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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-12-72-74</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3230</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Применение метода полимеразной цепной реакции  (ПЦР) в реальном времени для определения  пародонтопатогенов</article-title><trans-title-group xml:lang="en"><trans-title>Application of the real-time PCR-method for the determination  of periodontopathogens</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9995-3749</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джафаров</surname><given-names>Э. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Jafarov</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Джафаров Эльнур Матлаб оглы - заочный аспирант кафедры стоматологии общей практики и детской стоматологии </p></bio><bio xml:lang="en"><p>Jafarov Elnur Matlab oglu - postgraduate student of the Department of general practice dentistry and pediatric dentistry</p></bio><email xlink:type="simple">elnur985@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1711-1415</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эдишерашвили</surname><given-names>У. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Edisherashvili</surname><given-names>U. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Эдишерашвили Ушанги Бесикович -  заочный аспирант кафедры стоматологии общей практики и детской стоматологии </p></bio><bio xml:lang="en"><p>Edisherashvili Ushangi Besikovich - postgraduate student of the Department of General Practice Dentistry and Pediatric Dentistry</p></bio><email xlink:type="simple">ushangi.master@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чониашвили</surname><given-names>М. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Choniashvili</surname><given-names>M. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чониашвили Марина Зурабовна - старший ассистент кафедры терапевтической, хирургической и детской стоматологии с курсом геронтология и заболевания полости рта</p></bio><bio xml:lang="en"><p>Marina Zurabovna Choniashvili - Senior Assistant of Therapeutic, Surgical and Pediatric Dentistry with a Course of Gerontology and Oral Diseases</p></bio><email xlink:type="simple">Choniashvil.marina@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таймазова</surname><given-names>Д. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Taimazova</surname><given-names>D. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Таймазова Диляра Тимуровна -  врач стоматолог-терапевт</p><p>г. Владикавказ</p></bio><bio xml:lang="en"><p>Dilyara Timurovna Taimazova - Dentist-therapist</p><p>Vladikavkaz</p></bio><email xlink:type="simple">dilya.04@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6352-6750</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долгалев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolgalev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Долгалев Александр Александрович - д.м.н., доцент, профессор кафедры стоматологии общей практики и детской стоматологии, заведующий лабораторий трансфера инновационных медицинских изделий и технологий</p></bio><bio xml:lang="en"><p>Dolgalev Alexander Alexandrovich - PhD, MD, Head of the Center for Innovation and Technology Transfer, Professor of the Department of General Practice Dentistry and Pediatric Dentistry</p></bio><email xlink:type="simple">dolgalev@dolgalev.pro</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВПО «Ставропольский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Professional Education «Stavropol State Medical University», Ministry of HealthCare</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Северо-Осетинский государственный университет имени Коста Левановича Хетагурова» Министерства науки и высшего образования Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Professional Education «Kosta Khetagurov North Ossetian State University Ministry of Science and Higher Education»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>«Городская стоматологическая поликлиника № 1»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>«City Dental Clinic № 1»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>17</day><month>10</month><year>2023</year></pub-date><volume>0</volume><issue>12</issue><issue-title>Стоматология (2)</issue-title><fpage>72</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Джафаров Э.М., Эдишерашвили У.Б., Чониашвили М.З., Таймазова Д.Т., Долгалев А.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Джафаров Э.М., Эдишерашвили У.Б., Чониашвили М.З., Таймазова Д.Т., Долгалев А.А.</copyright-holder><copyright-holder xml:lang="en">Jafarov E.M., Edisherashvili U.B., Choniashvili M.Z., Taimazova D.T., Dolgalev A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3230">https://www.med-alphabet.com/jour/article/view/3230</self-uri><abstract><p>Этиологическим фактором заболеваний пародонта является наличие пародонтопатогенов, при условии дисбаланса с комменсалами они начинают оказывать патологическое действие. При снижении количества пародонтопатогенов, находящихся в биопленке, возможно восстановление баланса и профилактика заболеваний пародонта или их переход в стадию ремиссии. На сегодняшний день наиболее информативным и доступном диагностическим способом определения пародонтопатогенов является полимеразная цепная реакция (ПЦР) в реальном времени.</p></abstract><trans-abstract xml:lang="en"><p>The etiological factor of periodontal diseases is the presence of periodontopathogens, under the condition of an imbalance with commensals, they begin to have a pathological effect. With a decrease in the number of periodontopathogens in the biofilm, it is possible to restore the balance and prevent periodontal diseases or their transition to the stage of remission. To date, the most informative and accessible diagnostic method for determining periodontopathogens is real-time PCR.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пародонтит</kwd><kwd>пародонтопатогены</kwd><kwd>полимеразная цепная реакция (ПЦР)</kwd><kwd>пародонт</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>periodontitis</kwd><kwd>periodontopathogens</kwd><kwd>PCR</kwd><kwd>periodontium</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Choi EJ, Lee SH, Kim YJ (2009). Quantitative real-time polymerase chain reaction for Streptococcus mutans and Streptococcus sobrinus in dental plaque samples and its association with early childhood caries. Int J Paediatr Dent 19:141–147.</mixed-citation><mixed-citation xml:lang="en">Choi EJ, Lee SH, Kim YJ (2009). 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