Demographic results of the first half of 2019 in Russia (part II). Demoscope Weekly. 2019. No. 825–8246. (In Russ.) 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